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DNA Labs India

ATAC Sequencing Data Analysis Test

DNA Labs India | ISO 9001:2015 Certified

ATAC Sequencing Data Analysis Test

Short Name: ATAC-seq Analysis

Also known as: ATAC-seq Data Analysis, Assay for Transposase-Accessible Chromatin Sequencing Analysis

ATAC Sequencing Data Analysis Test test available at DNA Labs India for ₹18,000. Uses Next-Generation Sequencing (NGS), Bioinformatics Analysis on Extracted DNA samples. Results in Reports are typically delivered within 4 weeks from the receipt of the sample and data.. Free home collection in 300+ cities across India.

Bioinformatics Analysis🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SHAILAJA RAGHUNATH MURDESHWAR

Dr SHAILAJA RAGHUNATH MURDESHWAR

Consultant Physician · Reg: 8052

Last reviewed: September 7, 2026

Overview

The purpose of ATAC sequencing data analysis is to identify regions of open chromatin that are accessible to transcription factors and other regulatory proteins. This information helps in understanding gene regulatory networks, identifying potential biomarkers, and discovering therapeutic targets. It is widely used in cancer research to study tumor heterogeneity and epigenetic changes, in immunology to map immune cell differentiation, and in neurobiology to explore brain development and disorders. By providing a genome-wide view of chromatin accessibility, ATAC-seq analysis enables researchers to correlate epigenetic states with gene expression and phenotypic outcomes.

Test Code
6408
CPT Code
0000T
ICD Code
Z01.89
Price
₹18,000
Sample Type
Extracted DNA
Result Time
Reports are typically delivered within 4 weeks from the receipt of the sample and data.
Fasting Required
No
Method
Next-Generation Sequencing (NGS), Bioinformatics Analysis
Step 1

Sample Collection

Ensure that the extracted DNA is of high quality (OD260/280 between 1.8-2.0) and free from contaminants. Store DNA at -20°C or -80°C until shipment. Provide all relevant sample information and study details.

Method: Home collection or drop-off

Step 2

Laboratory Analysis

Sample collection is performed by trained professionals. For home collection, the phlebotomist will follow standard protocols to ensure sample integrity.

Step 3

Report Delivery

The sample should be transported to the laboratory within 24 hours if shipped at ambient temperature, or within 7 days if shipped on dry ice. Ensure proper labeling and packaging.

Timeline: Reports are typically delivered within 4 weeks from the receipt of the sample and data.

Patient Instructions

1
Before the Test:No special preparation is required. However, ensure that the DNA sample is of high quality and meets the specified requirements.
2
During the Test:The analysis is performed by bioinformaticians using validated pipelines. No patient involvement is required.
3
After the Test:You will receive a comprehensive report via email or online portal. A geneticist may contact you for discussion if needed.

About This Test

Who Should Get This Test

The purpose of ATAC sequencing data analysis is to identify regions of open chromatin that are accessible to transcription factors and other regulatory proteins. This information helps in understanding gene regulatory networks, identifying potential biomarkers, and discovering therapeutic targets. It is widely used in cancer research to study tumor heterogeneity and epigenetic changes, in immunology to map immune cell differentiation, and in neurobiology to explore brain development and disorders. By providing a genome-wide view of chromatin accessibility, ATAC-seq analysis enables researchers to correlate epigenetic states with gene expression and phenotypic outcomes.

