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CLCNKA Gene Bartter syndrome type 4b NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

CLCNKA Gene Bartter syndrome type 4b NGS Genetic Test

Short Name: CLCNKA Gene Bartter Syndrome Type 4b NGS Test

Also known as: CLCNKA Gene Mutation Test, Bartter Syndrome Type 4b DNA Test, CLCNKA Genetic Analysis

CLCNKA Gene Bartter syndrome type 4b NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic TestAll Ages🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

The purpose of this test is to detect mutations in the CLCNKA gene to diagnose Bartter Syndrome Type 4b, enabling accurate treatment planning, genetic counseling, and family screening.

Test Code
2573
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

Provide clinical history and undergo genetic counseling to draw a pedigree chart.

Method: Venipuncture or FTA Card Spot

Step 2

Laboratory Analysis

Blood sample collected via venipuncture or one drop on FTA card under sterile conditions.

Step 3

Report Delivery

Apply pressure to the puncture site; store sample at ambient room temperature if needed.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Genetic counseling and clinical history review are required before sample collection.
2
During the Test:DNA extraction and next-generation sequencing are performed to analyze the CLCNKA gene.
3
After the Test:Results are reviewed by a geneticist, and a detailed report is provided with recommendations.

About This Test

Who Should Get This Test

The purpose of this test is to detect mutations in the CLCNKA gene to diagnose Bartter Syndrome Type 4b, enabling accurate treatment planning, genetic counseling, and family screening.

How to Prepare

  • Ensure patient identification
  • Use aseptic technique
  • Label samples correctly
  • Transport to lab promptly

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"This genetic test is essential for confirming Bartter Syndrome Type 4b, allowing for targeted treatment and genetic counseling to manage symptoms and prevent complications."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
ContainerEDTA Tube or FTA Card
Collection MethodVenipuncture or FTA Card Spot

Sample Stability

Sample Rejection Criteria:
  • Hemolyzed sample
  • Insufficient volume
  • Improper labeling
  • Contaminated sample

Understanding Your Results

Results indicate the presence or absence of pathogenic mutations in the CLCNKA gene. A positive result confirms Bartter Syndrome Type 4b, while a negative result may require further testing.
📊

Pathogenic variant detected

Confirms diagnosis of Bartter Syndrome Type 4b; recommend clinical management and genetic counseling.

📊

No pathogenic variant detected

Bartter Syndrome Type 4b unlikely; consider other genetic or clinical causes.

⚠️ When to Consult a Doctor:

Consult a healthcare provider if symptoms persist, for result interpretation, or to discuss treatment options and family planning.

Limitations

  • ⚠May not detect all types of mutations
  • ⚠Results require clinical correlation
  • ⚠Genetic counseling recommended for interpretation

Risks & Considerations

  • ●Minimal risk from blood draw, such as bruising or infection
  • ●Psychological impact of genetic results

Interfering Factors

  • ●Poor sample quality
  • ●Contamination during collection
  • ●Improper storage conditions

Compare With Similar Tests

TestCLCNKA Gene Bartter syndrome type 4b NGS Genetic TestCLCNKB Gene TestSLC12A1 Gene Test
ComparisonCLCNKA Gene Bartter syndrome type 4b NGS Genetic TestTests for mutations in the CLCNKB gene, associated with Bartter Syndrome Type 4a.Identifies mutations causing Bartter Syndrome Type 1.

Frequently Asked Questions

What is Bartter Syndrome Type 4b?
Bartter Syndrome Type 4b is a rare genetic disorder caused by mutations in the CLCNKA gene, affecting kidney function and leading to electrolyte imbalances.
What is the CLCNKA gene?
The CLCNKA gene provides instructions for making a protein that regulates chloride ion movement in the kidneys, and mutations cause Bartter Syndrome Type 4b.
What are the symptoms of Bartter Syndrome Type 4b?
Symptoms include excessive urination, excessive thirst, muscle weakness and cramps, fatigue, dehydration, low blood pressure, and delayed growth and development.
How is Bartter Syndrome Type 4b diagnosed?
Diagnosis is confirmed through genetic testing, such as the NGS Genetic Test for the CLCNKA gene, along with clinical evaluation.
What is the cost of the CLCNKA Gene Test?
The cost is INR 20000 at DNA Labs India, with free home sample collection available across India.
Is home sample collection available?
Yes, free home sample collection is offered for online bookings in numerous cities across India.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
What sample type is required?
Blood, extracted DNA, or one drop of blood on an FTA card can be used.
Is fasting required for this test?
No, fasting is not required for this genetic test.
Can this test be used for prenatal diagnosis?
Consult a genetic counselor for prenatal testing options, as this test may be applicable in certain cases.
What should I do if the test is positive?
A positive result confirms Bartter Syndrome Type 4b; consult a healthcare provider for treatment and genetic counseling.
Is genetic counseling included?
Yes, a genetic counseling session is included to draw a pedigree chart and discuss results.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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