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DNA Labs India

18S rRNA Sequencing Test

DNA Labs India | ISO 9001:2015 Certified

18S rRNA Sequencing Test

Also known as: 18S ribosomal RNA sequencing, Eukaryotic rRNA gene sequencing

18S rRNA Sequencing Test test available at DNA Labs India for ₹5,000. Uses PCR, Sequencing on Extracted DNA samples. Results in 2 weeks. Free home collection in 300+ cities across India.

Sequencing🏠 Home Collection

🩺 Medically Reviewed By

Overview

The purpose of 18S rRNA sequencing is to accurately diagnose infections caused by eukaryotic pathogens, including parasites and fungi, by genetic identification. It helps in determining the specific organism responsible for symptoms, guiding targeted therapy, and monitoring treatment efficacy.

Test Code
3386
Price
₹5,000
Sample Type
Extracted DNA
Result Time
2 weeks
Fasting Required
No
Method
PCR, Sequencing
Step 1

Sample Collection

No specific preparation required. Inform the healthcare provider about any medications or recent infections.

Method: Blood draw, tissue biopsy, or other clinical samples

Step 2

Laboratory Analysis

Sample collection is performed by a trained phlebotomist or technician. For blood samples, a vein is punctured; for tissue, a biopsy may be taken.

Step 3

Report Delivery

Apply pressure to the collection site to prevent bleeding. Keep the area clean and dry.

Timeline: 2 weeks

Patient Instructions

1
Before the Test:No fasting required. Provide a clinical history to the healthcare provider.
2
During the Test:Sample collection takes a few minutes. The process is minimally invasive.
3
After the Test:Resume normal activities. Monitor the collection site for any adverse effects.

About This Test

Who Should Get This Test

The purpose of 18S rRNA sequencing is to accurately diagnose infections caused by eukaryotic pathogens, including parasites and fungi, by genetic identification. It helps in determining the specific organism responsible for symptoms, guiding targeted therapy, and monitoring treatment efficacy.

How to Prepare

  • Ensure proper identification of the patient
  • Use sterile collection equipment
  • Label the sample correctly with patient details
  • Transport the sample to the lab within the specified stability period

Doctor's Notes

Reviewed by — MBBS, MD (Microbiology) · Reg. No. 27670

"18S rRNA sequencing is a vital tool for diagnosing elusive infections caused by parasites and fungi, enabling targeted treatment and improved patient outcomes."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeExtracted DNA
Sample VolumeVaries based on sample
ContainerSterile tube or container
Collection MethodBlood draw, tissue biopsy, or other clinical samples

Sample Stability

Room temperature24 hours
Refrigerated (2-8°C)72 hours
Sample Rejection Criteria:
  • Sample hemolyzed or contaminated
  • Incorrect sample type
  • Insufficient volume

Understanding Your Results

Results from 18S rRNA sequencing indicate the presence or absence of specific eukaryotic pathogens. A positive result identifies the organism, while a negative result may suggest no infection or an undetectable pathogen.
📊

Positive for pathogen

Confirms infection with the identified organism. Consult a specialist for treatment.

📊

Negative

No detectable eukaryotic pathogen. Consider other diagnostic tests if symptoms persist.

📊

Inconclusive

Repeat testing or use alternative methods may be needed.

⚠️ When to Consult a Doctor:

Consult a doctor if you experience symptoms like fever, diarrhea, or skin rash, especially after travel or in immunocompromised states. Follow up on test results for appropriate management.

Limitations

  • Cannot detect all eukaryotic pathogens
  • May not differentiate between closely related species
  • Requires specialized equipment and expertise

Risks & Considerations

  • Minor bruising or pain at the collection site
  • Rare risk of infection

Interfering Factors

  • Contaminated sample
  • Insufficient DNA quantity
  • Presence of inhibitors in the sample

Frequently Asked Questions

What is 18S rRNA sequencing?
It is a molecular test that sequences the 18S ribosomal RNA gene to identify eukaryotic pathogens like parasites and fungi.
How is the test performed?
DNA is extracted from a sample, the 18S rRNA gene is amplified via PCR, and then sequenced to determine the organism's genetic makeup.
What infections can it detect?
It can detect infections caused by parasites (e.g., malaria, toxoplasmosis) and fungi (e.g., candidiasis, aspergillosis).
Is fasting required before the test?
No, fasting is not required for 18S rRNA sequencing.
What is the cost of the test?
The test costs INR 5000 at DNA Labs India, with free home sample collection.
How long does it take to get results?
Results are typically available within 2 weeks.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection across India for this test.
What are the symptoms that indicate this test?
Symptoms include fever, chills, nausea, diarrhea, abdominal pain, fatigue, weight loss, skin rash, and breathing difficulties.
How accurate is 18S rRNA sequencing?
It is highly accurate for identifying eukaryotic pathogens, with sequence accuracy often exceeding 99%.
Can this test replace traditional culture methods?
It complements culture methods by detecting pathogens that are difficult to culture, but may not replace all traditional diagnostics.
What should I do if my test is positive?
Consult an infectious disease specialist for appropriate treatment and management.
Is the test covered by insurance?
Coverage depends on your insurance policy; check with your provider for details.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.
For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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