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DNA Labs India

AVP Gene Diabetes insipidus, neurohypophyseal NGS Genetic Test

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AVP Gene Diabetes insipidus, neurohypophyseal NGS Genetic Test

Short Name: AVP Gene Diabetes Insipidus NGS Test

Also known as: Vasopressin Deficiency Genetic Test, AVP Mutation Analysis

AVP Gene Diabetes insipidus, neurohypophyseal NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.

NGS Genetic TestAll Ages🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

The purpose of this test is to detect mutations in the AVP gene that cause neurohypophyseal diabetes insipidus, aiding in accurate diagnosis, treatment planning, and genetic counseling.

Test Code
4666
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

No specific preparation required. Provide clinical history and family pedigree.

Method: Venipuncture

Step 2

Laboratory Analysis

Blood sample will be collected via venipuncture or using FTA card.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bruising. Resume normal activities.

Timeline: 3 to 4 weeks

Patient Instructions

1
Before the Test:Provide detailed clinical and family history. Genetic counseling session may be required.
2
During the Test:Sample collection takes a few minutes. No pain beyond a needle prick.
3
After the Test:No downtime. Results available in 3-4 weeks.

About This Test

Who Should Get This Test

The purpose of this test is to detect mutations in the AVP gene that cause neurohypophyseal diabetes insipidus, aiding in accurate diagnosis, treatment planning, and genetic counseling.

How to Prepare

  • Ensure proper identification of the patient
  • Use sterile equipment
  • Label samples correctly
  • Transport samples at ambient temperature

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Genetic testing for AVP gene mutations is essential for diagnosing familial neurohypophyseal diabetes insipidus, enabling targeted treatment and genetic counseling."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume3-5 ml blood or as per requirement
ContainerEDTA tube or FTA card
Collection MethodVenipuncture

Sample Stability

Blood in EDTA tube
FTA card
Sample Rejection Criteria:
  • Hemolyzed samples
  • Insufficient sample volume
  • Incorrect labeling

Understanding Your Results

Results indicate the presence or absence of mutations in the AVP gene. A positive result confirms genetic basis for diabetes insipidus.
📊

Pathogenic variant detected

Confirms diagnosis of AVP gene-related diabetes insipidus. Genetic counseling recommended.

📊

No pathogenic variant detected

AVP gene mutations not found. Consider other diagnostic tests.

📊

Variant of uncertain significance

Further testing and clinical correlation needed.

⚠️ When to Consult a Doctor:

If you experience symptoms of diabetes insipidus or have a family history, consult a geneticist or endocrinologist for evaluation and testing.

Limitations

  • ⚠May not detect all types of mutations
  • ⚠Variants of uncertain significance may be identified
  • ⚠Does not rule out other causes of diabetes insipidus

Risks & Considerations

  • ●Minor bruising at puncture site
  • ●Rare risk of infection
  • ●Psychological impact of genetic results

Interfering Factors

  • ●Poor sample quality
  • ●Contamination during collection
  • ●Insufficient DNA yield

Frequently Asked Questions

What is the AVP Gene Diabetes Insipidus NGS Genetic Test?
This test uses Next-Generation Sequencing to identify mutations in the AVP gene, which causes neurohypophyseal diabetes insipidus, a rare disorder affecting fluid regulation.
What are the symptoms of AVP gene-related diabetes insipidus?
Symptoms include excessive thirst, frequent urination, dehydration, dry mouth, weakness, fatigue, and weight loss. Severe cases can lead to life-threatening complications.
How is the test performed?
A blood sample or DNA extract is collected and analyzed using NGS technology to detect mutations in the AVP gene.
What is the cost of the test in India?
The test costs INR 20,000, with free home sample collection available in many cities across India.
Is home sample collection available?
Yes, free home sample collection is offered for online bookings in numerous cities nationwide.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
What do the results mean?
A positive result indicates a pathogenic mutation in the AVP gene, confirming genetic diabetes insipidus. Negative results suggest no mutations found, but other causes may exist.
Is genetic testing necessary for diagnosis?
Genetic testing provides a definitive diagnosis, especially for familial cases, and guides treatment and genetic counseling.
Can the test detect all mutations?
While NGS is comprehensive, it may not detect all mutation types, and variants of uncertain significance may be identified.
What are the risks of the test?
Risks are minimal, including minor bruising at the puncture site and rare infection. Psychological impact of results should be considered.
How should I prepare for the test?
No special preparation is needed. Provide a detailed clinical and family history, and attend a genetic counseling session if recommended.
Is the test covered by insurance?
Coverage varies by insurance plan. It is advisable to check with your provider and discuss with a genetic counselor.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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