Skip to main content
DNA Labs India

DSC3 Gene Hypotrichosis and recurrent skin vesicles NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

DSC3 Gene Hypotrichosis and recurrent skin vesicles NGS Genetic Test

Short Name: DSC3 Gene Test

Also known as: DSC3 gene hypotrichosis test, DSC3 mutation analysis, Genetic test for skin blistering

DSC3 Gene Hypotrichosis and recurrent skin vesicles NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To identify mutations in the DSC3 gene for accurate diagnosis of hypotrichosis and recurrent skin vesicles, enabling personalized treatment and management strategies.

Test Code
4976
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

Clinical history review and genetic counselling session to draw a pedigree chart.

Method: Venipuncture or FTA card blood drop

Step 2

Laboratory Analysis

Blood sample collected via venipuncture or one drop on FTA card.

Step 3

Report Delivery

Sample transported to laboratory for NGS analysis.

Timeline: 3 to 4 weeks

Patient Instructions

1
Before the Test:Genetic counselling and clinical history review are required before sample collection.
2
During the Test:Sample collection and processing in the laboratory using NGS technology.
3
After the Test:Report generation, delivery, and follow-up consultation if needed.

About This Test

Who Should Get This Test

To identify mutations in the DSC3 gene for accurate diagnosis of hypotrichosis and recurrent skin vesicles, enabling personalized treatment and management strategies.

How to Prepare

  • Ensure proper sample labeling
  • Avoid hemolysis in blood samples
  • Follow aseptic techniques

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Early genetic testing for DSC3 mutations can guide management and improve quality of life for affected individuals."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Collection MethodVenipuncture or FTA card blood drop

Sample Stability

Blood samples stable at ambient temperature for 48 hours
FTA cards stable at room temperature
Sample Rejection Criteria:
  • Hemolyzed samples
  • Insufficient sample volume
  • Improperly labeled samples

Understanding Your Results

Results indicate the presence or absence of pathogenic mutations in the DSC3 gene, guiding diagnosis and management.
📊

Positive for pathogenic variant

Confirms diagnosis of DSC3-related condition; genetic counselling recommended.

📊

Negative for pathogenic variant

No mutation detected; consider other genetic or non-genetic causes.

📊

Variant of uncertain significance

Further testing or family studies may be needed for clarification.

⚠️ When to Consult a Doctor:

If symptoms persist, worsen, or if there is a family history of genetic skin disorders, consult a dermatologist or geneticist.

Limitations

  • ⚠May not detect all genetic variants
  • ⚠Results require clinical correlation

Risks & Considerations

  • ●Minor bruising at blood draw site
  • ●Rare risk of infection

Interfering Factors

  • ●Sample contamination
  • ●Improper sample storage

Frequently Asked Questions

What is the DSC3 gene test?
It is a genetic test using NGS to detect mutations in the DSC3 gene, which causes hypotrichosis and recurrent skin vesicles.
What are the symptoms of DSC3 gene hypotrichosis?
Symptoms include sparse or absent hair on the scalp and body, and recurrent painful skin blisters.
How is the test performed?
A blood sample or extracted DNA is analyzed using next-generation sequencing technology.
What is the cost of the test?
The test costs INR 20000 at DNA Labs India, with free home sample collection.
Is home collection available?
Yes, free home sample collection is available across many cities in India.
How long does it take to get results?
Results are typically available in 3 to 4 weeks.
What does a positive result mean?
A positive result confirms a pathogenic mutation in the DSC3 gene, indicating the genetic condition.
Is the test covered by insurance?
Coverage depends on your insurance plan; check with your provider.
Who should take this test?
Individuals with symptoms like sparse hair or recurrent skin blisters, or with a family history of such conditions.
What is the accuracy of NGS testing?
NGS is highly accurate for detecting genetic mutations, including small DNA variations.
Are there any risks associated with the test?
Risks are minimal, such as minor bruising from blood draw.
How can I prepare for the test?
Provide clinical history and attend a genetic counselling session before sample collection.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

Related Tests

Nx Gen Sequencing: Albinism Test

₹28,665

ADAR Gene Dyschromatosis Symmetrica Hereditaria NGS Genetic Test

₹20,000

COL7A1 Gene Epidermolysis bullosa dystrophica NGS Genetic Test

₹20,000

KRT14 Gene Epidermolysis bullosa simplex, Dowling-Meara type NGS Genetic Test

₹20,000

LAMA3 Gene Epidermolysis bullosa, generalized atrophic benign NGS Genetic Test

₹20,000

ENPP1 Gene Cole disease NGS Genetic Test

₹20,000
For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

Book Your Test

Enter your details and we'll connect you within 15 minutes.

🧬

Quick Connect

Enter your mobile number and we’ll connect you with the team.

+91

✅ Connecting you now...

🔒 Your number is used to respond to this request.