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DNA Labs India

Bone Marrow Trephine Biopsy Panel Test

DNA Labs India | ISO 9001:2015 Certified

Bone Marrow Trephine Biopsy Panel Test

Also known as: Bone Marrow Biopsy, Trephine Biopsy Panel

Bone Marrow Trephine Biopsy Panel Test test available at DNA Labs India for ₹1,439. Uses Processing, Staining, Microscopy on Bone marrow tissue samples. Results in Report available within 5 working days after sample collection.. Free home collection in 300+ cities across India.

Biopsy Panel🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SHAILAJA RAGHUNATH MURDESHWAR

Dr SHAILAJA RAGHUNATH MURDESHWAR

Consultant Physician · Reg: 8052

Last reviewed: September 7, 2026

Overview

The purpose of the Bone Marrow Trephine Biopsy Panel Test is to perform histopathological examination, reticulin staining to assess fibrosis, and iron staining to evaluate iron stores in the bone marrow, aiding in the diagnosis of hematopoietic disorders.

Test Code
217
Price
₹1,439
Sample Type
Bone marrow tissue
Result Time
Report available within 5 working days after sample collection.
Fasting Required
No
Method
Processing, Staining, Microscopy
Step 1

Sample Collection

Duly filled Bone Marrow Examination Requisition Form (Form 14) is mandatory.

Method: Bone marrow biopsy procedure

Step 2

Laboratory Analysis

The biopsy is performed under local anesthesia from the posterior iliac crest. A biopsy needle is inserted to extract a core sample.

Step 3

Report Delivery

Apply pressure to the biopsy site. Monitor for bleeding or infection. The sample is sent to the lab in 10% formal-saline.

Timeline: Report available within 5 working days after sample collection.

Patient Instructions

1
Before the Test:Ensure the requisition form is filled. Inform your doctor about any medications, allergies, or medical conditions.
2
During the Test:The procedure takes about 15-30 minutes. Local anesthesia is administered, and you may feel pressure or mild discomfort during biopsy.
3
After the Test:Rest and apply pressure to the site. Avoid strenuous activity for 24-48 hours. Watch for signs of infection or excessive bleeding.

About This Test

Who Should Get This Test

The purpose of the Bone Marrow Trephine Biopsy Panel Test is to perform histopathological examination, reticulin staining to assess fibrosis, and iron staining to evaluate iron stores in the bone marrow, aiding in the diagnosis of hematopoietic disorders.

How to Prepare

  • Submit specimen in 10% Formal-saline
  • Ship at room temperature
  • Duly filled Bone Marrow Examination Requisition Form (Form 14) is mandatory

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"This test is essential for detailed assessment of bone marrow architecture, aiding in the diagnosis and monitoring of hematologic disorders such as anemia, leukemia, and myelofibrosis."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBone marrow tissue
Sample VolumeNot specified
Container10% Formal-saline container
Collection MethodBone marrow biopsy procedure

Sample Stability

Stable at room temperature for 24 hours in formal-saline
Sample Rejection Criteria:
  • Incomplete requisition form
  • Improper sample container
  • Damaged or insufficient specimen

Understanding Your Results

Results are interpreted by a pathologist based on histopathological findings, staining patterns, and clinical context.
Increased cellularity may indicate hyperplasia or malignancy
Reticulin fibrosis suggests conditions like myelofibrosis
Low iron stores indicate iron deficiency anemia
Presence of abnormal cells may indicate leukemia or lymphoma
⚠️ When to Consult a Doctor:

If you experience symptoms like persistent fatigue, unexplained weight loss, or abnormal blood counts, consult a hematologist or healthcare provider for evaluation.

Limitations

  • ⚠Sample quality dependent on procedure
  • ⚠Interpretation requires specialized expertise
  • ⚠May not detect all hematologic abnormalities

Risks & Considerations

  • ●Bleeding at biopsy site
  • ●Infection
  • ●Pain or discomfort
  • ●Rarely, bone fracture or nerve injury

Interfering Factors

  • ●Inadequate sample quality
  • ●Improper fixation or staining
  • ●Contamination during processing

Compare With Similar Tests

TestBone Marrow Trephine Biopsy Panel Test
ComparisonBone Marrow Trephine Biopsy Panel Test

Frequently Asked Questions

What is the Bone Marrow Trephine Biopsy Panel Test?
It is a diagnostic procedure that involves removing a small core of bone marrow tissue for histopathological analysis, including reticulin and iron stains, to diagnose blood and bone marrow disorders.
Why is this test recommended?
It is recommended for evaluating symptoms like fatigue, weight loss, or abnormal blood counts, and for diagnosing conditions such as anemia, leukemia, and myelofibrosis.
How is the biopsy sample collected?
A biopsy needle is inserted into the posterior iliac crest bone under local anesthesia to extract a cylindrical tissue sample.
Is the test painful?
Local anesthesia minimizes pain, but you may feel pressure or mild discomfort during the procedure.
What are the risks associated with the biopsy?
Risks include bleeding, infection, pain, and rarely, bone fracture or nerve injury.
How long does the procedure take?
The biopsy itself takes about 15-30 minutes, excluding preparation and recovery time.
Do I need to fast before the test?
No fasting is required, but a duly filled Bone Marrow Examination Requisition Form is mandatory.
What should I bring to the test appointment?
Bring the completed requisition form, valid ID, and any relevant medical records or doctor's referral.
How will I receive my test results?
Results are available online via portal, email, or WhatsApp within 5 working days.
What do abnormal results indicate?
Abnormal results may suggest conditions like bone marrow fibrosis, iron deficiency, hematologic malignancies, or other disorders requiring further evaluation.
Can this test diagnose all blood cancers?
It provides detailed bone marrow analysis, which is crucial for diagnosing many hematologic cancers, but may be used alongside other tests for comprehensive diagnosis.
What is the cost and is home collection available?
The test costs INR 1439.1, and free home sample collection is available across many cities in India for online bookings.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.
For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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