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DNA Labs India

DNA Extraction from Plasma or Serum Test

DNA Labs India | ISO 9001:2015 Certified

DNA Extraction from Plasma or Serum Test

Short Name: DNA Extraction

Also known as: Plasma DNA Extraction, Serum DNA Extraction, cfDNA Extraction

DNA Extraction from Plasma or Serum Test test available at DNA Labs India for ₹1,800. Uses Phenol-Chloroform Extraction, Column-based Purification on Plasma or Serum samples. Results in Reports are typically available within 5 days after sample collection. You will be notified via email or SMS once the report is ready.. Free home collection in 300+ cities across India.

Molecular🏠 Home Collection

🩺 Medically Reviewed By

Overview

The primary purpose of DNA extraction from plasma or serum is to obtain purified DNA for molecular testing. This includes identifying genetic mutations associated with hereditary disorders, detecting oncogenic mutations in cancer patients (liquid biopsy), monitoring minimal residual disease, and diagnosing infectious diseases by detecting pathogen DNA. The extracted DNA can be used for various applications such as next-generation sequencing, real-time PCR, and microarray analysis. Early detection and precise diagnosis facilitated by this test can guide treatment decisions and improve patient outcomes.

Test Code
6328
CPT Code
83890
ICD Code
Z01.89
Price
₹1,800
Sample Type
Plasma or Serum
Result Time
Reports are typically available within 5 days after sample collection. You will be notified via email or SMS once the report is ready.
Fasting Required
No
Method
Phenol-Chloroform Extraction, Column-based Purification
Step 1

Sample Collection

No special preparation required. Inform your doctor about any medications or supplements you are taking.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample will be drawn from a vein in your arm. The procedure is quick and minimally invasive.

Step 3

Report Delivery

You can resume normal activities immediately. There may be slight bruising at the puncture site, which resolves on its own.

Timeline: Reports are typically available within 5 days after sample collection. You will be notified via email or SMS once the report is ready.

Patient Instructions

1
Before the Test:No special preparation is required. However, it is important to inform your healthcare provider about any ongoing treatments or medical conditions.
2
During the Test:A blood sample will be collected by a trained phlebotomist. The process takes only a few minutes.
3
After the Test:You can leave immediately after sample collection. No restrictions on diet or activity.

About This Test

Who Should Get This Test

The primary purpose of DNA extraction from plasma or serum is to obtain purified DNA for molecular testing. This includes identifying genetic mutations associated with hereditary disorders, detecting oncogenic mutations in cancer patients (liquid biopsy), monitoring minimal residual disease, and diagnosing infectious diseases by detecting pathogen DNA. The extracted DNA can be used for various applications such as next-generation sequencing, real-time PCR, and microarray analysis. Early detection and precise diagnosis facilitated by this test can guide treatment decisions and improve patient outcomes.

How to Prepare

  • Use EDTA tube for plasma or SST for serum
  • Mix gently after collection
  • Transport to lab within 2 hours at 2-8°C
  • Avoid hemolysis

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"DNA extraction from plasma or serum is a crucial step for various molecular diagnostics, including liquid biopsy and genetic screening. Proper handling ensures accurate downstream analysis."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypePlasma or Serum
Sample Volume2-3 mL
ContainerEDTA tube (plasma) or SST (serum)
Collection MethodVenipuncture

Sample Stability

Plasma/Serum: 24 hours at 2-8°C
Extracted DNA: 1 week at -20°C
Long-term storage: -80°C
Sample Rejection Criteria:
  • Hemolyzed sample
  • Clotted sample
  • Incorrect tube
  • Improper labeling

Understanding Your Results

The results of DNA extraction are typically reported as the quantity and purity of the extracted DNA. Adequate DNA yield and purity are essential for successful downstream testing. The interpretation is usually performed by a molecular biologist or geneticist in the context of the specific test being conducted.
📊

Sufficient DNA for most downstream applications

📊

Good purity, minimal protein contamination

📊

High molecular weight DNA, suitable for long-read sequencing

⚠️ When to Consult a Doctor:

If you are experiencing any of the symptoms mentioned in the indications, or if your doctor has recommended DNA extraction for diagnostic purposes, it is advisable to consult with a qualified healthcare professional to understand the need and implications of the test.

Limitations

  • Low cfDNA concentration in some conditions
  • May not detect all mutations due to sensitivity limits
  • Requires specialized equipment and expertise

Risks & Considerations

  • Minimal risk of bleeding or bruising at the puncture site
  • Rare risk of infection
  • Dizziness or fainting during blood draw

Interfering Factors

  • Hemolysis of sample
  • Improper storage temperature
  • Delayed processing
  • Contamination during collection

Compare With Similar Tests

TestDNA Extraction from Plasma or Serum
ComparisonDNA Extraction from Plasma or Serum

Frequently Asked Questions

What is DNA extraction from plasma or serum?
It is a laboratory process to isolate DNA from the cell-free fraction of blood (plasma or serum) for molecular testing.
Why is this test needed?
It is used for detecting genetic mutations, diagnosing infections, and monitoring cancer treatment response.
Is fasting required before the test?
No, fasting is not required for DNA extraction from plasma or serum.
What sample is needed?
A blood sample collected in an EDTA tube (for plasma) or SST (for serum).
How long does the test take?
The turnaround time is 5 days.
Is home sample collection available?
Yes, we offer free home sample collection for online bookings across many cities in India.
What is the cost of the test?
The cost is INR 1800, which is all-inclusive with no hidden charges.
Are there any risks associated with the test?
The test involves a simple blood draw, which carries minimal risks like slight bruising or infection.
Can this test detect cancer?
It can detect circulating tumor DNA, which may indicate the presence of cancer, but it is not a standalone diagnostic test.
How should the sample be stored?
Plasma or serum should be stored at 2-8°C if processed within 24 hours, otherwise frozen at -20°C.
What is the difference between plasma and serum?
Plasma is the liquid component of blood containing anticoagulants, while serum is the liquid remaining after blood clotting. Both can be used for DNA extraction.
Will I get a report?
Yes, you will receive a detailed report with DNA quantity and purity, which can be accessed online or via email.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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