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DNA Labs India

ADAM10 Gene Reticulate acropigmentation of Kitamura NGS Genetic Test

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ADAM10 Gene Reticulate acropigmentation of Kitamura NGS Genetic Test

Also known as: Reticulate Acropigmentation of Kitamura, ADAM10-related skin disorder

ADAM10 Gene Reticulate acropigmentation of Kitamura NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

Next-Generation Sequencing (NGS) Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

The purpose of this test is to identify mutations in the ADAM10 gene for the diagnosis of reticulate acropigmentation of Kitamura, enabling confirmatory diagnosis, genetic counseling, and informed management decisions.

Test Code
2469
Price
₹20,000
Sample Type
Blood
Result Time
3 to 4 Weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

No special preparation is required. Provide clinical history and undergo genetic counseling as recommended.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample will be drawn via venipuncture by a trained phlebotomist.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bleeding. Resume normal activities.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Provide clinical history and undergo genetic counseling. No fasting required.
2
During the Test:Blood sample collection via venipuncture.
3
After the Test:Results available in 3 to 4 weeks. Genetic counseling recommended for interpretation.

About This Test

Who Should Get This Test

The purpose of this test is to identify mutations in the ADAM10 gene for the diagnosis of reticulate acropigmentation of Kitamura, enabling confirmatory diagnosis, genetic counseling, and informed management decisions.

How to Prepare

  • Ensure proper patient identification
  • Use sterile equipment and follow aseptic techniques
  • Label samples accurately with patient details

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"This test is crucial for confirming diagnosis and guiding management of reticulate acropigmentation of Kitamura, especially for genetic counseling and family planning."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood
Collection MethodVenipuncture

Sample Stability

Blood samples are stable for 24 hours at room temperature
For longer storage, refrigerate at 2-8°C
Sample Rejection Criteria:
  • Hemolyzed or clotted samples
  • Insufficient sample volume
  • Improper labeling or documentation

Understanding Your Results

Results indicate the presence or absence of mutations in the ADAM10 gene. Positive results confirm the diagnosis, while negative results may require further clinical evaluation.
Positive: Pathogenic variant detected, confirming diagnosis of reticulate acropigmentation of Kitamura.
Negative: No pathogenic variant detected; consider other diagnoses or repeat testing if clinically indicated.
Variant of Uncertain Significance (VUS): Further testing and genetic counseling recommended.
⚠️ When to Consult a Doctor:

Consult a doctor if you have symptoms of reticulate hyperpigmentation, a family history of the disorder, or after receiving test results for management and genetic counseling.

Limitations

  • ⚠May not detect all types of mutations, such as large deletions or duplications
  • ⚠Requires genetic counseling for interpretation of variants of uncertain significance
  • ⚠Results are for diagnostic purposes and should be correlated with clinical findings

Risks & Considerations

  • ●Minimal risks from blood draw, such as bruising or infection
  • ●Psychological impact of genetic results; counseling advised

Interfering Factors

  • ●Poor sample quality or hemolysis
  • ●Contamination during sample collection or processing
  • ●Insufficient sample volume

Frequently Asked Questions

What is ADAM10 Gene Reticulate Acropigmentation of Kitamura?
It is a rare genetic skin disorder characterized by reticulated hyperpigmentation on the hands and feet, caused by mutations in the ADAM10 gene.
What are the symptoms of this condition?
Symptoms include net-like hyperpigmentation on extremities, which may spread over time, and sometimes small white spots (guttate hypomelanosis). Symptoms often appear in infancy or childhood.
How is the condition diagnosed?
Diagnosis is based on clinical presentation and confirmed through genetic testing using Next-Generation Sequencing (NGS) to identify mutations in the ADAM10 gene.
What is the NGS Genetic Test?
NGS (Next-Generation Sequencing) is a advanced genetic test that sequences the entire ADAM10 gene to accurately detect mutations associated with the disorder.
What is the cost of the test in India?
The cost of the ADAM10 Gene Reticulate Acropigmentation NGS Genetic Test at DNA Labs India is INR 20,000.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for this test across many cities in India.
How long does it take to get results?
Results are typically available in 3 to 4 weeks after sample collection.
What should I do if the test is positive?
A positive result confirms the diagnosis. Consult a healthcare provider for management options and genetic counseling for family planning.
Is the test covered by insurance?
Coverage varies by insurance plan. It is advisable to check with your provider. DNA Labs India offers competitive pricing.
Can the test be done for prenatal diagnosis?
Prenatal testing may be possible through genetic counseling, but this test is typically for postnatal diagnosis. Consult a genetic specialist for options.
What are the limitations of the test?
Limitations include potential inability to detect all mutation types and the need for genetic counseling to interpret variants of uncertain significance.
How accurate is the NGS test?
NGS is highly accurate for detecting mutations in the ADAM10 gene, but accuracy depends on sample quality and laboratory standards. DNA Labs India ensures reliable results.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

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Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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