How to Prepare

  • Use sterile DNA LoBind tubes
  • Label the tube with patient ID and date
  • Ship on dry ice for long-distance transport
  • Include a completed requisition form

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"ATAC-seq data analysis provides critical insights into chromatin regulation, aiding in the understanding of gene expression mechanisms and disease pathology."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeExtracted DNA
Sample Volume1-2 µg (as per sequencing requirements)
ContainerDNA LoBind tube
Collection MethodHome collection or drop-off

Sample Stability

DNA at -20°C: 6 months
DNA at -80°C: 2 years
DNA at 4°C: 1 week
DNA at room temperature: 24 hours
Sample Rejection Criteria:
  • Degraded DNA (fragmented)
  • Insufficient quantity (< 500 ng)
  • Contaminated with RNA or proteins
  • Improper labeling
  • Sample not shipped under appropriate conditions

Understanding Your Results

The results of ATAC-seq data analysis are interpreted by identifying regions of open chromatin that may correspond to active regulatory elements. The bioinformatics report includes a list of peaks, their genomic annotations, and differential accessibility between conditions. Enrichment analysis highlights biological pathways that may be affected.
Peaks located in promoter regions suggest active gene transcription
Peaks in enhancer regions indicate potential regulatory activity
Differential accessibility between disease and control samples may reveal disease-associated regulatory changes
Pathway enrichment analysis links accessible regions to biological processes
Integration with gene expression data can confirm regulatory effects
⚠️ When to Consult a Doctor:

If you are a researcher or clinician planning to use ATAC-seq data for diagnostic or therapeutic decisions, it is recommended to consult with a geneticist or bioinformatician to ensure proper interpretation and application.

Limitations

  • ⚠ATAC-seq only identifies open chromatin regions, not direct transcription factor binding
  • ⚠Resolution is limited to nucleosome positioning, not single-base resolution
  • ⚠Requires high-quality input DNA; degraded samples may yield poor results
  • ⚠Bioinformatics analysis is dependent on the quality of sequencing data
  • ⚠Interpretation may require integration with other data types (RNA-seq, ChIP-seq)

Risks & Considerations

  • ●No physical risks as this is a data analysis service
  • ●Potential for inconclusive results if data quality is poor
  • ●Interpretation may require additional validation experiments

Interfering Factors

  • ●Poor quality of input DNA (degraded or contaminated)
  • ●Insufficient sequencing depth
  • ●PCR duplicates
  • ●Batch effects between samples
  • ●Incorrect reference genome version
  • ●Mitochondrial DNA contamination

Compare With Similar Tests

TestATAC Sequencing Data Analysis
ComparisonATAC Sequencing Data Analysis

Frequently Asked Questions

What is ATAC sequencing data analysis?
ATAC sequencing data analysis involves processing raw sequencing data from ATAC-seq experiments to identify open chromatin regions, perform peak calling, and interpret regulatory elements.
What is the cost of ATAC sequencing data analysis at DNA Labs India?
The cost is INR 18000, which includes comprehensive bioinformatics analysis and a detailed report.
What sample type is required for ATAC-seq analysis?
Extracted DNA of high quality is required. The DNA should be intact and free from contaminants.
How long does it take to get the results?
The turnaround time is 4 weeks from the receipt of the sample and data.
Is home sample collection available?
Yes, we offer free home sample collection for online bookings across major cities in India.
What does the analysis include?
The analysis includes alignment to reference genome, peak calling, annotation, differential accessibility, functional pathway analysis, and visualization.
Can ATAC-seq analysis be used for cancer research?
Yes, ATAC-seq is widely used in cancer research to identify regulatory elements involved in tumorigenesis and metastasis.
What is the difference between ATAC-seq and ChIP-seq?
ATAC-seq identifies open chromatin regions, while ChIP-seq identifies binding sites of specific proteins or histone modifications. ATAC-seq requires less input material and is faster.
Do I need to fast before providing a sample?
No, fasting is not required for ATAC-seq data analysis as it is a bioinformatics service.
Will I receive a report with interpretation?
Yes, the report includes detailed results, peak annotations, and pathway analysis, along with an interpretation guide.
Can I use my own sequencing data for analysis?
Yes, you can submit your raw sequencing data (FASTQ files) for analysis. Please contact us for data transfer instructions.
Is this test covered by insurance?
This service is typically not covered by insurance. However, you may check with your insurance provider for possible reimbursement.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

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