C4orf26 Gene Amelogenesis imperfecta type 2A4 NGS Genetic Test
Short Name: C4orf26 AI Type 2A4 NGS Test
Also known as: Amelogenesis Imperfecta Type 2A4 Genetic Test, C4orf26 Mutation Analysis, Enamel Defect Genetic Test
C4orf26 Gene Amelogenesis imperfecta type 2A4 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of the C4orf26 Gene Amelogenesis Imperfecta Type 2A4 NGS Genetic Test is to detect mutations in the C4orf26 gene that cause Amelogenesis Imperfecta Type 2A4. This helps in confirming the diagnosis, understanding the genetic basis of the disorder, guiding treatment options, and providing information for genetic counseling and family planning.
- Test Code
- 4838
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No specific preparation required. Ensure genetic counseling session is scheduled to discuss family history and draw a pedigree chart.
Method: Venipuncture or finger-prick
Laboratory Analysis
A blood sample will be drawn from a vein in the arm or a finger-prick for FTA card collection. The process takes about 10-15 minutes.
Report Delivery
Apply pressure to the puncture site to prevent bleeding. Resume normal activities immediately. Store samples as instructed for stability.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the C4orf26 Gene Amelogenesis Imperfecta Type 2A4 NGS Genetic Test is to detect mutations in the C4orf26 gene that cause Amelogenesis Imperfecta Type 2A4. This helps in confirming the diagnosis, understanding the genetic basis of the disorder, guiding treatment options, and providing information for genetic counseling and family planning.
How to Prepare
- Avoid eating or drinking for 30 minutes before blood draw if specified
- Ensure proper patient identification
- Use sterile collection equipment
- Label samples correctly with patient details
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Genetic testing for Amelogenesis Imperfecta Type 2A4 can aid in early diagnosis, guide dental treatment, and inform family planning decisions."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted samples
- Insufficient sample volume
- Incorrect labeling or documentation
Understanding Your Results
Pathogenic variant detected
Confirms diagnosis of Amelogenesis Imperfecta Type 2A4. Genetic counseling and dental management recommended.
Likely pathogenic variant detected
Suggests high risk for AI Type 2A4. Further clinical evaluation and family testing advised.
No pathogenic variant detected
C4orf26 gene mutations not found. Consider other genetic or environmental causes of enamel defects.
Variant of uncertain significance
Genetic variant identified but clinical significance unknown. Repeat testing or family studies may be needed.
Consult a doctor or genetic counselor if you experience symptoms of Amelogenesis Imperfecta, have a family history of the condition, or receive a positive genetic test result for guidance on treatment and family planning.
Limitations
- ⚠Test only screens for mutations in the C4orf26 gene
- ⚠May not detect all genetic causes of Amelogenesis Imperfecta
- ⚠Results require interpretation by a genetic specialist
Risks & Considerations
- ●Minimal risk from blood draw, such as bruising or infection
- ●Emotional impact from genetic results; genetic counseling recommended
Interfering Factors
- ●Sample contamination during collection
- ●Degraded DNA due to improper storage
- ●Hemolyzed blood samples
Compare With Similar Tests
| Test | C4orf26 Gene Amelogenesis imperfecta type 2A4 NGS Genetic Test | Whole Exome Sequencing for AI | FAM83H Gene Test for AI | ENAM Gene Test for AI | Dental X-ray |
|---|---|---|---|---|---|
| Comparison | C4orf26 Gene Amelogenesis imperfecta type 2A4 NGS Genetic Test |
Frequently Asked Questions
What is Amelogenesis Imperfecta Type 2A4?
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₹20,000Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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