A2M Gene Alpha-2-macroglobulin deficiency NGS Genetic Test
Short Name: A2M Gene NGS Test
Also known as: A2M Deficiency Genetic Test, Alpha-2-Macroglobulin Gene Test, A2M NGS Sequencing
A2M Gene Alpha-2-macroglobulin deficiency NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
To diagnose A2M deficiency through genetic analysis, enabling early intervention, risk assessment, and management of related health conditions like arthritis, Alzheimer's, and cancer.
- Test Code
- 1877
- Price
- ₹20,000
- Sample Type
- Blood
- Result Time
- 3 to 4 weeks
- Fasting Required
- No
- Method
- NGS Technology
Sample Collection
Inform the healthcare provider about any medications, medical history, and family history of genetic disorders. Genetic counseling is recommended.
Method: Venipuncture
Laboratory Analysis
Standard blood draw procedure from a vein in the arm using a sterile needle.
Report Delivery
Apply pressure to the puncture site with a cotton ball to prevent bleeding. Keep the area clean.
Timeline: 3 to 4 weeks
Patient Instructions
About This Test
Who Should Get This Test
To diagnose A2M deficiency through genetic analysis, enabling early intervention, risk assessment, and management of related health conditions like arthritis, Alzheimer's, and cancer.
How to Prepare
- Ensure proper labeling of the sample with patient details
- Avoid hemolysis by gentle mixing and proper handling
- Transport the sample at ambient temperature as specified
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Genetic testing for A2M deficiency is crucial for early diagnosis, especially in families with a history of metabolic disorders, enabling proactive management and counseling."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted samples
- Insufficient sample volume
- Incorrect or missing patient information
Understanding Your Results
No pathogenic mutations detected
Normal A2M gene function, deficiency unlikely
Action: Consult with a physician for symptom management if present
Pathogenic mutations detected
Confirmed A2M deficiency, associated with increased health risks
Action: Refer to a genetic counselor and specialist for monitoring and treatment options
If you experience symptoms like joint pain, memory loss, or have a family history of A2M deficiency, consult a genetic counselor or physician for evaluation and testing.
Limitations
- ⚠Detects only known mutations in the A2M gene
- ⚠May not identify all genetic variants or polygenic factors
- ⚠Results require interpretation by a genetic specialist and clinical correlation
Risks & Considerations
- ●Minimal risk from blood draw, such as bruising or infection
- ●Potential psychological impact of genetic results
- ●Risk of misinterpretation without professional guidance
Interfering Factors
- ●Poor sample quality or hemolysis
- ●Contamination during DNA extraction
- ●Inadequate sample volume
Compare With Similar Tests
| Test | A2M Gene Alpha-2-macroglobulin deficiency NGS Genetic Test | Alpha-2-Macroglobulin Serum Test | Alzheimer's Disease Genetic Panel |
|---|---|---|---|
| Comparison | A2M Gene Alpha-2-macroglobulin deficiency NGS Genetic Test |
Frequently Asked Questions
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