DNA Extraction from Swab or Filter Test
Short Name: DNA Extraction
Also known as: DNA isolation from buccal swab, DNA extraction from filter paper, Genetic material extraction
DNA Extraction from Swab or Filter Test test available at DNA Labs India for ₹1,800. Uses Phenol-chloroform extraction, Silica column-based purification on Buccal Swab samples. Results in 5-7 business days after sample receipt at the laboratory.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
The primary purpose of DNA extraction is to obtain pure, high-quality DNA from a biological sample for subsequent genetic analysis. This may be needed for: 1) Confirming a suspected genetic disorder, 2) Determining biological relationships (paternity/maternity), 3) Assessing genetic predisposition to certain diseases, 4) Guiding personalized treatment (pharmacogenomics), 5) Carrier screening for inherited conditions, 6) Forensic or legal identification. The extracted DNA can be used for PCR, sequencing, microarray, or other molecular assays.
- Test Code
- 6327
- CPT Code
- 83890
- ICD Code
- Z01.89
- Price
- ₹1,800
- Sample Type
- Buccal Swab
- Result Time
- 5-7 business days after sample receipt at the laboratory.
- Fasting Required
- No
- Method
- Phenol-chloroform extraction, Silica column-based purification
Sample Collection
Avoid eating, drinking, or smoking for at least 30 minutes before sample collection. Do not use mouthwash or chew gum.
Method: Buccal swab
Laboratory Analysis
The swab will be rubbed gently on the inside of the cheek for about 30 seconds. The procedure is painless and non-invasive.
Report Delivery
No special precautions are needed. You can resume normal activities immediately.
Timeline: 5-7 business days after sample receipt at the laboratory.
Patient Instructions
About This Test
Who Should Get This Test
The primary purpose of DNA extraction is to obtain pure, high-quality DNA from a biological sample for subsequent genetic analysis. This may be needed for: 1) Confirming a suspected genetic disorder, 2) Determining biological relationships (paternity/maternity), 3) Assessing genetic predisposition to certain diseases, 4) Guiding personalized treatment (pharmacogenomics), 5) Carrier screening for inherited conditions, 6) Forensic or legal identification. The extracted DNA can be used for PCR, sequencing, microarray, or other molecular assays.
How to Prepare
- Do not touch the swab tip with fingers.
- Ensure the swab is dry before placing it in the transport tube.
- Label the sample with your name and date of birth.
- Use the prepaid envelope provided for shipping.
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"DNA extraction is the foundational step for accurate genetic analysis. Proper sample collection and handling are critical to avoid contamination and ensure reliable results."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Sample with visible contamination (food particles, blood)
- Swab without sufficient cellular material
- Sample received in broken or leaking container
- Unlabeled or mislabeled sample
Understanding Your Results
Adequate for most molecular assays; proceed with testing.
May be insufficient for some tests; consider re-collection.
Pure DNA; no significant protein contamination.
Possible protein contamination; may affect downstream results.
If you are experiencing unexplained symptoms such as chronic fatigue, recurrent infections, or unexplained weight loss, consult a healthcare professional. They can determine if genetic testing is appropriate and guide you on the next steps.
Limitations
- ⚠DNA extraction alone does not provide diagnostic results; further testing is required.
- ⚠Low yield may occur in elderly or severely dehydrated individuals.
- ⚠Filter paper samples may have lower DNA yield compared to fresh swabs.
- ⚠Results depend on sample quality and proper collection technique.
Risks & Considerations
- ●No significant risks associated with buccal swab collection.
- ●Minor discomfort or gagging may occur in some individuals.
- ●Rarely, bleeding if the cheek is accidentally scratched.
Interfering Factors
- ●Contamination with food particles or saliva
- ●Improper storage of swab (exposure to heat or moisture)
- ●Insufficient cell collection
- ●Use of expired collection kit
- ●Cross-contamination during handling
Compare With Similar Tests
| Test | DNA Extraction from Swab or Filter | |||
|---|---|---|---|---|
| Comparison | DNA Extraction from Swab or Filter |
Frequently Asked Questions
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