ANOS1 Gene Kallmann syndrome type 1 NGS Genetic Test
Short Name: ANOS1 Gene Test
Also known as: Kallmann syndrome type 1 genetic test, ANOS1 mutation analysis, X-linked Kallmann syndrome test
ANOS1 Gene Kallmann syndrome type 1 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of the ANOS1 Gene Kallmann Syndrome Type 1 NGS Genetic Test is to confirm a clinical diagnosis of Kallmann syndrome type 1 by identifying pathogenic mutations in the ANOS1 gene. This enables targeted treatment, genetic counseling, and family planning guidance for affected individuals and their families.
- Test Code
- 2606
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No specific preparation required. Provide clinical history and family pedigree chart as advised during genetic counseling.
Method: Venipuncture or finger-prick
Laboratory Analysis
A blood sample will be collected via venipuncture or a drop on an FTA card. The procedure is quick and minimally invasive.
Report Delivery
Apply pressure to the puncture site to prevent bruising. Resume normal activities immediately.
Timeline: 3 to 4 weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the ANOS1 Gene Kallmann Syndrome Type 1 NGS Genetic Test is to confirm a clinical diagnosis of Kallmann syndrome type 1 by identifying pathogenic mutations in the ANOS1 gene. This enables targeted treatment, genetic counseling, and family planning guidance for affected individuals and their families.
How to Prepare
- Ensure proper identification of the patient
- Use sterile collection equipment
- Label samples correctly with patient details
- Transport samples at ambient temperature as specified
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Early genetic diagnosis of Kallmann syndrome type 1 allows for timely hormone therapy and management of fertility issues, improving patient outcomes."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood samples
- Insufficient sample volume
- Incorrectly labeled or unlabeled samples
Understanding Your Results
Positive for pathogenic variant
Confirms diagnosis of Kallmann syndrome type 1. Genetic counseling and treatment planning recommended.
Negative for pathogenic variant
No mutation detected in the ANOS1 gene. Clinical symptoms may be due to other genetic or non-genetic causes.
Variant of uncertain significance (VUS)
A genetic change was found, but its clinical significance is unknown. Further testing and family studies may be needed.
Consult a healthcare provider if you or your child experiences symptoms such as lack of smell, delayed puberty, or infertility. Early diagnosis can guide appropriate management.
Limitations
- ⚠May not detect all types of genetic variants, such as large deletions or intronic mutations
- ⚠Results require clinical correlation and genetic counseling
- ⚠Does not rule out other genetic causes of hypogonadotropic hypogonadism
Risks & Considerations
- ●Minor pain or bruising at the blood draw site
- ●Very low risk of infection
- ●Psychological impact of genetic results
Interfering Factors
- ●Sample contamination
- ●Degraded DNA quality
- ●Incorrect sample storage or handling
Frequently Asked Questions
What is Kallmann syndrome type 1?
How is the ANOS1 gene test performed?
Who should consider this genetic test?
What is the cost of the test in India?
Is home sample collection available?
How long does it take to get results?
What does a positive result mean?
Can females have Kallmann syndrome type 1?
Is genetic counseling required before testing?
What treatments are available after diagnosis?
Are there any risks associated with the test?
Is the test covered by insurance?
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₹20,000Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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