CFH Gene Hemolytic uremic syndrome NGS Genetic Test
Short Name: CFH Gene HUS NGS Test
Also known as: CFH Gene Mutation Test for HUS, Complement Factor H Genetic Test, Atypical HUS Genetic Test
CFH Gene Hemolytic uremic syndrome NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
To identify genetic mutations in the CFH gene associated with Hemolytic Uremic Syndrome (HUS), aiding in diagnosis, personalized treatment planning, and family risk assessment.
- Test Code
- 5412
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
Consult with a healthcare provider or genetic counselor to discuss test implications. No specific preparation is required, but ensure accurate medical history is provided.
Method: Venipuncture or finger-prick
Laboratory Analysis
A blood sample will be drawn from a vein in the arm or a finger-prick for FTA card collection. The process is quick and minimally invasive.
Report Delivery
Apply pressure to the collection site to prevent bruising. Resume normal activities immediately. Results will be available online in 3-4 weeks.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
To identify genetic mutations in the CFH gene associated with Hemolytic Uremic Syndrome (HUS), aiding in diagnosis, personalized treatment planning, and family risk assessment.
How to Prepare
- Ensure the patient is relaxed and hydrated
- Use sterile equipment for blood collection
- Label samples correctly with patient details
- Store samples at ambient temperature as specified
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Genetic testing for CFH gene mutations is crucial for diagnosing atypical HUS and guiding targeted therapies like complement inhibitors, improving patient outcomes."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood samples
- Insufficient sample volume
- Incorrectly labeled or contaminated samples
Understanding Your Results
No pathogenic variants detected
Normal finding; CFH gene mutations are unlikely to be the cause of HUS symptoms. Further clinical evaluation may be needed.
Action: Consult with a nephrologist for alternative diagnoses.
Pathogenic variant(s) detected
Abnormal finding; indicates a genetic mutation in the CFH gene associated with increased risk of atypical HUS.
Action: Seek genetic counseling and discuss targeted treatments with a specialist.
If you experience symptoms like bloody diarrhea, reduced urine output, or unexplained fatigue, or if you have a family history of HUS, consult a nephrologist or genetic counselor promptly.
Limitations
- ⚠May not detect all rare or novel mutations in the CFH gene
- ⚠Results require interpretation by a genetic counselor or specialist
- ⚠Does not rule out other causes of HUS, such as infections or autoimmune disorders
Risks & Considerations
- ●Minor pain or bruising at the blood collection site
- ●Very low risk of infection or dizziness
- ●Potential psychological impact of genetic results
Interfering Factors
- ●Recent blood transfusions may affect DNA quality
- ●Sample contamination or improper storage
- ●Use of certain medications that alter DNA integrity
Frequently Asked Questions
What is the CFH Gene Hemolytic Uremic Syndrome NGS Genetic Test?
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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