HLA Typing Test at a Glance
- Sample Required: Blood or Buccal Swab
- Fasting Rules: Not required
- Turnaround Time (TAT): 5-7 days
- Base Cost: ₹8,000 per person
HLA Typing Test for Transplant: Cost, Matching, and Booking in India
Human leukocyte antigen (HLA) typing is a medical test used to assess whether organ and blood marrow donors are suitably and safely matched to a transplant recipient. HLA are proteins, or markers, found on most cells in your body. This testing is essential for bone marrow, cord blood, and solid organ transplants to minimize the risk of rejection and graft-versus-host disease.
Understanding HLA Matching
The HLA match is the number of HLA markers that any two people have in common. HLA matching is usually based on either eight or 10 HLA markers. The more markers two people share, the better the match. When two individuals share the same HLA markers, they are said to be a good match.
The most likely place to find an HLA match between two people is among siblings who have the same mother and father. If two siblings inherit the very same HLA markers from both parents, they are said to be an HLA-identical match. Two unrelated people can just happen to be a good HLA match, too. Although it is less likely, it is possible that you could have some of the same HLA markers as someone you don’t even know.
HLA Matching Levels
| Match Type | Description | Likelihood |
|---|---|---|
| HLA-Identical | Shares all 10/10 HLA markers | 25% among full siblings |
| Half Match (Haploidentical) | Shares 5/10 HLA markers (one haplotype) | Always between parent and child |
| Unrelated Match | Shares 8/10 or 10/10 markers by chance | Rare, but possible |
How Are HLA Genes Inherited?
Biological parents always share half of their HLA proteins with their children. This is also called a “half match.” Conversely, a child always is a half match with their parents. A child would share half of the colours on his cells with each of his parents. Siblings who share both parents are most likely to be an identical HLA match. Such siblings have a 1 in 4 chance of being a perfect HLA match.
Because the HLA genes are located close together on your DNA, they are usually inherited as a group—you inherit a whole set of colours, not just one individual colour at a time. Your HLA type is composed of the set of HLA genes you inherited from your mother and the HLA genes you inherited from your father. In our analogy, the HLA genes contain information about the "colour of the strings" your cells will have.
When Is HLA Typing Needed?
When a doctor decides that a bone marrow transplant is the best treatment for a patient, the patient, all of his or her siblings if they agree, and sometimes their parents will have samples collected for HLA typing. If one of the family members is an HLA-identical match, the lab will do further testing to be absolutely sure that they are the best match possible.
HLA Typing Procedure at DNA Labs India
At DNA Labs India, we use advanced molecular techniques including Next-Generation Sequencing (NGS) for high-resolution HLA typing. This ensures precise identification of HLA alleles, which is critical for transplant success. The test is performed on a blood sample or buccal swab, and results are typically available within 5-7 days.
HLA Typing Test Cost in India
The cost of the HLA Typing Test for a single person (either donor or recipient) is ₹8,000. This price is competitive and includes the high-resolution typing required for transplant matching.
How Can I Book My HLA Typing Test in India?
Visit the website www.dnalabsindia.com for any DNA test. We can help you get your DNA test done. We have services in over 180 cities in India. Call us at the below-mentioned numbers or visit our sample collection centre near your location.
- New Delhi: (011) 40849842
- Mumbai: (022) 48937160
- Kolkata: (033) 40836441
- Chennai: (044) 48137110
- Bangalore: (080) 45684079
- Hyderabad: (040) 49171772
- Ahmedabad: (079) 49107674