Cancer Breast Comprehensive Panel Test
Short Name: Breast Cancer Comprehensive Panel
Also known as: Breast Cancer Genetic Panel, BRCA Panel Test, Hereditary Breast Cancer Panel
Cancer Breast Comprehensive Panel Test test available at DNA Labs India for ₹10,000. Uses Immunohistochemistry, FISH, Next-Generation Sequencing (NGS) on Submit tumor tissue in 10% Formalin OR Formalin fixed paraffin embedded tissue block. samples. Results in Reports are typically available within 10 working days after sample receipt at the laboratory.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
The purpose of the Cancer Breast Comprehensive Panel Test is to identify genetic mutations linked to breast cancer for early detection, risk assessment, and personalized treatment planning. It helps in diagnosing breast cancer early, guiding therapeutic decisions, and informing preventive measures for high-risk individuals.
- Test Code
- 254
- Price
- ₹10,000
- Sample Type
- Submit tumor tissue in 10% Formalin OR Formalin fixed paraffin embedded tissue block.
- Result Time
- Reports are typically available within 10 working days after sample receipt at the laboratory.
- Fasting Required
- No
- Method
- Immunohistochemistry, FISH, Next-Generation Sequencing (NGS)
Sample Collection
Ensure proper fixation of tumor tissue as per guidelines. Provide a copy of histopathology report and clinical history. No special preparation required for tissue sample.
Method: Biopsy or surgical sample collection
Laboratory Analysis
Sample collection involves biopsy or surgical procedure to obtain tumor tissue, which is then placed in 10% Formalin or as FFPE block. For home collection, a trained phlebotomist or technician may assist if blood sample is used, but the test specifies tissue sample.
Report Delivery
Store sample at room temperature and ship to the lab promptly. Keep documentation like histopathology report ready for submission with the sample.
Timeline: Reports are typically available within 10 working days after sample receipt at the laboratory.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the Cancer Breast Comprehensive Panel Test is to identify genetic mutations linked to breast cancer for early detection, risk assessment, and personalized treatment planning. It helps in diagnosing breast cancer early, guiding therapeutic decisions, and informing preventive measures for high-risk individuals.
How to Prepare
- Submit tumor tissue in 10% Formalin or as Formalin fixed paraffin embedded tissue block
- Ship sample at room temperature
- Include a copy of the histopathology report, clinical history, and indicate biopsy site
- For home collection, schedule appointment and ensure sample integrity
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"This genetic panel is crucial for assessing breast cancer risk, guiding early detection strategies, and informing personalized treatment plans for patients."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Sample not fixed in 10% Formalin or improper FFPE preparation
- Missing histopathology report or clinical history
- Insufficient tissue quantity or poor quality
- Sample contaminated or degraded
Understanding Your Results
Negative
No pathogenic mutations detected in the tested genes; risk may be similar to general population, but clinical correlation is advised.
Positive
Pathogenic variant detected in one or more genes, indicating increased breast cancer risk; genetic counseling and personalized management recommended.
Variant of Uncertain Significance (VUS)
Genetic variant found but clinical significance unknown; may require periodic reevaluation or additional testing.
HER-2 Positive
Overexpression of HER-2 protein, which may influence treatment options like targeted therapies.
ER/PR Positive
Hormone receptor-positive status, suggesting potential response to hormone therapy.
Consult a doctor immediately if you experience symptoms like breast lumps, changes in breast appearance, nipple discharge, or have a family history of breast cancer. After testing, consult for result interpretation and management plans.
Limitations
- ⚠May not detect all genetic mutations or variants of uncertain significance
- ⚠Results require interpretation by qualified geneticists or oncologists
- ⚠Does not replace diagnostic tests like mammography or biopsy for definitive diagnosis
- ⚠Limited to genes included in the panel; other cancer-related genes may not be covered
Risks & Considerations
- ●Minimal risk for blood sample collection (e.g., bruising)
- ●Higher risk for biopsy procedures (e.g., infection, bleeding)
- ●Psychological impact of genetic results; counseling recommended
Interfering Factors
- ●Poor sample quality or insufficient tissue
- ●Contamination during sample collection or processing
- ●Use of certain fixatives that may degrade DNA
- ●Technical errors in sequencing or analysis
Compare With Similar Tests
| Test | Cancer Breast Comprehensive Panel Test | Mammography | Breast Ultrasound | MRI Scan | Biopsy | BRCA Single Gene Test |
|---|---|---|---|---|---|---|
| Comparison | Cancer Breast Comprehensive Panel Test | Imaging test for breast abnormalities; non-invasive but may not detect genetic mutations. | Uses sound waves to examine breast tissue; useful for dense breasts but lacks genetic insights. | Detailed imaging for high-risk individuals; complementary to genetic testing but not a substitute. | Tissue sampling for histological analysis; confirms cancer but does not provide comprehensive genetic profile. | Tests specific BRCA genes only; the comprehensive panel covers multiple genes for broader assessment. |
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