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CDKN2B Gene Multiple endocrine neoplasia type 1, CDKN2B related NGS Genetic Test

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CDKN2B Gene Multiple endocrine neoplasia type 1, CDKN2B related NGS Genetic Test

Short Name: CDKN2B Genetic Test

Also known as: CDKN2B Gene Analysis, CDKN2B Mutation Test, MEN1 Genetic Test

CDKN2B Gene Multiple endocrine neoplasia type 1, CDKN2B related NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

The purpose of the CDKN2B Gene NGS Genetic Test is to detect mutations or variants in the CDKN2B gene that may be associated with genetic conditions, including those affecting cell cycle regulation. While it is not a primary diagnostic test for MEN1, it can be part of comprehensive genetic evaluation for individuals with a family history or symptoms suggestive of endocrine tumors. This test helps in identifying genetic predispositions, guiding clinical management, and informing family planning decisions.

Test Code
2909
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

No specific preparation is required. Ensure genetic counseling is completed and clinical history is provided.

Step 2

Laboratory Analysis

A blood sample will be collected via venipuncture or a drop on FTA card. The process is quick and minimally invasive.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bruising. Resume normal activities immediately.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Complete genetic counseling and provide detailed clinical and family history. No fasting is required.
2
During the Test:A blood sample is drawn from a vein in the arm. The procedure takes about 10-15 minutes.
3
After the Test:You can resume normal activities. Results will be available in 3-4 weeks via online portal, email, or WhatsApp.

About This Test

Who Should Get This Test

The purpose of the CDKN2B Gene NGS Genetic Test is to detect mutations or variants in the CDKN2B gene that may be associated with genetic conditions, including those affecting cell cycle regulation. While it is not a primary diagnostic test for MEN1, it can be part of comprehensive genetic evaluation for individuals with a family history or symptoms suggestive of endocrine tumors. This test helps in identifying genetic predispositions, guiding clinical management, and informing family planning decisions.

How to Prepare

  • Use sterile equipment for blood collection
  • Label samples correctly with patient details
  • Store samples at ambient room temperature as specified
  • Transport to the laboratory within the recommended timeframe

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Genetic testing for conditions like MEN1 should be guided by healthcare professionals. While CDKN2B gene analysis is available, MEN1 is primarily associated with MEN1 gene mutations. Consult a genetic counselor for personalized advice."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card

Sample Stability

Blood samples: Stable at room temperature for up to 48 hours
Extracted DNA: Stable at -20°C for long-term storage
FTA Card samples: Stable at room temperature for extended periods
Sample Rejection Criteria:
  • Insufficient sample volume
  • Hemolyzed or contaminated samples
  • Incorrect labeling or missing patient information
  • Samples not stored or transported as per guidelines

Understanding Your Results

Results from the CDKN2B Gene NGS Genetic Test indicate the presence or absence of mutations in the CDKN2B gene. Positive findings may suggest a genetic predisposition, but clinical significance must be evaluated by a healthcare provider.
Negative Result: No pathogenic variants detected in the CDKN2B gene. Does not rule out other genetic causes.
Positive Result: Pathogenic or likely pathogenic variants identified. Requires genetic counseling and further clinical evaluation.
Variant of Uncertain Significance (VUS): Genetic change with unknown clinical impact. May need additional testing or family studies.
Inconclusive Result: Technical issues or insufficient data. Repeat testing or alternative methods may be recommended.
⚠️ When to Consult a Doctor:

Consult a doctor if you have a family history of MEN1, experience symptoms like hypercalcemia or tumors, or receive a positive or uncertain genetic test result. Genetic counseling is advised for all individuals undergoing testing.

Limitations

  • ⚠May not detect all types of genetic variants, such as large deletions or duplications
  • ⚠Results require interpretation by a genetic specialist
  • ⚠Not a standalone diagnostic test for MEN1; clinical correlation is necessary
  • ⚠Turnaround time of 3-4 weeks may delay clinical decisions

Risks & Considerations

  • ●Minor pain or bruising at the blood draw site
  • ●Very low risk of infection or fainting
  • ●Psychological impact of genetic results; counseling is recommended

Interfering Factors

  • ●Sample contamination during collection or transport
  • ●Degraded DNA due to improper storage
  • ●Presence of inhibitors in the sample affecting sequencing
  • ●Technical errors in NGS library preparation

Compare With Similar Tests

TestCDKN2B Gene Multiple endocrine neoplasia type 1, CDKN2B related NGS Genetic TestMEN1 Gene SequencingEndocrine Neoplasia Gene PanelCDKN2A Gene Test
ComparisonCDKN2B Gene Multiple endocrine neoplasia type 1, CDKN2B related NGS Genetic Test

Frequently Asked Questions

What is the CDKN2B Gene NGS Genetic Test?
It is a next-generation sequencing test that analyzes the CDKN2B gene for mutations, which may be associated with genetic conditions affecting cell cycle regulation.
Is this test used to diagnose Multiple Endocrine Neoplasia Type 1 (MEN1)?
While the test analyzes CDKN2B, MEN1 is primarily caused by mutations in the MEN1 gene. This test may be part of a broader genetic evaluation but is not the standard diagnostic test for MEN1.
What is the cost of the CDKN2B Gene Test in India?
The cost is INR 20000, which includes sample collection, NGS analysis, and report delivery.
How is the sample collected for this test?
A blood sample is collected via venipuncture, or a drop of blood can be placed on an FTA card. Home collection is available across India.
Do I need to fast before the test?
No, fasting is not required for this genetic test.
How long does it take to get the results?
Results are typically available within 3 to 4 weeks after sample collection.
What do the results mean?
Results indicate the presence or absence of mutations in the CDKN2B gene. A negative result means no pathogenic variants were detected, while a positive result requires genetic counseling for interpretation.
Is genetic counseling necessary before taking this test?
Yes, genetic counseling is recommended to understand the implications of testing, especially for hereditary conditions like MEN1.
Can this test be done at home?
Yes, DNA Labs India offers free home sample collection for online bookings in many cities across India.
What are the risks of this test?
The risks are minimal, similar to a standard blood draw, including minor pain or bruising. Psychological risks related to genetic results can be mitigated with counseling.
Is the test covered by insurance?
Coverage depends on your insurance policy. It is not typically covered under government schemes like PMJAY or CGHS; check with your insurer for details.
How accurate is the CDKN2B Gene Test?
The test uses advanced NGS technology with high accuracy for detecting variants in the CDKN2B gene. However, clinical correlation is essential for diagnosis.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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