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APOE Gene Lipoprotein glomerulopathy NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

APOE Gene Lipoprotein glomerulopathy NGS Genetic Test

Short Name: APOE LPG NGS Test

Also known as: APOE-related glomerulopathy, Lipoprotein glomerulopathy genetic test

APOE Gene Lipoprotein glomerulopathy NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To detect pathogenic mutations in the APOE gene responsible for lipoprotein glomerulopathy, enabling accurate diagnosis, risk assessment, and informed clinical management.

Test Code
2614
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks
Fasting Required
No
Method
Next Generation Sequencing (NGS)
Step 1

Sample Collection

No specific preparation required. Ensure clinical history and genetic counseling session are completed.

Method: Venipuncture or finger-prick

Step 2

Laboratory Analysis

A blood sample will be drawn from a vein in the arm or a finger-prick for FTA card collection.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bleeding. Resume normal activities.

Timeline: 3 to 4 weeks

Patient Instructions

1
Before the Test:Complete genetic counseling session and provide detailed clinical history.
2
During the Test:Blood sample collection via venipuncture or finger-prick; procedure takes about 10-15 minutes.
3
After the Test:No restrictions; monitor puncture site for any discomfort.

About This Test

Who Should Get This Test

To detect pathogenic mutations in the APOE gene responsible for lipoprotein glomerulopathy, enabling accurate diagnosis, risk assessment, and informed clinical management.

How to Prepare

  • Provide accurate clinical and family history
  • Ensure sample is labeled correctly
  • Avoid hemolysis during blood draw

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"This genetic test is vital for diagnosing hereditary kidney disorders, enabling early intervention and family planning counseling."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume5-10 ml blood
ContainerEDTA tube or FTA card
Collection MethodVenipuncture or finger-prick

Sample Stability

Blood samples stable for 48 hours at room temperature
Extracted DNA stable for longer periods if stored properly
Sample Rejection Criteria:
  • Hemolyzed or clotted blood samples
  • Insufficient sample volume
  • Improperly labeled or contaminated samples

Understanding Your Results

Results indicate the presence or absence of pathogenic mutations in the APOE gene. A positive result confirms genetic predisposition to lipoprotein glomerulopathy, while a negative result suggests no known mutations, but does not rule out other causes.
📊

Positive for pathogenic variant

Confirms diagnosis of APOE gene lipoprotein glomerulopathy. Genetic counseling and nephrology consultation recommended.

📊

Negative for pathogenic variant

No known mutations detected. Clinical correlation and further testing may be needed if symptoms persist.

📊

Variant of uncertain significance

Genetic variant found but clinical significance unknown. Repeat testing or family studies may be advised.

⚠️ When to Consult a Doctor:

Consult a nephrologist or genetic specialist if test results are positive, or if symptoms like proteinuria, edema, or hypertension persist despite negative results.

Limitations

  • ⚠May not detect all possible genetic variants or novel mutations
  • ⚠Requires genetic counseling for proper interpretation
  • ⚠Results should be correlated with clinical findings and other tests

Risks & Considerations

  • ●Minimal risk from blood draw, such as bruising or infection
  • ●Psychological impact of genetic results; counseling recommended

Interfering Factors

  • ●Sample contamination during collection or transport
  • ●Improper storage of blood or DNA samples
  • ●Recent blood transfusions may affect DNA analysis

Compare With Similar Tests

TestAPOE Gene Lipoprotein glomerulopathy NGS Genetic TestAPOE Genotyping TestKidney Biopsy
ComparisonAPOE Gene Lipoprotein glomerulopathy NGS Genetic Test

Frequently Asked Questions

What is APOE Gene Lipoprotein Glomerulopathy?
It is a rare genetic disorder caused by mutations in the APOE gene, leading to lipid accumulation in the kidneys and causing glomerular damage.
What are the symptoms of this condition?
Symptoms include proteinuria, edema, high blood pressure, reduced kidney function, and chronic kidney disease.
How is the NGS Genetic Test performed?
The test uses Next Generation Sequencing to analyze the APOE gene from a blood or DNA sample, detecting mutations accurately.
What is the cost of the test?
The test costs INR 20000, with free home sample collection available across India.
Is home sample collection available?
Yes, free home sample collection is offered for online bookings in numerous cities across India.
How long does it take to get the results?
Results are typically available within 3 to 4 weeks after sample collection.
What do the test results mean?
A positive result indicates a pathogenic mutation in the APOE gene, confirming the disorder. A negative result means no known mutations were detected.
Is genetic counseling required before the test?
Yes, a genetic counseling session is recommended to understand the implications and draw a family pedigree chart.
Can this test be used for prenatal diagnosis?
It may be used for carrier testing or prenatal diagnosis in high-risk families, but consultation with a genetic specialist is essential.
What are the risks of the test?
Risks are minimal, primarily related to blood draw, such as bruising. Psychological impact may occur, so counseling is advised.
How accurate is the NGS Genetic Test?
The test is highly accurate with advanced NGS technology, capable of detecting even small genetic variations.
What should I do if the test is positive?
Consult a nephrologist or genetic specialist for management, treatment options, and family planning advice.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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