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AURKC Gene SPGF5 NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

AURKC Gene SPGF5 NGS Genetic Test

Short Name: AURKC SPGF5 Test

Also known as: SPGF5 Syndrome, Aurora Kinase C Related Disorder

AURKC Gene SPGF5 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood, Extracted DNA, or FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

Genetic TestAll Ages🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To identify mutations in the AURKC gene that cause SPGF5 syndrome, enabling accurate diagnosis, genetic counseling, and informed management of reproductive disorders.

Test Code
5551
Price
₹20,000
Sample Type
Blood, Extracted DNA, or FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

Provide clinical history and undergo genetic counseling to draw a pedigree chart of affected family members.

Method: Blood Draw or Saliva Collection

Step 2

Laboratory Analysis

Sample collected via blood draw or saliva, following standard aseptic techniques.

Step 3

Report Delivery

Sample is labeled, stored at ambient temperature, and transported to the laboratory for analysis.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Consult a healthcare provider, provide medical history, and consider genetic counseling.
2
During the Test:Sample collection is quick and minimally invasive, typically taking 10-15 minutes.
3
After the Test:Results are delivered online; follow-up with a specialist is advised for interpretation.

About This Test

Who Should Get This Test

To identify mutations in the AURKC gene that cause SPGF5 syndrome, enabling accurate diagnosis, genetic counseling, and informed management of reproductive disorders.

How to Prepare

  • Use sterile collection tubes
  • Avoid hemolysis in blood samples
  • Store FTA cards at room temperature

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"This test is crucial for diagnosing reproductive disorders linked to AURKC mutations, aiding in family planning and management of SPGF5 syndrome."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood, Extracted DNA, or FTA Card
Collection MethodBlood Draw or Saliva Collection

Sample Stability

Blood: 7 days at 2-8°C
Extracted DNA: 30 days at -20°C
FTA Card: Indefinite at room temperature
Sample Rejection Criteria:
  • Hemolyzed samples
  • Insufficient volume
  • Improperly labeled samples

Understanding Your Results

Results indicate the presence or absence of mutations in the AURKC gene. Positive results suggest a diagnosis of SPGF5 syndrome, while negative results may require further testing.
📊

Positive for pathogenic variant

Confirms diagnosis of SPGF5 syndrome; genetic counseling recommended.

📊

Negative for pathogenic variant

No mutation detected; clinical symptoms may be due to other causes.

📊

Variant of uncertain significance

Further testing or family studies may be needed for clarification.

⚠️ When to Consult a Doctor:

If symptoms of SPGF5 syndrome are present, or for family planning with a history of reproductive disorders.

Limitations

  • ⚠May not detect all genetic variants
  • ⚠Results require clinical correlation
  • ⚠Not suitable for prenatal diagnosis without additional validation

Risks & Considerations

  • ●Minor bruising at blood draw site
  • ●Rare infection risk
  • ●Emotional impact of results

Interfering Factors

  • ●Sample contamination
  • ●Degraded DNA
  • ●Hemolyzed blood samples

Compare With Similar Tests

TestAURKC Gene SPGF5 NGS Genetic TestKAL1 Gene TestCFTR Gene TestFMR1 Gene TestY Chromosome Microdeletion Test
ComparisonAURKC Gene SPGF5 NGS Genetic TestFocuses on Kallmann syndrome, different genetic basis.For cystic fibrosis, unrelated to SPGF5.For Fragile X syndrome, distinct symptoms.For male infertility, different mechanism.

Frequently Asked Questions

What is the AURKC Gene SPGF5 NGS Genetic Test?
It is a genetic test that uses Next-Generation Sequencing to detect mutations in the AURKC gene, which cause SPGF5 syndrome, a rare disorder affecting brain and body development.
What are the symptoms of SPGF5 syndrome?
Symptoms include intellectual disability, seizures, abnormal muscle tone, speech delays, microcephaly, finger and toe abnormalities, and vision or hearing impairments.
How is the test performed?
The test analyzes DNA from blood, extracted DNA, or FTA card samples using NGS technology in a laboratory setting.
What is the cost of the AURKC Gene SPGF5 NGS Genetic Test?
The test costs INR 20,000, which includes sample collection, analysis, and a detailed report.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection across many cities in India for this test.
Who should take this test?
Individuals with symptoms of SPGF5 syndrome or a family history of reproductive disorders should consider this test.
What does a positive result mean?
A positive result indicates a mutation in the AURKC gene, confirming a diagnosis of SPGF5 syndrome, and genetic counseling is recommended.
Are there any risks associated with the test?
Risks are minimal, such as minor bruising from blood draw, but emotional impacts of results should be considered.
How accurate is the test?
The test has high sensitivity (>99%) for detecting mutations, but results should be interpreted by a healthcare professional.
Can the test be used for prenatal diagnosis?
This test is not validated for prenatal diagnosis; consult a specialist for prenatal genetic testing options.
What should I do after receiving the results?
Discuss results with a healthcare provider or genetic counselor to understand implications and plan next steps.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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