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CORIN Gene Preeclampsia/eclampsia type 5 NGS Genetic Test

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CORIN Gene Preeclampsia/eclampsia type 5 NGS Genetic Test

Short Name: CORIN Gene Preeclampsia Test

Also known as: CORIN Gene Test for Preeclampsia, Preeclampsia Type 5 Genetic Screening, CORIN Mutation Analysis

CORIN Gene Preeclampsia/eclampsia type 5 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS), DNA Sequencing on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

Next-Generation Sequencing Genetic TestFemalePregnant Women (Reproductive Age)🏠 Home Collection

🩺 Medically Reviewed By

Overview

The purpose of this test is to detect mutations in the CORIN gene that are associated with an increased risk of preeclampsia and eclampsia type 5. It aids in early risk assessment, allowing for timely medical interventions and monitoring during pregnancy to prevent severe complications.

Test Code
5548
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS), DNA Sequencing
Step 1

Sample Collection

No special preparation such as fasting is required. Provide clinical history and undergo genetic counseling as recommended.

Method: Venipuncture or FTA Card

Step 2

Laboratory Analysis

A blood sample will be drawn from a vein in the arm, or a drop of blood will be collected on an FTA card. The procedure is quick and minimally invasive.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bleeding. Resume normal activities immediately. Store the sample as instructed for stability.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:No fasting required. Provide detailed clinical and family history during genetic counseling.
2
During the Test:Blood sample collection via venipuncture or FTA card. Procedure takes about 10-15 minutes.
3
After the Test:Resume normal activities. Results will be available online or via email/WhatsApp in 3-4 weeks.

About This Test

Who Should Get This Test

The purpose of this test is to detect mutations in the CORIN gene that are associated with an increased risk of preeclampsia and eclampsia type 5. It aids in early risk assessment, allowing for timely medical interventions and monitoring during pregnancy to prevent severe complications.

How to Prepare

  • Ensure proper patient identification
  • Use sterile collection equipment
  • Label samples accurately
  • Transport samples at ambient temperature unless specified

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Genetic testing for CORIN mutations can provide valuable insights for managing preeclampsia risks, especially in high-risk pregnancies. Early identification allows for tailored prenatal care."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Collection MethodVenipuncture or FTA Card

Sample Stability

Blood sample at room temperature
Extracted DNA at -20°C
Sample Rejection Criteria:
  • Hemolyzed or clotted blood sample
  • Insufficient sample volume
  • Improper labeling or documentation
  • Contaminated sample

Understanding Your Results

Results indicate the presence or absence of pathogenic mutations in the CORIN gene. A positive result suggests an increased genetic risk for preeclampsia, while a negative result indicates lower risk based on this gene.
📊

Positive (Pathogenic variant detected)

Increased risk for preeclampsia/eclampsia. Consult healthcare provider for enhanced monitoring and management.

📊

Negative (No pathogenic variant detected)

Lower genetic risk based on CORIN gene. Continue standard prenatal care and monitor for symptoms.

📊

Variant of uncertain significance (VUS)

Genetic variant found but clinical significance unknown. Further testing or family studies may be recommended.

⚠️ When to Consult a Doctor:

Consult your obstetrician or genetic counselor immediately if you experience symptoms of preeclampsia (e.g., severe headaches, vision changes, abdominal pain) or if test results are positive for risk assessment.

Limitations

  • May not detect all genetic variants associated with preeclampsia
  • Results should be interpreted in conjunction with clinical findings
  • Not a standalone diagnostic tool; requires clinical correlation
  • Limited to CORIN gene mutations; other genetic factors not assessed

Risks & Considerations

  • Minor bruising or discomfort at blood draw site
  • Rare risk of infection or fainting
  • Emotional impact of genetic results

Interfering Factors

  • Sample contamination
  • Improper sample storage or handling
  • Recent blood transfusion
  • DNA degradation

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ComparisonCORIN Gene Preeclampsia/eclampsia type 5 NGS Genetic Test

Frequently Asked Questions

What is the CORIN Gene Preeclampsia/Eclampsia Type 5 NGS Genetic Test?
It is a non-invasive genetic test that analyzes DNA for mutations in the CORIN gene, which are linked to an increased risk of preeclampsia and eclampsia during pregnancy.
Who should consider this test?
Pregnant women with a family history of preeclampsia, previous pregnancy complications, or symptoms like high blood pressure and proteinuria should consider this test.
How is the test performed?
The test requires a blood sample or a drop of blood on an FTA card, which is analyzed using Next-Generation Sequencing technology.
Is fasting required before the test?
No, fasting is not required. You can eat and drink normally before sample collection.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
What does a positive result mean?
A positive result indicates a pathogenic mutation in the CORIN gene, suggesting an increased genetic risk for preeclampsia. Consult your doctor for management options.
Is the test covered by insurance?
Coverage varies by insurance provider. It is advisable to check with your insurer directly. DNA Labs India offers the test at INR 20000.
Are there any risks associated with the test?
The test involves a simple blood draw with minimal risks such as bruising. Genetic results may have emotional implications, so counseling is recommended.
Can this test diagnose preeclampsia?
No, this test assesses genetic risk. Preeclampsia is diagnosed based on clinical symptoms, blood pressure, and urine protein tests.
What is the cost of the test?
The test costs INR 20000, which includes sample collection, analysis, and report generation.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for online bookings across many cities in India.
How accurate is the test?
The test uses advanced NGS technology for high accuracy in detecting CORIN gene mutations, but results should be interpreted alongside clinical findings.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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