CALM2 Gene Long QT syndrome type 15 NGS Genetic Test
Short Name: CALM2 LQTS Type 15 NGS Test
Also known as: CALM2 Gene Test, LQTS Type 15 Genetic Test, Long QT Syndrome Genetic Test
CALM2 Gene Long QT syndrome type 15 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
To diagnose Long QT Syndrome Type 15 by identifying mutations in the CALM2 gene using NGS technology, aiding in clinical management and genetic counseling.
- Test Code
- 2544
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
Genetic counseling recommended to discuss implications, and provide detailed clinical and family history.
Method: Venipuncture or FTA card collection
Laboratory Analysis
Standard blood draw via venipuncture or application of one drop of blood on FTA card, performed by trained phlebotomist.
Report Delivery
Sample is labeled, stored appropriately, and transported to the laboratory for DNA extraction and NGS analysis.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
To diagnose Long QT Syndrome Type 15 by identifying mutations in the CALM2 gene using NGS technology, aiding in clinical management and genetic counseling.
How to Prepare
- No fasting required
- Provide accurate clinical history and pedigree chart
- Ensure proper sample labeling
- Avoid hemolysis during blood collection
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"This test is essential for identifying genetic predispositions to Long QT Syndrome, enabling early intervention and family screening."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood sample
- Insufficient sample volume
- Incorrect sample type or container
- Missing patient identification or consent
Understanding Your Results
Positive for pathogenic variant
Confirms diagnosis of LQTS Type 15; risk of cardiac arrhythmias; recommend cardiology follow-up and family screening.
Negative for pathogenic variant
No CALM2 mutations detected; does not exclude other LQTS causes; clinical evaluation and additional testing may be needed.
Variant of uncertain significance (VUS)
Genetic change with unclear clinical impact; require further studies and genetic counseling.
Consult a cardiologist or genetic specialist if you experience symptoms like fainting, palpitations, or have a family history of LQTS, regardless of test results.
Limitations
- ⚠May not detect all genetic variants, including large deletions or duplications
- ⚠Results require correlation with clinical findings and family history
- ⚠Genetic counseling is essential for interpretation
- ⚠Does not rule out other forms of LQTS or cardiac disorders
Risks & Considerations
- ●Minimal risk from blood draw, such as bruising or infection
- ●Psychological impact of genetic results, including anxiety
- ●Potential for uncertain results requiring further testing
Interfering Factors
- ●Sample contamination or degradation
- ●Inadequate DNA quality or quantity
- ●Technical errors in sequencing
- ●Presence of variants of uncertain significance (VUS)
Compare With Similar Tests
| Test | CALM2 Gene Long QT syndrome type 15 NGS Genetic Test | KCNQ1 Gene LQTS Type 1 Test | KCNH2 Gene LQTS Type 2 Test | SCN5A Gene LQTS Type 3 Test | Comprehensive LQTS Panel |
|---|---|---|---|---|---|
| Comparison | CALM2 Gene Long QT syndrome type 15 NGS Genetic Test |
Frequently Asked Questions
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