Skip to main content
DNA Labs India

DIABLO Gene Deafness, autosomal dominant type 64 NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

DIABLO Gene Deafness, autosomal dominant type 64 NGS Genetic Test

Short Name: DIABLO Gene Deafness NGS Test

Also known as: DIABLO-related deafness, Autosomal dominant deafness type 64

DIABLO Gene Deafness, autosomal dominant type 64 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Reports available in 3 to 4 weeks after sample collection.. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

To diagnose DIABLO gene mutations causing autosomal dominant deafness type 64, enabling accurate clinical management and genetic counseling.

Test Code
2316
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
Reports available in 3 to 4 weeks after sample collection.
Fasting Required
No
Method
Next Generation Sequencing (NGS)
Step 1

Sample Collection

Pre-test genetic counseling to discuss family history, risks, and benefits of testing. Ensure clinical history of the patient is reviewed.

Method: Standard phlebotomy or FTA card collection

Step 2

Laboratory Analysis

Blood sample drawn via venipuncture or blood spot collected on FTA card. Minimal discomfort similar to standard blood tests.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bruising. Resume normal activities unless otherwise directed.

Timeline: Reports available in 3 to 4 weeks after sample collection.

Patient Instructions

1
Before the Test:Genetic counseling session to draw a pedigree chart of family members affected with deafness. Review clinical history and symptoms.
2
During the Test:Sample collection (blood or FTA card) and sent to lab for NGS analysis.
3
After the Test:Wait for 3-4 weeks for report. Follow up with genetic counselor or physician for result interpretation.

About This Test

Who Should Get This Test

To diagnose DIABLO gene mutations causing autosomal dominant deafness type 64, enabling accurate clinical management and genetic counseling.

How to Prepare

  • Fast for 4-6 hours if required by lab protocol
  • Avoid strenuous activity before sample collection
  • Bring identification and prescription if available

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"Early genetic testing for DIABLO gene deafness can aid in timely management and family planning. Consult a genetic counselor for personalized advice."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Collection MethodStandard phlebotomy or FTA card collection

Sample Stability

Sample Rejection Criteria:
  • Hemolyzed or contaminated samples
  • Insufficient sample volume
  • Improperly labeled samples

Understanding Your Results

Results indicate the presence or absence of pathogenic variants in the DIABLO gene. Positive results confirm genetic deafness, while negative results may suggest other causes.
📊

Positive

Pathogenic variant detected; confirms diagnosis of DIABLO gene deafness

Action: Consult geneticist for management and family testing

📊

Negative

No pathogenic variant detected

Action: Consider other genetic or non-genetic causes; further evaluation may be needed

📊

Variant of Uncertain Significance

Genetic change found but clinical significance unclear

Action: Repeat testing or family studies recommended

⚠️ When to Consult a Doctor:

If you experience unexplained hearing loss, tinnitus, dizziness, or have a family history of genetic deafness, consult an ENT specialist or geneticist for evaluation.

Limitations

  • ⚠May not detect all types of mutations, such as large deletions
  • ⚠Results require interpretation by a genetic specialist
  • ⚠Does not assess for other genetic or environmental causes of deafness

Risks & Considerations

  • ●Psychological impact of positive results
  • ●Potential for insurance or discrimination issues (though not covered in India)
  • ●Minimal physical risks from blood draw

Interfering Factors

  • ●Poor sample quality
  • ●Contamination during DNA extraction
  • ●Technical errors in NGS sequencing

Compare With Similar Tests

TestDIABLO Gene Deafness, autosomal dominant type 64 NGS Genetic TestGJB2 Gene TestSLC26A4 Gene Test
ComparisonDIABLO Gene Deafness, autosomal dominant type 64 NGS Genetic Test

Frequently Asked Questions

What is DIABLO gene deafness?
It is a rare genetic condition causing hearing loss due to mutations in the DIABLO gene, inherited in an autosomal dominant pattern.
How is DIABLO gene deafness inherited?
Autosomal dominant inheritance means if one parent has the mutation, there is a 50% chance of passing it to each child.
What are the common symptoms?
Symptoms include hearing loss, tinnitus, difficulty understanding speech, sensitivity to noise, and vertigo.
How is the test performed?
The test uses Next Generation Sequencing (NGS) to analyze DNA from a blood sample or FTA card.
Is fasting required for the test?
No, fasting is not required for this genetic test.
What is the cost of the test?
The test costs INR 20000, including free home sample collection in many Indian cities.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
Is genetic counseling necessary?
Yes, genetic counseling is recommended before and after testing to discuss implications and support.
Can the test detect all mutations?
While NGS is highly accurate, it may not detect all mutation types, such as large deletions.
What if the test result is positive?
A positive result confirms genetic deafness; consult a geneticist for management and family testing options.
Is the test covered by insurance?
Generally, genetic testing is not covered by most insurance plans in India; patients may need to pay out of pocket.
Where can I get this test done?
The test is available across India with free home collection in cities like Mumbai, Delhi, Bangalore, and more.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

Related Tests

Connexin 30 Mutation Detection Test

₹8,000

COL4A3 Gene Alport syndrome, autosomal recessive NGS Genetic Test

₹20,000

PLCB4 Gene Auriculocondylar syndrome type 2 NGS Genetic Test

₹20,000

DIAPH3 Gene Auditory neuropathy, autosomal dominant NGS Genetic Test

₹20,000

MYO7A Gene Deafness, autosomal dominant type 11 NGS Genetic Test

₹20,000

POU4F3 Gene Deafness, autosomal dominant type 15 NGS Genetic Test

₹20,000
For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

Book Your Test

Enter your details and we'll connect you within 15 minutes.

🧬

Quick Connect

Enter your mobile number and we’ll connect you with the team.

+91

✅ Connecting you now...

🔒 Your number is used to respond to this request.