ASB10 Gene Glaucoma, Open Angle Type 1F NGS Genetic Test
Short Name: ASB10 Glaucoma NGS Test
Also known as: ASB10 Gene Test, Open Angle Glaucoma Type 1F Genetic Test, ASB10 NGS Genetic Analysis
ASB10 Gene Glaucoma, Open Angle Type 1F NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood / Extracted DNA / One drop blood on FTA card samples. Results in Reports are released within 3 to 4 weeks after the sample reaches the laboratory and sequencing is completed.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of this test is to identify pathogenic or likely pathogenic mutations in the ASB10 gene associated with Glaucoma, Open Angle Type 1F. This information helps confirm a genetic cause, support clinical diagnosis, and inform family members about their potential risk for developing glaucoma.
- Test Code
- 3833
- Price
- ₹20,000
- Sample Type
- Blood / Extracted DNA / One drop blood on FTA card
- Result Time
- Reports are released within 3 to 4 weeks after the sample reaches the laboratory and sequencing is completed.
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No fasting is required. A genetic counselling session is recommended before the test to document clinical history and draw a pedigree chart of family members affected with Glaucoma, Open Angle Type 1F.
Method: Peripheral venous blood draw or FTA card spotting
Laboratory Analysis
A peripheral blood sample will be collected in an EDTA vacutainer. In some cases, a single drop of blood may be placed on an FTA card. The procedure is quick and safe.
Report Delivery
No special precautions are required after sample collection. You can resume normal activities and medications as advised by your doctor.
Timeline: Reports are released within 3 to 4 weeks after the sample reaches the laboratory and sequencing is completed.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to identify pathogenic or likely pathogenic mutations in the ASB10 gene associated with Glaucoma, Open Angle Type 1F. This information helps confirm a genetic cause, support clinical diagnosis, and inform family members about their potential risk for developing glaucoma.
How to Prepare
- Blood sample should be collected in an EDTA vacutainer.
- FTA card should be labeled with patient name and sample ID.
- The sample should be transported to the laboratory at ambient temperature.
- Plasma or serum samples are not suitable for this NGS genetic test.
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Genetic counselling is strongly recommended before and after this test. A shared decision between the ophthalmologist and clinical geneticist will help interpret the result in the context of the patient's complete medical history and family pedigree."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Inappropriate or unlabeled sample
- Clotted blood sample
- Hemolyzed or frozen whole blood
- Incomplete test requisition form without clinical history
- Incorrect sample type such as serum or plasma
Understanding Your Results
The ASB10 variant is disease-causing and strongly supports the diagnosis of Glaucoma, Open Angle Type 1F.
The variant is highly likely to cause disease; clinical correlation and family evaluation are recommended.
The variant has unclear disease association; additional family segregation testing may help clarify.
The variant is not considered disease-causing for Glaucoma, Open Angle Type 1F.
If you receive a positive result or a Variant of Uncertain Significance, consult your ophthalmologist and clinical geneticist for personalised surveillance, treatment planning, and family risk assessment.
Limitations
- ⚠This test analyzes the ASB10 gene only and does not rule out other glaucoma-related genetic causes.
- ⚠Rare deep intronic mutations, large deletions, duplications, and structural variants may not be detected by standard NGS analysis.
- ⚠A Variant of Uncertain Significance (VUS) may require additional family studies to determine its clinical relevance.
- ⚠Test results must not be used alone for a clinical diagnosis; correlation with ophthalmological examination is essential.
Risks & Considerations
- ●Mild pain or discomfort at the puncture site
- ●Small bruise or swelling after blood collection
- ●Rare lightheadedness or fainting during venipuncture
- ●No additional significant physical risks; psychological implications of genetic information may exist
Interfering Factors
- ●No food or medication interference is expected for DNA analysis.
- ●Poor quality or degraded DNA may affect sequencing success and require repeat testing.
- ●Incomplete clinical history or family pedigree can limit interpretation.
- ●Variants of uncertain significance may not provide a definitive clinical answer.
Compare With Similar Tests
| Test | ASB10 Gene Glaucoma, Open Angle Type 1F NGS Genetic Test | ||
|---|---|---|---|
| Comparison | ASB10 Gene Glaucoma, Open Angle Type 1F NGS Genetic Test |
Frequently Asked Questions
What is the cost of the ASB10 gene glaucoma, open angle type 1F NGS genetic test in India?
What type of sample is required for this genetic test?
Is fasting required before taking this test?
How long will test reports take?
What does a positive test result mean?
Who should consider taking this genetic test?
Can this test predict when glaucoma symptoms will start?
How is this test different from a regular eye check-up?
Why is genetic counselling important before and after this test?
Does the test require any special medication preparation?
Can this test be done during pregnancy?
Will home sample collection be provided for this test?
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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