APOA2 Gene Apolipoprotein A-II deficiency NGS Genetic Test
Short Name: APOA2 Deficiency NGS Test
Also known as: Apolipoprotein A-II Deficiency Test, APOA2 Mutation Analysis, APOA2 Gene Sequencing
APOA2 Gene Apolipoprotein A-II deficiency NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
To identify mutations in the APOA2 gene that cause Apolipoprotein A-II deficiency, aiding in the diagnosis of genetic hypercholesterolemia and assessing cardiovascular risk for personalized treatment.
- Test Code
- 4631
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No special preparation is required. Provide clinical history and family pedigree information.
Method: Venipuncture or finger-prick
Laboratory Analysis
A trained phlebotomist will collect a blood sample via venipuncture or a drop on an FTA card.
Report Delivery
Apply pressure to the puncture site to prevent bruising. Store samples as instructed.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
To identify mutations in the APOA2 gene that cause Apolipoprotein A-II deficiency, aiding in the diagnosis of genetic hypercholesterolemia and assessing cardiovascular risk for personalized treatment.
How to Prepare
- Ensure patient identification is correct
- Use sterile collection equipment
- Label samples accurately
- Transport samples at ambient temperature
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Genetic testing for APOA2 deficiency can identify individuals at higher risk for cardiovascular diseases, enabling early lifestyle and medical interventions."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or lipemic samples
- Insufficient sample volume
- Improperly labeled or contaminated samples
Understanding Your Results
No mutation detected
Normal APOA2 gene; low genetic risk for deficiency
Pathogenic variant found
Confirmed APOA2 deficiency; increased cardiovascular risk
Variant of uncertain significance (VUS)
Further testing and clinical correlation needed
Consult a geneticist or cardiologist if results show pathogenic variants or if there is a strong family history of heart disease.
Limitations
- ⚠May not detect all possible genetic variants
- ⚠Results require interpretation by a genetic counselor
- ⚠Does not replace comprehensive lipid profiling
- ⚠Limited to APOA2 gene analysis; other genes may be involved
Risks & Considerations
- ●Minor bruising or pain at puncture site
- ●Rare risk of infection
- ●Psychological impact of genetic results
Interfering Factors
- ●Sample contamination or degradation
- ●Recent blood transfusions
- ●Inadequate sample volume
- ●Use of certain medications affecting lipid metabolism
Compare With Similar Tests
| Test | APOA2 Gene Apolipoprotein A-II deficiency NGS Genetic Test | Lipid Profile Test | APOB Gene Test | LDLR Gene Test | PCSK9 Gene Test |
|---|---|---|---|---|---|
| Comparison | APOA2 Gene Apolipoprotein A-II deficiency NGS Genetic Test |
Frequently Asked Questions
What is the APOA2 Gene Apolipoprotein A-II Deficiency NGS Genetic Test?
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Can this test diagnose heart disease?
Is genetic counseling recommended?
What if a variant of uncertain significance (VUS) is found?
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