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DNA Labs India

AIFM1 Gene Deafness, X-linked type 5 NGS Genetic Test

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AIFM1 Gene Deafness, X-linked type 5 NGS Genetic Test

Short Name: AIFM1 Deafness NGS Test

Also known as: X-linked deafness type 5, AIFM1-related hearing loss

AIFM1 Gene Deafness, X-linked type 5 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood samples. Results in 3 to 4 weeks from sample receipt. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

The purpose of this test is to detect mutations in the AIFM1 gene that cause X-linked type 5 deafness, enabling accurate diagnosis and management of hereditary hearing loss.

Test Code
4765
Price
₹20,000
Sample Type
Blood
Result Time
3 to 4 weeks from sample receipt
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

No specific preparation required. Provide clinical history and family pedigree.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample will be drawn from a vein in your arm by a trained phlebotomist.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bleeding. Resume normal activities.

Timeline: 3 to 4 weeks from sample receipt

Patient Instructions

1
Before the Test:Genetic counseling recommended to understand implications and family history.
2
During the Test:The test involves DNA extraction and sequencing using Next-Generation Sequencing technology.
3
After the Test:Results will be available in 3-4 weeks. Follow-up with a genetic counselor for interpretation.

About This Test

Who Should Get This Test

The purpose of this test is to detect mutations in the AIFM1 gene that cause X-linked type 5 deafness, enabling accurate diagnosis and management of hereditary hearing loss.

How to Prepare

  • Bring identification and prescription
  • Inform about any medications or health conditions
  • Ensure sample is collected in a sterile environment

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Genetic testing for AIFM1 gene mutations is crucial for early intervention in X-linked deafness, especially in families with a history of hearing loss."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood
Sample Volume5 ml
ContainerEDTA tube
Collection MethodVenipuncture

Sample Stability

Blood sample stable at room temperature for 24 hours
Refrigerate at 2-8°C for up to 7 days
Sample Rejection Criteria:
  • Hemolyzed sample
  • Insufficient volume
  • Incorrect container or labeling

Understanding Your Results

Results indicate the presence or absence of pathogenic variants in the AIFM1 gene. Consult a geneticist for detailed interpretation and counseling.
Normal result: No pathogenic variants detected, low risk for AIFM1-related deafness
Positive result: Pathogenic variant detected, confirm with family testing and clinical correlation
Variant of uncertain significance: Further testing or family studies may be recommended
⚠️ When to Consult a Doctor:

If you have a family history of deafness or experience symptoms of hearing loss, consult an ENT specialist or geneticist for evaluation and management.

Limitations

  • ⚠May not detect all types of mutations
  • ⚠Requires genetic counseling for interpretation
  • ⚠Results should be correlated with clinical findings

Risks & Considerations

  • ●Minimal risk from blood draw: bruising, infection
  • ●Psychological impact of genetic results; counseling available

Interfering Factors

  • ●Sample contamination
  • ●Improper sample storage
  • ●Recent blood transfusion

Compare With Similar Tests

TestAIFM1 Gene Deafness, X-linked type 5 NGS Genetic TestGJB2 Gene TestSLC26A4 Gene TestComprehensive Deafness Panel
ComparisonAIFM1 Gene Deafness, X-linked type 5 NGS Genetic Test

Frequently Asked Questions

What is AIFM1 gene deafness?
AIFM1 gene deafness is a genetic condition caused by mutations in the AIFM1 gene, leading to X-linked type 5 hearing loss.
How is the NGS genetic test performed?
The test involves sequencing the AIFM1 gene using Next-Generation Sequencing technology to detect mutations from a blood sample.
What is the cost of the AIFM1 gene deafness test?
The test costs INR 20,000 at DNA Labs India, with free home sample collection available.
Is home sample collection available?
Yes, free home sample collection is available for online bookings across India.
How long does it take to get the test results?
Results are typically available within 3 to 4 weeks after sample receipt.
Who should consider getting this test?
Individuals with a family history of X-linked deafness or symptoms of progressive hearing loss should consider this test.
What are the common symptoms of AIFM1 gene deafness?
Symptoms include difficulty hearing high-pitched sounds, trouble understanding speech, progressive hearing loss, and tinnitus.
How accurate is the NGS test for AIFM1 gene mutations?
NGS is highly accurate for detecting genetic mutations, but results should be interpreted by a qualified geneticist.
Can this test be done during pregnancy?
Yes, but genetic counseling is recommended to discuss implications for the pregnancy and family.
What does a positive test result mean?
A positive result indicates a pathogenic mutation in the AIFM1 gene, confirming the diagnosis of X-linked deafness and guiding management.
Is genetic counseling provided with the test?
Yes, DNA Labs India offers genetic counseling to help interpret results and provide support.
Are there any risks associated with the test?
The test involves a blood draw, which has minimal risks such as bruising or infection; psychological support is available.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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