Aptamer Sequencing and Analysis Test
Short Name: Aptamer Seq
Also known as: Aptamer NGS, Aptamer Sequencing
Aptamer Sequencing and Analysis Test test available at DNA Labs India for ₹30,000. Uses Next-Generation Sequencing (NGS), Bioinformatics Analysis on Extracted DNA samples. Results in Reports are delivered within 8 weeks from sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of aptamer sequencing and analysis is to determine the nucleotide sequences of aptamers within a library, identify those with high binding affinity to a specific target, and provide quantitative data on their enrichment. This information is crucial for selecting lead aptamer candidates for further development in diagnostics, therapeutics, and biosensing applications.
- Test Code
- 6358
- CPT Code
- 0000A
- ICD Code
- Z00.00
- Price
- ₹30,000
- Sample Type
- Extracted DNA
- Result Time
- Reports are delivered within 8 weeks from sample receipt.
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS), Bioinformatics Analysis
Sample Collection
No special preparation is required. Ensure the extracted DNA sample is of high quality and free from contaminants.
Method: Blood or extracted DNA
Laboratory Analysis
Sample collection is performed by trained phlebotomists. For extracted DNA, provide the sample in a sterile, labeled tube.
Report Delivery
The sample should be transported to the laboratory at the earliest, preferably on ice or at 4°C. No specific aftercare is needed.
Timeline: Reports are delivered within 8 weeks from sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of aptamer sequencing and analysis is to determine the nucleotide sequences of aptamers within a library, identify those with high binding affinity to a specific target, and provide quantitative data on their enrichment. This information is crucial for selecting lead aptamer candidates for further development in diagnostics, therapeutics, and biosensing applications.
How to Prepare
- For blood collection, use EDTA or citrate tubes.
- For extracted DNA, ensure concentration is at least 50 ng/µL.
- Label the sample with patient ID and date.
- Maintain cold chain during transport.
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"Aptamer sequencing is a powerful tool for identifying high-affinity binders. Our analysis pipeline ensures accurate sequence identification and quality control, supporting research and diagnostic applications."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed blood samples
- Insufficient DNA quantity (<1 µg)
- Degraded DNA (low molecular weight)
- Improper labeling
Understanding Your Results
Sequences with fold change >2 are considered significantly enriched and may represent high-affinity aptamers.
A high diversity indicates a complex library, while low diversity may suggest over-amplification or loss of variants.
Optimal GC content (40-60%) ensures stable secondary structures and efficient amplification.
If you are developing aptamer-based diagnostics or therapeutics, consult with a molecular biologist or geneticist to interpret the sequencing results and plan next steps. For clinical applications, discuss with a qualified medical professional.
Limitations
- ⚠Requires high-quality extracted DNA
- ⚠Bioinformatics analysis may not predict binding affinity accurately
- ⚠Results depend on library complexity and SELEX enrichment
- ⚠Not a diagnostic test for any specific disease
Risks & Considerations
- ●No significant risks associated with blood draw
- ●Possible bruising at venipuncture site
- ●Rare infection if proper hygiene is not maintained
Interfering Factors
- ●Contamination with genomic DNA
- ●Degraded RNA/DNA samples
- ●PCR amplification bias
- ●Incomplete adapter ligation
- ●Low sample concentration
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Frequently Asked Questions
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Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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