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DNA Labs India

CDON Gene Holoprosencephaly type 11 NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

CDON Gene Holoprosencephaly type 11 NGS Genetic Test

Also known as: HPE11, CDON-related Holoprosencephaly

CDON Gene Holoprosencephaly type 11 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic TestPediatric🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

The purpose of the CDON Gene Holoprosencephaly Type 11 NGS Genetic Test is to identify mutations in the CDON gene that cause Holoprosencephaly type 11. This test aids in the diagnosis of HPE11, helps determine the genetic basis of the condition, and informs management strategies and family planning.

Test Code
5780
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

Provide clinical history and undergo genetic counseling.

Step 2

Laboratory Analysis

Blood sample will be collected via venipuncture.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bruising.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Genetic counseling and clinical evaluation recommended.
2
During the Test:Sample collection procedure.
3
After the Test:Wait for results and follow up with healthcare provider.

About This Test

Who Should Get This Test

The purpose of the CDON Gene Holoprosencephaly Type 11 NGS Genetic Test is to identify mutations in the CDON gene that cause Holoprosencephaly type 11. This test aids in the diagnosis of HPE11, helps determine the genetic basis of the condition, and informs management strategies and family planning.

How to Prepare

  • Bring identification and prescription
  • Inform about any medications
  • Follow standard blood draw procedures

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"Genetic testing for CDON mutations is crucial for early diagnosis and management of Holoprosencephaly type 11, especially in families with a history of the condition."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card

Sample Stability

Blood: Stable for 24 hours at room temperature
Extracted DNA: Stable for longer periods
Sample Rejection Criteria:
  • Hemolyzed or lipemic samples
  • Insufficient sample volume
  • Improperly labeled samples

Understanding Your Results

Results of the CDON Gene test indicate the presence or absence of mutations in the CDON gene.
Positive: Pathogenic variant detected, confirming HPE11
Negative: No pathogenic variants detected, but clinical correlation needed
Variant of uncertain significance: Further testing may be required
⚠️ When to Consult a Doctor:

If test results are positive or if there are clinical symptoms suggestive of HPE11, consult a geneticist or pediatrician for management.

Limitations

  • ⚠May not detect all types of mutations
  • ⚠Requires genetic counseling for interpretation
  • ⚠Results may have implications for family members

Risks & Considerations

  • ●Minimal risk from blood draw, such as bruising or infection

Interfering Factors

  • ●DNA degradation
  • ●Sample contamination
  • ●Incorrect sample type

Compare With Similar Tests

TestCDON Gene Holoprosencephaly type 11 NGS Genetic TestWhole Exome SequencingChromosomal Microarray
ComparisonCDON Gene Holoprosencephaly type 11 NGS Genetic Test

Frequently Asked Questions

What is CDON Gene Holoprosencephaly Type 11?
Holoprosencephaly type 11 is a rare genetic disorder caused by mutations in the CDON gene, affecting brain and face development.
What are the symptoms of HPE11?
Symptoms include facial abnormalities, delayed development, seizures, feeding difficulties, and organ abnormalities.
How is the test performed?
The test uses next-generation sequencing to analyze DNA from a blood sample for mutations in the CDON gene.
What is the cost of the test?
The test costs INR 20000 at DNA Labs India.
Is home sample collection available?
Yes, free home sample collection is available across India for online bookings.
How long does it take to get results?
Results are typically available within 3 to 4 weeks.
What does a positive result mean?
A positive result confirms the presence of a pathogenic CDON gene mutation, indicating HPE11.
Can this test be used for prenatal diagnosis?
It may be used in prenatal settings with appropriate samples, but genetic counseling is essential.
Is genetic counseling required?
Yes, genetic counseling is recommended before and after testing to understand implications.
What are the treatment options for HPE11?
Treatment is supportive and may include therapies for symptoms, but there is no cure; management focuses on improving quality of life.
How accurate is the NGS test?
The NGS test is highly accurate for detecting mutations in the CDON gene, but no test is 100% infallible.
Who should consider this test?
Individuals with symptoms of HPE11, a family history of the condition, or prenatal concerns should consider this test.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

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Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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