CFI Gene Hemolytic uremic syndrome NGS Genetic Test
Short Name: CFI Gene HUS NGS Genetic Test
Also known as: CFI Gene Test for HUS, Complement Factor I Genetic Test, HUS Genetic Panel
CFI Gene Hemolytic uremic syndrome NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks from sample collection. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of the CFI Gene HUS NGS Genetic Test is to detect mutations in the CFI gene responsible for hemolytic uremic syndrome. This test aids in diagnosing atypical HUS, differentiating it from other forms of the disease, and guiding treatment decisions such as targeted therapy with complement inhibitors. It also provides essential information for genetic counseling and family risk assessment.
- Test Code
- 5421
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 weeks from sample collection
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No special preparation is required. Ensure to bring a valid ID and prescription if available.
Method: Venipuncture
Laboratory Analysis
A trained phlebotomist will collect a blood sample from a vein in your arm.
Report Delivery
Apply pressure to the puncture site with a cotton ball to stop bleeding. Avoid heavy lifting for a few hours.
Timeline: 3 to 4 weeks from sample collection
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the CFI Gene HUS NGS Genetic Test is to detect mutations in the CFI gene responsible for hemolytic uremic syndrome. This test aids in diagnosing atypical HUS, differentiating it from other forms of the disease, and guiding treatment decisions such as targeted therapy with complement inhibitors. It also provides essential information for genetic counseling and family risk assessment.
How to Prepare
- Stay hydrated before sample collection
- Wear loose clothing to allow easy access to the arm
- Inform the phlebotomist of any bleeding disorders or medications
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"This genetic test is essential for diagnosing atypical hemolytic uremic syndrome and can guide personalized treatment strategies, improving patient outcomes."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted sample
- Insufficient sample volume
- Incorrectly labeled sample
Understanding Your Results
Positive for pathogenic variant
Confirms a genetic cause for HUS. May indicate increased risk for family members and guide treatment with complement inhibitors.
Negative for pathogenic variant
No mutations detected in the CFI gene. HUS may be due to other genetic or non-genetic factors.
Variant of uncertain significance (VUS)
A genetic change was found, but its association with HUS is unclear. Further testing and clinical correlation are recommended.
If you experience symptoms of HUS such as bloody diarrhea, abdominal pain, or decreased urine output, or if you have a family history of the condition, consult a nephrologist or geneticist immediately.
Limitations
- ⚠Test only analyzes the CFI gene; other genes associated with HUS are not covered
- ⚠May not detect all types of mutations, such as large deletions or duplications
- ⚠Results should be interpreted in conjunction with clinical findings
Risks & Considerations
- ●Minimal risk associated with blood draw, such as bruising or soreness at the puncture site
- ●Rare risk of infection or excessive bleeding
Interfering Factors
- ●Sample contamination
- ●Degraded DNA
- ●Recent blood transfusion
Compare With Similar Tests
| Test | CFI Gene Hemolytic uremic syndrome NGS Genetic Test | Complement Factor H Gene Test | ADAMTS13 Activity Test | Stool Culture for E. coli |
|---|---|---|---|---|
| Comparison | CFI Gene Hemolytic uremic syndrome NGS Genetic Test |
Frequently Asked Questions
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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