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DSP Gene Keratosis palmoplantaris striata type 2 NGS Genetic Test

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DSP Gene Keratosis palmoplantaris striata type 2 NGS Genetic Test

Short Name: DSP Gene KPS Type 2 NGS Test

Also known as: Desmoplakin Gene Mutation, Keratosis Palmoplantaris Striata Type 2

DSP Gene Keratosis palmoplantaris striata type 2 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS (Next-Generation Sequencing) on Blood, Extracted DNA, or FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.

NGS Genetic TestAll Ages🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To identify mutations in the DSP gene for diagnosis of Keratosis Palmoplantaris Striata Type 2.

Test Code
5045
Price
₹20,000
Sample Type
Blood, Extracted DNA, or FTA Card
Result Time
3 to 4 weeks
Fasting Required
No
Method
NGS (Next-Generation Sequencing)
Step 1

Sample Collection

No specific preparation required. Provide clinical history and family pedigree.

Method: Venipuncture or finger prick

Step 2

Laboratory Analysis

Blood sample will be collected by a trained phlebotomist.

Step 3

Report Delivery

Apply pressure to the puncture site. Store sample as instructed.

Timeline: 3 to 4 weeks

Patient Instructions

1
Before the Test:Consult with a genetic counselor or dermatologist.
2
During the Test:Sample collection and processing in the lab.
3
After the Test:Report generation and consultation for results.

About This Test

Who Should Get This Test

To identify mutations in the DSP gene for diagnosis of Keratosis Palmoplantaris Striata Type 2.

How to Prepare

  • Fast for 8-12 hours if required, but not specified
  • Bring identification and prescription
  • Inform about any medications

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Early genetic diagnosis of DSP can help in managing symptoms and providing genetic counseling for families."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood, Extracted DNA, or FTA Card
Sample Volume5 mL blood or equivalent
ContainerEDTA tube or FTA card
Collection MethodVenipuncture or finger prick

Sample Stability

Blood sample stable for 48 hours at room temperature
FTA card stable for years
Sample Rejection Criteria:
  • Hemolyzed sample
  • Insufficient volume
  • Incorrect labeling

Understanding Your Results

Results indicate the presence or absence of mutations in the DSP gene.
📊

Mutation detected

Confirms diagnosis of Keratosis Palmoplantaris Striata Type 2. Genetic counseling recommended.

📊

No mutation detected

Does not rule out other genetic causes. Clinical correlation advised.

⚠️ When to Consult a Doctor:

If symptoms persist or worsen, or for genetic counseling after test results.

Limitations

  • ⚠May not detect all mutations
  • ⚠Requires genetic counseling for interpretation
  • ⚠Not a diagnostic tool for all skin conditions

Risks & Considerations

  • ●Minimal risk from blood draw
  • ●Psychological impact of genetic results

Interfering Factors

  • ●Contaminated sample
  • ●Degraded DNA
  • ●Incorrect sample type

Compare With Similar Tests

TestDSP Gene Keratosis palmoplantaris striata type 2 NGS Genetic TestSanger SequencingWhole Exome Sequencing
ComparisonDSP Gene Keratosis palmoplantaris striata type 2 NGS Genetic Test

Frequently Asked Questions

What is DSP Gene Keratosis Palmoplantaris Striata Type 2?
It is a rare genetic skin disorder caused by mutations in the DSP gene, leading to thick, scaly patches on palms and soles.
What are the symptoms of this condition?
Symptoms include thick, scaly skin on palms and soles, pain, cracking, bleeding, and difficulty walking or using hands.
How is DSP diagnosed?
Diagnosis involves clinical evaluation, skin biopsy, and genetic testing such as NGS to identify DSP gene mutations.
What is an NGS Genetic Test?
Next-generation sequencing (NGS) is a technology that sequences multiple genes simultaneously to detect genetic mutations efficiently.
What is the cost of this test?
The cost is INR 20000, which includes sample collection, testing, and reporting.
Is home sample collection available?
Yes, free home collection is offered across India for online bookings.
How long does it take to get results?
Results are typically available in 3 to 4 weeks.
Is the test painful?
The test involves a blood draw, which may cause minimal discomfort, but it is generally not painful.
Can children undergo this test?
Yes, the test is suitable for all ages, but genetic counseling is recommended for minors.
What if the test is positive?
A positive result confirms the diagnosis, and genetic counseling should be sought for management and family planning.
Is genetic counseling included?
Yes, the test package includes a genetic counseling report to help interpret results.
How accurate is the test?
NGS is highly accurate for detecting known mutations, but it may not identify all genetic variations.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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