ChIP Sequencing and Analysis Test
Short Name: ChIP-Seq
Also known as: ChIP Sequencing, Chromatin Immunoprecipitation Sequencing
ChIP Sequencing and Analysis Test test available at DNA Labs India for ₹32,000. Uses Chromatin Immunoprecipitation, Next-Generation Sequencing, Bioinformatics Analysis on Extracted DNA samples. Results in Results are typically available within 8 weeks after the sample reaches the laboratory.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
The purpose of ChIP sequencing is to identify the specific DNA regions where proteins of interest bind, providing insights into gene regulatory networks, histone modifications, and chromatin states. This information is crucial for understanding disease mechanisms, identifying biomarkers, and developing targeted therapies. In clinical settings, ChIP sequencing can help diagnose conditions caused by aberrant protein-DNA interactions, such as certain cancers and genetic disorders. It also aids in monitoring treatment response and discovering novel drug targets.
- Test Code
- 6356
- CPT Code
- 88384
- ICD Code
- Z01.89
- Price
- ₹32,000
- Sample Type
- Extracted DNA
- Result Time
- Results are typically available within 8 weeks after the sample reaches the laboratory.
- Fasting Required
- No
- Method
- Chromatin Immunoprecipitation, Next-Generation Sequencing, Bioinformatics Analysis
Sample Collection
No special preparation is required. Inform your healthcare provider about any medications or supplements you are taking.
Method: Blood or tissue sample
Laboratory Analysis
A blood sample will be drawn from a vein in your arm, or a tissue sample may be collected depending on the test requirement.
Report Delivery
You can resume normal activities immediately. If a tissue biopsy was performed, follow your doctor's post-procedure instructions.
Timeline: Results are typically available within 8 weeks after the sample reaches the laboratory.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of ChIP sequencing is to identify the specific DNA regions where proteins of interest bind, providing insights into gene regulatory networks, histone modifications, and chromatin states. This information is crucial for understanding disease mechanisms, identifying biomarkers, and developing targeted therapies. In clinical settings, ChIP sequencing can help diagnose conditions caused by aberrant protein-DNA interactions, such as certain cancers and genetic disorders. It also aids in monitoring treatment response and discovering novel drug targets.
How to Prepare
- Ensure the sample is collected in a sterile DNA LoBind tube
- Label the tube with patient ID and date of collection
- Transport the sample to the lab within 24 hours at 2-8°C
- Avoid repeated freeze-thaw cycles
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"ChIP sequencing provides critical insights into gene regulation mechanisms, aiding in the identification of therapeutic targets in cancer and other diseases."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood sample
- Insufficient DNA quantity (< 1 µg)
- DNA with A260/A280 ratio < 1.8
- Sample not stored at appropriate temperature
Understanding Your Results
Consult your healthcare provider if you have questions about your results or if you are considering this test for research or clinical purposes. Discuss the implications of the findings with a genetic counselor or specialist.
Limitations
- ⚠Requires high-quality DNA; degraded samples may yield poor results
- ⚠Antibody specificity is critical for accurate results
- ⚠Bioinformatics analysis requires expertise and may have interpretation variability
- ⚠Not a diagnostic test for a specific disease; results need clinical correlation
Risks & Considerations
- ●Minimal risk of bleeding or infection at the blood draw site
- ●If a biopsy is performed, there is a small risk of pain, bleeding, or infection
- ●No radiation exposure or other significant risks
Interfering Factors
- ●Poor quality or degraded DNA
- ●Insufficient amount of starting material
- ●Non-specific antibody binding
- ●Over-amplification during library preparation
- ●Contamination with RNA or proteins
Compare With Similar Tests
| Test | ChIP Sequencing and Analysis | Whole Genome Sequencing | RNA Sequencing | ATAC-seq | Methylation Sequencing |
|---|---|---|---|---|---|
| Comparison | ChIP Sequencing and Analysis |
Frequently Asked Questions
What is ChIP sequencing?
What is the cost of ChIP sequencing at DNA Labs India?
What sample is required for ChIP sequencing?
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What are the applications of ChIP sequencing?
Is fasting required before the ChIP sequencing test?
Can ChIP sequencing be used for disease diagnosis?
What is the difference between ChIP-seq and RNA-seq?
How should the DNA sample be stored?
Are there any risks associated with the test?
Do I need a doctor's prescription for ChIP sequencing?
Is home sample collection available for ChIP sequencing?
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Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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