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AVPR2 Gene Nephrogenic syndrome of inapproriate antidiuresis NGS Genetic Test

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AVPR2 Gene Nephrogenic syndrome of inapproriate antidiuresis NGS Genetic Test

Also known as: NSIAD, AVPR2-related Nephrogenic Syndrome of Inappropriate Antidiuresis

AVPR2 Gene Nephrogenic syndrome of inapproriate antidiuresis NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.

NGS Genetic TestAll Ages🏠 Home Collection

🩺 Medically Reviewed By

Overview

To diagnose mutations in the AVPR2 gene associated with Nephrogenic Syndrome of Inappropriate Antidiuresis for early intervention and management.

Test Code
5457
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

Provide clinical history and undergo genetic counseling to draw a pedigree chart of family members.

Method: Venipuncture

Step 2

Laboratory Analysis

Blood sample collection via venipuncture or use of FTA card for one drop of blood.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bruising.

Timeline: 3 to 4 weeks

Patient Instructions

1
Before the Test:Genetic counseling recommended to discuss test implications and family history.
2
During the Test:Sample collection and analysis using NGS technology.
3
After the Test:Report generation and consultation with a healthcare provider for interpretation.

About This Test

Who Should Get This Test

To diagnose mutations in the AVPR2 gene associated with Nephrogenic Syndrome of Inappropriate Antidiuresis for early intervention and management.

How to Prepare

  • Clinical history of patient
  • Genetic counseling session to draw pedigree chart of family members affected with AVPR2 gene mutations

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Early genetic testing for AVPR2 mutations can guide treatment and prevent complications in NSIAD patients, especially in families with a history of the disorder."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Collection MethodVenipuncture

Understanding Your Results

Results indicate the presence or absence of mutations in the AVPR2 gene, which can confirm or rule out NSIAD.
Positive: Pathogenic variant detected, indicating risk for NSIAD and guiding treatment.
Negative: No pathogenic variants detected, reducing likelihood of genetic NSIAD.
Variant of uncertain significance: Further testing or clinical correlation may be needed.
⚠️ When to Consult a Doctor:

If symptoms of excessive thirst, frequent urination, or dehydration are present, or if there is a family history of NSIAD, consult a healthcare provider for evaluation and possible testing.

Risks & Considerations

  • Minor bruising at the puncture site
  • Rare risk of infection

Frequently Asked Questions

What is AVPR2 Gene Nephrogenic Syndrome of Inappropriate Antidiuresis (NSIAD)?
NSIAD is a rare genetic disorder caused by mutations in the AVPR2 gene, leading to excessive water retention and symptoms like constant thirst and frequent urination.
What are the symptoms of NSIAD?
Symptoms include excessive thirst, frequent urination, dehydration, seizures in children, developmental delays, and failure to thrive.
How is NSIAD diagnosed?
Diagnosis involves genetic testing, such as the NGS Genetic Test, to identify mutations in the AVPR2 gene.
What is the NGS Genetic Test for AVPR2 gene?
It is a Next-Generation Sequencing test that detects mutations in the AVPR2 gene to diagnose NSIAD.
What is the cost of the AVPR2 Gene NSIAD NGS Test at DNA Labs India?
The test costs INR 20,000 at DNA Labs India.
What sample is required for the test?
The test requires blood, extracted DNA, or one drop of blood on an FTA card.
How long does it take to get the test results?
Reports are typically available in 3 to 4 weeks.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for online bookings across India.
What are the risks of the test?
Risks are minimal and may include minor bruising at the puncture site or rare infection.
Can NSIAD be treated after diagnosis?
While there is no cure, early diagnosis allows for management of symptoms and prevention of complications through medical intervention.
Who should consider getting this test?
Individuals with symptoms of NSIAD, such as excessive thirst or dehydration, or those with a family history of the disorder should consider testing.
How accurate is the NGS Genetic Test for AVPR2 mutations?
The test is highly accurate for detecting pathogenic mutations in the AVPR2 gene, but results should be interpreted by a healthcare professional.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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