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DNA Labs India

Alpha-2-Macroglobulin Test

DNA Labs India | ISO 9001:2015 Certified

Alpha-2-Macroglobulin Test

Short Name: A2M Test

Also known as: A2M Test, Alpha-2-Macroglobulin Blood Test

Alpha-2-Macroglobulin Test test available at DNA Labs India for ₹4,000. Uses Nephelometry on Serum samples. Results in Reports are typically available within 10 days after sample collection.. Free home collection in 300+ cities across India.

Blood TestAll Ages🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

To diagnose Alpha-2-Macroglobulin deficiency and aid in the evaluation of joint disorders like osteoarthritis and rheumatoid arthritis, as well as liver and kidney conditions.

Test Code
87
Price
₹4,000
Sample Type
Serum
Result Time
Reports are typically available within 10 days after sample collection.
Fasting Required
Yes
Method
Nephelometry
Step 1

Sample Collection

Overnight fasting is preferred.

Method: Venipuncture

Step 2

Laboratory Analysis

A small blood sample is drawn from a vein in the arm.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bruising.

Timeline: Reports are typically available within 10 days after sample collection.

Patient Instructions

1
Before the Test:Fasting is preferred overnight before the test.
2
During the Test:A blood sample will be collected via venipuncture.
3
After the Test:You can resume normal activities immediately after sample collection.

About This Test

Who Should Get This Test

To diagnose Alpha-2-Macroglobulin deficiency and aid in the evaluation of joint disorders like osteoarthritis and rheumatoid arthritis, as well as liver and kidney conditions.

How to Prepare

  • Overnight fasting preferred
  • Avoid hemolysis
  • 2 mL serum from SST
  • Ship refrigerated or frozen

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeSerum
Sample Volume2 mL (1 mL min.)
ContainerSerum Separator Tube (SST)
Collection MethodVenipuncture

Sample Stability

Room Temperature: 24 hours
Refrigerator: 7 days
Frozen: 90 days
Sample Rejection Criteria:
  • Hemolyzed samples

Understanding Your Results

Results indicate the level of Alpha-2-Macroglobulin in the blood. Abnormal levels may suggest deficiency or other underlying conditions.
Low A2M levels may indicate deficiency associated with joint disorders or liver/kidney issues.
Normal levels suggest adequate A2M function.
Consult a physician for accurate diagnosis and further tests.
⚠️ When to Consult a Doctor:

If you experience persistent joint pain, stiffness, or other symptoms mentioned, consult a healthcare provider for evaluation and to discuss if this test is needed.

Risks & Considerations

  • ●Minor bruising at the puncture site
  • ●Rare risk of infection
  • ●Lightheadedness or dizziness

Interfering Factors

  • ●Hemolyzed samples

Frequently Asked Questions

What is Alpha-2-Macroglobulin?
Alpha-2-Macroglobulin is a protein in the blood that plays a role in the immune system by helping to clear damaged cells and tissues.
Why is the A2M test done?
The test is done to measure A2M levels and diagnose deficiencies that may be linked to joint disorders like osteoarthritis or rheumatoid arthritis.
What are the symptoms of A2M deficiency?
Symptoms include joint pain, stiffness, reduced range of motion, swelling, and difficulty in daily activities.
How is the A2M test performed?
It is a simple blood test where a small sample is drawn from the arm and analyzed in the lab using nephelometry.
What is the cost of the A2M test at DNA Labs India?
The cost is INR 4000, which includes home sample collection in many cities.
Is fasting required for the A2M test?
Overnight fasting is preferred but not mandatory; follow lab instructions.
How long does it take to get A2M test results?
Results are usually available within 10 days after sample collection.
Is the A2M test covered by insurance?
Yes, it is covered by some insurance plans. Check with your provider for eligibility.
What does a low A2M level indicate?
Low levels may indicate A2M deficiency, which can be associated with joint problems or liver/kidney disorders.
What are the risks of the A2M test?
Risks are minimal and may include minor bruising or dizziness at the blood draw site.
Can I get a home sample collection for the A2M test?
Yes, DNA Labs India offers free home sample collection for online bookings in many cities across India.
What conditions can the A2M test help diagnose?
It helps diagnose A2M deficiency, which is linked to osteoarthritis, rheumatoid arthritis, and disorders of the liver and kidney.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.
For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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