Atypical hemolytic uremic syndrome Panel NGS Genetic Test
Short Name: aHUS Panel NGS Test
Also known as: Hemolytic Uremic Syndrome, Atypical, aHUS Genetic Panel, Complement-Mediated aHUS Test
Atypical hemolytic uremic syndrome Panel NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Results are typically available within 3 to 4 weeks after sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
The purpose of this test is to detect genetic mutations in complement-related genes that cause atypical hemolytic uremic syndrome, aiding in definitive diagnosis, family screening, and guiding targeted therapies to prevent kidney failure and other complications.
- Test Code
- 5356
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- Results are typically available within 3 to 4 weeks after sample receipt.
- Fasting Required
- No
- Method
- NGS Technology
Sample Collection
Genetic counseling is recommended to discuss test implications and draw a family pedigree chart.
Method: Venipuncture
Laboratory Analysis
A blood sample is collected via venipuncture by a trained phlebotomist.
Report Delivery
The sample is labeled, stored at ambient room temperature, and sent to the laboratory for NGS analysis.
Timeline: Results are typically available within 3 to 4 weeks after sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to detect genetic mutations in complement-related genes that cause atypical hemolytic uremic syndrome, aiding in definitive diagnosis, family screening, and guiding targeted therapies to prevent kidney failure and other complications.
How to Prepare
- No fasting required prior to sample collection
- Ensure proper identification and labeling of the sample
- Follow standard phlebotomy procedures to avoid hemolysis
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"This genetic test is essential for diagnosing atypical hemolytic uremic syndrome, enabling targeted treatment and management of kidney complications."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood samples
- Insufficient sample volume
- Improperly labeled or contaminated samples
Understanding Your Results
Pathogenic variant detected
Confirms genetic aHUS; consider family screening and targeted therapy.
Variant of uncertain significance (VUS)
Requires clinical correlation and possible additional testing.
No pathogenic variants detected
Genetic cause unlikely; evaluate for other causes of HUS.
Consult a nephrologist or genetic specialist immediately if you experience symptoms like decreased urine output, blood in urine, or swelling, especially with a family history of aHUS.
Limitations
- ⚠May not detect all genetic variants or novel mutations
- ⚠Results require interpretation by a genetic specialist
- ⚠Does not rule out non-genetic causes of HUS
Risks & Considerations
- ●Minimal risk from blood draw, such as slight pain, bruising, or infection at the puncture site.
Interfering Factors
- ●Sample contamination during collection or transport
- ●Technical errors in NGS sequencing
- ●Presence of hemolyzed or degraded DNA samples
Compare With Similar Tests
| Test | Atypical hemolytic uremic syndrome Panel NGS Genetic Test | Kidney Function Test | Complete Blood Count (CBC) | Complement System Panel | ADAMTS13 Activity Test |
|---|---|---|---|---|---|
| Comparison | Atypical hemolytic uremic syndrome Panel NGS Genetic Test | Assesses kidney damage but not genetic cause. | Detects anemia and thrombocytopenia but not specific to aHUS. | Measures complement levels but may not identify genetic mutations. | Differentiates aHUS from TTP but not comprehensive for all genes. |
Frequently Asked Questions
What is the cost of the Atypical Hemolytic Uremic Syndrome Panel NGS Genetic Test?
What are the symptoms of atypical hemolytic uremic syndrome?
How is aHUS diagnosed?
What genes are tested in this panel?
Is fasting required for this test?
How long does it take to get results?
Is home sample collection available?
What is the sample type for this test?
Who should consider this genetic test?
What does a positive result mean?
Are there any risks associated with the test?
How can I book this test?
Related Tests
Amyloid Protein Identification Test
₹300,000CLCNKB Gene Bartter syndrome type 3 NGS Genetic Test
₹20,000SLC12A7 Gene Bartter syndrome NGS Genetic Test
₹20,000SLC12A5 Gene Bartter syndrome NGS Genetic Test
₹20,000SLC12A2 Gene Bartter syndrome NGS Genetic Test
₹20,000KCNJ1 Gene Bartter syndrome type 2 NGS Genetic Test
₹20,000Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
Book Your Test
Enter your details and we'll connect you within 15 minutes.