ATAC Sequencing and Analysis Test
Short Name: ATAC-Seq
Also known as: ATAC-seq, Assay for Transposase-Accessible Chromatin with high-throughput sequencing
ATAC Sequencing and Analysis Test test available at DNA Labs India for ₹60,000. Uses ATAC-seq (Assay for Transposase-Accessible Chromatin using sequencing) on Extracted DNA samples. Results in Results are typically available within 10 weeks after the sample is received at the lab.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The primary purpose of ATAC sequencing is to assess chromatin accessibility, which reflects the regulatory landscape of the genome. This test helps identify active regulatory elements, transcription factor binding sites, and nucleosome positioning. It is used to understand gene expression regulation, identify disease-associated epigenetic changes, and discover potential biomarkers. In clinical settings, ATAC-seq can aid in diagnosing genetic disorders, characterizing tumors, and guiding targeted therapies.
- Test Code
- 6362
- CPT Code
- 81479
- ICD Code
- Z01.89
- Price
- ₹60,000
- Sample Type
- Extracted DNA
- Result Time
- Results are typically available within 10 weeks after the sample is received at the lab.
- Fasting Required
- No
- Method
- ATAC-seq (Assay for Transposase-Accessible Chromatin using sequencing)
Sample Collection
No special preparation is required. However, if a blood sample is being collected, inform your doctor about any medications you are taking.
Method: Blood or tissue sample (DNA extraction performed at lab)
Laboratory Analysis
A blood sample will be drawn from a vein in your arm. For tissue samples, a biopsy may be performed. The procedure is routine and minimally invasive.
Report Delivery
You can resume normal activities immediately. If you experience any unusual symptoms, contact your healthcare provider.
Timeline: Results are typically available within 10 weeks after the sample is received at the lab.
Patient Instructions
About This Test
Who Should Get This Test
The primary purpose of ATAC sequencing is to assess chromatin accessibility, which reflects the regulatory landscape of the genome. This test helps identify active regulatory elements, transcription factor binding sites, and nucleosome positioning. It is used to understand gene expression regulation, identify disease-associated epigenetic changes, and discover potential biomarkers. In clinical settings, ATAC-seq can aid in diagnosing genetic disorders, characterizing tumors, and guiding targeted therapies.
How to Prepare
- Ensure the sample is collected in a sterile container
- For blood, use EDTA or heparin tube as instructed
- Label the sample with patient ID and date
- Transport the sample to the lab within 24 hours at 2-8°C
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"ATAC-seq provides critical insights into gene regulation, aiding in the diagnosis and research of complex diseases."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed blood sample
- Insufficient DNA quantity or quality
- Sample not labeled correctly
- Sample received after prolonged storage at room temperature
Understanding Your Results
Increased accessibility at promoter regions
Active gene transcription
Decreased accessibility at enhancer regions
Silenced gene expression
Altered nucleosome positioning
Changes in transcription factor binding
Differential accessibility between samples
Potential disease-associated regulatory changes
If you have symptoms suggestive of a genetic or epigenetic disorder, or if you have a family history of such conditions, consult a clinical geneticist or your primary care physician to determine if ATAC sequencing is appropriate.
Limitations
- ⚠Requires high-quality DNA; degraded samples may yield poor results
- ⚠Bioinformatics analysis is complex and requires specialized expertise
- ⚠Interpretation may be limited by reference databases
- ⚠Not a diagnostic test for all genetic conditions; clinical correlation required
Risks & Considerations
- ●Minimal risk of bleeding or bruising at the needle site
- ●Rare risk of infection
- ●No radiation exposure
Interfering Factors
- ●Poor DNA quality or degradation
- ●Insufficient cell number or input DNA
- ●Contamination with genomic DNA or RNA
- ●Batch effects in sequencing
- ●Bioinformatics analysis parameters
Compare With Similar Tests
| Test | ATAC Sequencing and Analysis | ChIP-seq | DNase-seq | MNase-seq | Whole Genome Bisulfite Sequencing (WGBS) |
|---|---|---|---|---|---|
| Comparison | ATAC Sequencing and Analysis |
Frequently Asked Questions
What is ATAC sequencing?
What is the cost of ATAC sequencing in India?
What sample is required for ATAC sequencing?
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Is fasting required before the test?
Can ATAC sequencing diagnose cancer?
Is home sample collection available?
What is the difference between ATAC-seq and RNA-seq?
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Related Tests
Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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