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C4BPA Gene Pregnancy loss, recurrent, C4BPA related NGS Genetic Test

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C4BPA Gene Pregnancy loss, recurrent, C4BPA related NGS Genetic Test

Short Name: C4BPA Gene Test

Also known as: C4BPA Genetic Test for Miscarriage, C4BPA Mutation Analysis

C4BPA Gene Pregnancy loss, recurrent, C4BPA related NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

GynecologyFemaleReproductive Age🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To identify mutations in the C4BPA gene associated with recurrent pregnancy loss, aiding in diagnosis and personalized treatment planning.

Test Code
5546
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

No specific preparation required. Provide clinical history and undergo genetic counseling.

Method: Blood Draw

Step 2

Laboratory Analysis

A blood sample is drawn from a vein in the arm or a drop of blood is collected on an FTA card.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bleeding. Resume normal activities.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Understand the test purpose, provide informed consent, and share family medical history.
2
During the Test:The test involves a simple blood draw or FTA card collection, taking about 10-15 minutes.
3
After the Test:Wait for results in 3-4 weeks. Genetic counseling will be provided to discuss findings.

About This Test

Who Should Get This Test

To identify mutations in the C4BPA gene associated with recurrent pregnancy loss, aiding in diagnosis and personalized treatment planning.

How to Prepare

  • Fast for 8-12 hours if specified, though not required for this test
  • Bring identification and doctor's prescription
  • Inform about any medications or conditions

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Genetic testing for C4BPA can help identify causes of recurrent pregnancy loss and guide personalized treatment plans for couples."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Collection MethodBlood Draw

Sample Stability

Blood samples stable for 48 hours at room temperature
Extracted DNA stable for longer periods if stored properly
Sample Rejection Criteria:
  • Hemolyzed or contaminated samples
  • Insufficient sample volume
  • Incorrect labeling

Understanding Your Results

Results indicate the presence or absence of mutations in the C4BPA gene. Positive results may suggest an increased risk for recurrent pregnancy loss.
Normal: No pathogenic variants detected, indicating low genetic risk
Abnormal: Pathogenic variants found, associated with higher pregnancy loss risk
Consult a genetic counselor for detailed interpretation and next steps
⚠️ When to Consult a Doctor:

If results show mutations or if you have a history of recurrent pregnancy loss, consult a gynecologist or genetic specialist for management options.

Limitations

  • ⚠May not detect all genetic variants
  • ⚠Results require clinical correlation
  • ⚠Does not rule out other causes of pregnancy loss

Risks & Considerations

  • ●Minimal risk from blood draw, such as bruising or infection
  • ●Psychological impact of results
  • ●False positives or negatives possible

Interfering Factors

  • ●Sample contamination
  • ●Degraded DNA
  • ●Incorrect sample handling

Compare With Similar Tests

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ComparisonC4BPA Gene Pregnancy loss, recurrent, C4BPA related NGS Genetic Test

Frequently Asked Questions

What is the C4BPA gene?
The C4BPA gene produces a protein that regulates the immune system and prevents inflammation. Mutations can increase pregnancy loss risk.
How is the C4BPA gene test performed?
It uses Next-Generation Sequencing (NGS) to analyze a blood sample for mutations in the C4BPA gene.
What is the cost of the C4BPA gene test in India?
The test costs INR 20000 at DNA Labs India, with home collection available.
Who should consider this test?
Women with recurrent pregnancy loss, family history of miscarriage, or related symptoms like preeclampsia.
Is the test painful?
No, it involves a standard blood draw, which may cause minor discomfort.
How long does it take to get results?
Results are available in 3 to 4 weeks after sample collection.
What do positive results mean?
Positive results indicate mutations in the C4BPA gene, which may increase the risk of recurrent pregnancy loss.
Can this test prevent pregnancy loss?
The test identifies genetic risks, allowing for personalized treatment to reduce future pregnancy loss chances.
Is home sample collection available?
Yes, DNA Labs India offers free home collection across many cities in India.
What should I do before the test?
Provide clinical history, undergo genetic counseling, and follow any specific instructions from your doctor.
Are there any risks associated with the test?
Risks are minimal, such as bruising from blood draw, but psychological impact of results should be considered.
How accurate is the C4BPA gene test?
The test uses advanced NGS technology for high accuracy, but results should be interpreted by a genetic counselor.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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