CAST Gene Peeling skin with leukonychia, acral punctate keratoses, cheilitis, and knuckle pads NGS Genetic Test
Also known as: PPK-SC
CAST Gene Peeling skin with leukonychia, acral punctate keratoses, cheilitis, and knuckle pads NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
To diagnose PPK-SC by identifying pathogenic mutations in the CAST gene using NGS technology, enabling accurate genetic counseling and management.
- Test Code
- 5108
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- NGS Technology
Sample Collection
A certified phlebotomist visits your home or you visit our nearest center. The process takes under 5 minutes.
Laboratory Analysis
Your sample is analyzed using NGS Technology in our laboratory.
Report Delivery
A certified pathologist reviews and signs your report. You receive it as a secure PDF via email and WhatsApp.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
To diagnose PPK-SC by identifying pathogenic mutations in the CAST gene using NGS technology, enabling accurate genetic counseling and management.
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Understanding Your Results
Positive for pathogenic variant
Confirms diagnosis of PPK-SC; genetic counseling recommended.
Negative for pathogenic variant
No mutation detected; consider other diagnoses or repeat testing if clinically indicated.
Variant of uncertain significance
Further testing or family studies may be needed for clarification.
Consult a dermatologist or geneticist if you experience symptoms of PPK-SC or have a family history, to discuss test results and management options.
Risks & Considerations
- ●Psychological impact of genetic results
- ●Potential for variants of uncertain significance
- ●Privacy concerns with genetic data storage
Frequently Asked Questions
What is the CAST Gene NGS Genetic Test?
What is PPK-SC?
What are the symptoms of PPK-SC?
How is the test performed?
What sample is required?
How long does it take to get results?
What is the cost of the test?
Is home collection available?
What does a positive result mean?
Can this test be used for family planning?
Are there any risks associated with the test?
How can I book the test?
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₹20,000Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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