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2x150 Hiseq Sequencing- 1 GB Test

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2x150 Hiseq Sequencing- 1 GB Test

Short Name: 2x150 HiSeq Sequencing

Also known as: HiSeq 2x150 Sequencing, NGS 1GB Sequencing, High-Throughput Sequencing

2x150 Hiseq Sequencing- 1 GB Test test available at DNA Labs India for ₹2,500. Uses Next-Generation Sequencing (NGS), Illumina HiSeq Platform on Extracted DNA samples. Results in Reports are typically delivered within 4 weeks from the date of sample receipt.. Free home collection in 300+ cities across India.

Next-Generation Sequencing🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

The purpose of the 2x150 HiSeq Sequencing (1GB) test is to provide high-resolution genetic data for the diagnosis and management of genetic conditions. It is used to identify disease-causing mutations, confirm clinical diagnoses, assess genetic predispositions, and guide targeted therapies. The paired-end sequencing approach enhances the detection of insertions, deletions, and structural variants, which are often missed by other methods. This test is valuable for patients with unexplained symptoms that may have a genetic basis, as well as for research purposes.

Test Code
6443
CPT Code
81479
ICD Code
Z01.89
Price
₹2,500
Sample Type
Extracted DNA
Result Time
Reports are typically delivered within 4 weeks from the date of sample receipt.
Fasting Required
No
Method
Next-Generation Sequencing (NGS), Illumina HiSeq Platform
Step 1

Sample Collection

No special preparation is required. However, if providing a blood sample, inform the lab about any medications or supplements you are taking.

Method: Blood or saliva sample for DNA extraction

Step 2

Laboratory Analysis

A blood sample will be drawn from a vein in your arm. For saliva, you will be asked to provide a saliva sample in a sterile container.

Step 3

Report Delivery

You can resume normal activities immediately. The sample will be processed for DNA extraction and sequencing.

Timeline: Reports are typically delivered within 4 weeks from the date of sample receipt.

Patient Instructions

1
Before the Test:No special preparation is needed. However, ensure you have a valid prescription or referral from a healthcare provider if required.
2
During the Test:The sample collection is quick and painless. For blood, a phlebotomist will draw a small amount of blood. For saliva, you will spit into a tube.
3
After the Test:You can resume normal activities immediately. The sample will be sent to the lab for processing. Results will be available in 4 weeks.

About This Test

Who Should Get This Test

The purpose of the 2x150 HiSeq Sequencing (1GB) test is to provide high-resolution genetic data for the diagnosis and management of genetic conditions. It is used to identify disease-causing mutations, confirm clinical diagnoses, assess genetic predispositions, and guide targeted therapies. The paired-end sequencing approach enhances the detection of insertions, deletions, and structural variants, which are often missed by other methods. This test is valuable for patients with unexplained symptoms that may have a genetic basis, as well as for research purposes.

How to Prepare

  • Ensure the sample is labeled correctly with your name and date of birth.
  • If providing blood, the sample should be collected in an EDTA tube.
  • For saliva, avoid eating, drinking, or smoking 30 minutes before collection.
  • Store the sample at room temperature if delivery is within 24 hours; otherwise, refrigerate.

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"This sequencing service provides high-throughput, accurate genetic data essential for diagnosing inherited disorders and guiding targeted therapies."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeExtracted DNA
Sample Volume1 µg (minimum)
ContainerEppendorf tube (DNA)
Collection MethodBlood or saliva sample for DNA extraction

Sample Stability

DNA: stable at -20°C for up to 1 year
Blood: stable at 2-8°C for up to 7 days
Saliva: stable at room temperature for up to 30 days
Sample Rejection Criteria:
  • Hemolyzed blood samples
  • Insufficient DNA quantity (< 500 ng)
  • DNA with A260/A280 ratio < 1.8
  • Sample not labeled correctly
  • Sample received after prolonged storage without proper conditions

Understanding Your Results

The results of the 2x150 HiSeq Sequencing (1GB) test are interpreted by clinical geneticists and bioinformaticians. Variants are classified according to ACMG guidelines. The report includes a list of detected variants, their clinical significance, and recommendations for further testing or clinical management.
📊

Pathogenic

Disease-causing; may explain the patient's phenotype

Action: Discuss with genetic counselor; consider targeted management

📊

Likely Pathogenic

High likelihood of disease causation; further evidence needed

Action: Additional testing or family studies may be recommended

📊

Variant of Uncertain Significance (VUS)

Insufficient evidence to determine pathogenicity

Action: Further analysis or segregation studies may be advised

📊

Likely Benign

Unlikely to cause disease

Action: No immediate action required

📊

Benign

No disease association

Action: No action required

⚠️ When to Consult a Doctor:

Consult a genetic counselor or physician if the test reveals pathogenic or likely pathogenic variants, or if you have concerns about your genetic risk. Also, consult if you have a family history of genetic disorders and are considering testing.

Limitations

  • ⚠Detects only variants in the sequenced regions; does not cover all genomic regions
  • ⚠May miss large structural variants or repeat expansions
  • ⚠Requires high-quality DNA; degraded samples may fail
  • ⚠Interpretation may be limited by incomplete reference databases
  • ⚠Not a diagnostic test for all genetic conditions; clinical correlation required

Risks & Considerations

  • ●No significant physical risks associated with blood or saliva collection
  • ●Possible bruising or discomfort at the blood draw site
  • ●Psychological impact of genetic results
  • ●Privacy concerns regarding genetic data

Interfering Factors

  • ●Degraded or low-quality DNA
  • ●Contamination with RNA or proteins
  • ●Insufficient DNA quantity
  • ●PCR amplification errors
  • ●Bioinformatics pipeline variations

Compare With Similar Tests

Test2x150 Hiseq Sequencing- 1 GB
Comparison2x150 Hiseq Sequencing- 1 GB

Frequently Asked Questions

What is 2x150 HiSeq Sequencing?
2x150 HiSeq Sequencing is a next-generation sequencing method that reads DNA fragments of 150 base pairs from both ends, producing paired-end reads. This enhances accuracy and is used for various genetic analyses.
What is the cost of the 2x150 HiSeq Sequencing (1GB) test?
The cost is INR 2500, which is a special discounted price offered by DNA Labs India.
What sample is required for this test?
The test requires extracted DNA. DNA can be extracted from blood or saliva samples.
How long does it take to get results?
The turnaround time is 4 weeks from the date of sample receipt.
Is home sample collection available?
Yes, we offer free home sample collection for online bookings across many cities in India.
What is the difference between 1GB and other sequencing data sizes?
1GB refers to the amount of sequencing data generated. Larger data sizes provide more coverage but at a higher cost. 1GB is suitable for targeted or small-scale sequencing.
Can this test detect all genetic disorders?
No, it can detect variants in the sequenced regions. It may not cover all genomic areas, and some disorders may require other testing methods.
Is fasting required before the test?
No, fasting is not required for this test.
Will I get a report explaining the results?
Yes, you will receive a detailed report with variant classification and clinical significance, along with recommendations.
Is the test covered by insurance?
Insurance coverage is not guaranteed. You may check with your insurance provider for reimbursement options.
What is the accuracy of this sequencing method?
The error rate is less than 0.1%, and Q30 scores are typically above 80%, indicating high accuracy.
Can I use this test for pharmacogenetic testing?
Yes, the data can be used to identify genetic variants that affect drug metabolism and response.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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