Genetic MYEOV/IgH (MM) DNA Test


Genetic MYEOV/IgH (MM) DNA Test

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The most common chromosomal translocation in multiple myeloma (MM) is resulting in up-regulation of cyclin D1. In MM the breakpoints are scattered within a 360-kb region between CCND1 and MYEOV.

Call: (079) 30925079
The MYEOV/IGH t(11;14) probe is designed as a dual-fusion probe to detect
both rearranged chromosomes der(11) and der(14) by two co-localized red/green or yellow fusion signals (F). Single color red (R) and green (G) signals will identify the normal chromosomes 14 and 11 respectively.
Signal patterns other than those described above may indicate variant translocations, deletions on der(11) or der(14) or other complex re
arrangements. Investigators are advised to analyze metaphase cells for the interpretation of a typical signal patterns.