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DNA Labs India

Aspirin Resistance (11-Dehydrothromboxane B2) Test

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Aspirin Resistance (11-Dehydrothromboxane B2) Test

Also known as: Aspirin Non-Response, Aspirin Therapy Resistance

Aspirin Resistance (11-Dehydrothromboxane B2) Test test available at DNA Labs India for ₹20,000. Uses Immunoassay on Urine samples. Results in Sample by 7th of the month; report after 2-3 weeks. Free home collection in 300+ cities across India.

Laboratory TestAdults🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Ramarao Paidisetty

Dr Ramarao Paidisetty

Consultant Biochemist · Reg: 21504

Last reviewed: September 7, 2026

Overview

To diagnose aspirin resistance and guide antiplatelet therapy in patients at risk of cardiovascular events, ensuring optimal treatment outcomes.

Test Code
176
Price
₹20,000
Sample Type
Urine
Result Time
Sample by 7th of the month; report after 2-3 weeks
Fasting Required
No
Method
Immunoassay
Step 1

Sample Collection

Continue aspirin therapy as prescribed by your doctor. No special fasting is required, but avoid intense physical activity before collection.

Method: Urine collection

Step 2

Laboratory Analysis

Collect a mid-stream urine sample in the provided special vacutainer tube. Ensure the tube is properly labeled.

Step 3

Report Delivery

Store the sample at room temperature for up to 8 hours, refrigerate for up to 7 days, or freeze for up to 30 days. Ship refrigerated or frozen.

Timeline: Sample by 7th of the month; report after 2-3 weeks

Patient Instructions

1
Before the Test:Continue aspirin as directed. No fasting required.
2
During the Test:Urine collection at home or lab. Non-invasive procedure.
3
After the Test:Results available online after 2-3 weeks. Follow-up with physician advised.

About This Test

Who Should Get This Test

To diagnose aspirin resistance and guide antiplatelet therapy in patients at risk of cardiovascular events, ensuring optimal treatment outcomes.

How to Prepare

  • Use the special culture vacutainer tube available from LPL.
  • Collect 5 mL of urine (minimum 4 mL).
  • Complete and submit the Test Send Out Consent Form (Form 35).
  • Ship refrigerated or frozen to maintain sample integrity.

Doctor's Notes

Reviewed by — MBBS, MD (Biochemistry) · Reg. No. 21504

"This test is essential for assessing aspirin efficacy in patients with cardiovascular disease, helping to prevent recurrent events by guiding alternative therapies."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeUrine
Sample Volume5 mL (4 mL min.)
ContainerSpecial culture vacutainer tube available from LPL
Collection MethodUrine collection

Sample Stability

Room Temperature: 8 hours
Refrigerator (2-8°C): 7 days
Frozen (-20°C): 30 days
Sample Rejection Criteria:
  • Insufficient sample volume
  • Improper container or labeling
  • Hemolyzed or contaminated sample
  • Missing Consent Form (Form 35)

Understanding Your Results

Results indicate the level of aspirin resistance based on urinary 11-dehydrothromboxane B2. Consult a healthcare provider for accurate interpretation.
Low levels (< 1000 ng/mmol creatinine): Suggest effective aspirin therapy.
High levels (≥ 1000 ng/mmol creatinine): Indicate possible aspirin resistance, requiring further evaluation.
Borderline levels may need repeat testing or correlation with clinical symptoms.
⚠️ When to Consult a Doctor:

If test results indicate high levels of 11-dehydrothromboxane B2, or if you experience symptoms like chest pain or fatigue despite aspirin therapy, consult your cardiologist immediately.

Limitations

  • ⚠Results may vary based on individual metabolism and adherence to aspirin therapy
  • ⚠Not a standalone diagnostic tool; should be correlated with clinical assessment
  • ⚠Lab-specific reference ranges may apply

Risks & Considerations

  • ●Minimal risk as it involves urine collection; no significant risks.

Interfering Factors

  • ●Certain medications like NSAIDs or anticoagulants
  • ●Renal impairment affecting metabolite excretion
  • ●Improper sample collection or storage
  • ●Recent aspirin intake variations

Compare With Similar Tests

TestAspirin Resistance (11-Dehydrothromboxane B2) TestPlatelet Function AssayThromboxane B2 Serum TestVerifyNow Aspirin Test
ComparisonAspirin Resistance (11-Dehydrothromboxane B2) TestMeasures platelet aggregation directly, while this test uses a metabolite.Serum-based vs. urine-based; different sensitivities.Point-of-care test vs. laboratory immunoassay.

Frequently Asked Questions

What is aspirin resistance?
Aspirin resistance is a condition where aspirin does not effectively inhibit platelet aggregation, reducing its protective effects against cardiovascular events.
Who should get the Aspirin Resistance Test?
Patients on aspirin therapy for heart disease, those with recurrent events, or individuals suspected of non-response should consider this test.
How is the test performed?
It measures 11-dehydrothromboxane B2 in urine using immunoassay. A urine sample is collected and sent to the lab.
What does a high level of 11-dehydrothromboxane B2 indicate?
High levels suggest that aspirin is not adequately suppressing thromboxane production, indicating possible aspirin resistance.
Is fasting required for this test?
No, fasting is not required. Continue your regular diet and medications as prescribed.
How long does it take to get results?
Results are typically available within 2-3 weeks after sample collection.
Is home sample collection available?
Yes, DNA Labs India offers free home collection for this test in many cities across India.
What should I do if I have aspirin resistance?
Consult your cardiologist to discuss alternative antiplatelet therapies or adjust your treatment plan.
Are there any risks associated with this test?
The test involves urine collection, which is non-invasive and carries minimal risk.
Can other medications affect the test results?
Yes, drugs like NSAIDs or anticoagulants may interfere. Inform your doctor about all medications.
What is the cost of the test?
The cost at DNA Labs India is INR 20000, inclusive of sample collection and report.
How do I prepare for the test?
Continue aspirin therapy, use the provided urine container, and submit the mandatory Consent Form (Form 35).
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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