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DNA Labs India

EGF Gene Hypomagnesemia type 4 NGS Genetic Test

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EGF Gene Hypomagnesemia type 4 NGS Genetic Test

Short Name: EGF Gene Hypomagnesemia Type 4 Test

Also known as: EGF-related hypomagnesemia, Hypomagnesemia with secondary hypocalcemia type 4

EGF Gene Hypomagnesemia type 4 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

Next-Generation Sequencing (NGS)🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

The purpose of this test is to diagnose EGF Gene Hypomagnesemia Type 4 by detecting mutations in the EGF gene using NGS technology, enabling early intervention and personalized treatment planning.

Test Code
2113
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

No special preparation required. Ensure clinical history and family pedigree chart are documented during genetic counseling.

Method: Venipuncture or FTA card spotting

Step 2

Laboratory Analysis

A blood sample will be collected via venipuncture or a drop of blood on an FTA card by a trained phlebotomist.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bruising. Resume normal activities immediately.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Genetic counseling session to discuss symptoms, family history, and test implications.
2
During the Test:Blood sample collection and DNA extraction for NGS analysis.
3
After the Test:Report generation and consultation with a healthcare provider to discuss results and management options.

About This Test

Who Should Get This Test

The purpose of this test is to diagnose EGF Gene Hypomagnesemia Type 4 by detecting mutations in the EGF gene using NGS technology, enabling early intervention and personalized treatment planning.

How to Prepare

  • Use sterile equipment for blood collection
  • Label samples correctly with patient details
  • Transport samples at ambient temperature to the lab

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Early genetic testing for EGF Gene Hypomagnesemia Type 4 is crucial for managing symptoms and preventing complications. Consult a genetic counselor for personalized care."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume3-5 mL of blood
ContainerEDTA tube or FTA card
Collection MethodVenipuncture or FTA card spotting

Sample Stability

Up to 7 days at room temperature
Stable for months at room temperature
Sample Rejection Criteria:
  • Hemolyzed or clotted blood samples
  • Insufficient sample volume
  • Incorrect labeling or missing documentation

Understanding Your Results

Results indicate the presence or absence of pathogenic variants in the EGF gene. A positive result confirms EGF Gene Hypomagnesemia Type 4, while a negative result may require further genetic testing if symptoms persist.
📊

Positive for pathogenic variant

Confirms diagnosis of EGF Gene Hypomagnesemia Type 4; recommend genetic counseling and management

📊

Negative for pathogenic variant

No mutations detected in the EGF gene; consider other genetic or non-genetic causes

📊

Variant of uncertain significance

Further evaluation needed; clinical correlation recommended

⚠️ When to Consult a Doctor:

Consult a doctor if you experience symptoms like chronic low magnesium, seizures, or developmental delays, or if there is a family history of hypomagnesemia.

Limitations

  • ⚠This test only detects mutations in the EGF gene; other genetic causes of hypomagnesemia may require additional tests
  • ⚠Results do not predict disease severity or progression
  • ⚠No cure is available; management focuses on symptom relief

Risks & Considerations

  • ●Minor pain or bruising at the blood draw site
  • ●Very low risk of infection
  • ●Emotional impact of genetic testing results

Interfering Factors

  • ●Contaminated or degraded DNA samples
  • ●Improper sample collection or storage
  • ●Recent blood transfusions may affect DNA analysis

Frequently Asked Questions

What is EGF Gene Hypomagnesemia Type 4?
It is a rare genetic disorder caused by mutations in the EGF gene, leading to impaired magnesium regulation and symptoms like low magnesium levels, weakness, and seizures.
How is this test performed?
The test uses Next-Generation Sequencing (NGS) to analyze DNA from a blood sample for mutations in the EGF gene.
What is the cost of the test?
The EGF Gene Hypomagnesemia Type 4 NGS Genetic Test costs INR 20000, inclusive of home sample collection in India.
Is home sample collection available?
Yes, free home sample collection is offered across many cities in India for online bookings.
What are the symptoms that indicate the need for this test?
Symptoms include chronic low magnesium, fatigue, seizures, developmental delays, irregular heartbeat, and bone abnormalities.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
Is fasting required before the test?
No, fasting is not required. The test can be done at any time without special preparation.
What does a positive result mean?
A positive result confirms the presence of pathogenic EGF gene mutations, diagnosing EGF Gene Hypomagnesemia Type 4.
Is there a cure for this condition?
There is no cure, but symptoms can be managed with magnesium supplements and supportive therapies under medical guidance.
Who should get this test?
Individuals with symptoms of hypomagnesemia, family history of the disorder, or those seeking genetic diagnosis for management.
How accurate is this genetic test?
NGS technology provides high accuracy for detecting mutations, but results should be interpreted by a healthcare professional.
Can this test be done for prenatal diagnosis?
Prenatal testing may be possible; consult a genetic counselor or obstetrician for appropriate options.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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