Epstein-Barr Virus Antibody to Nuclear Antigen (EBNA) IgG Test
Short Name: EBNA IgG Test
Also known as: EBV Antibody Test, EBNA IgG Antibody Test, Epstein-Barr Nuclear Antigen IgG Test
Epstein-Barr Virus Antibody to Nuclear Antigen (EBNA) IgG Test test available at DNA Labs India for ₹13,000. Uses Immunoassay on Serum samples. Results in Reports are typically available within 2-3 weeks after sample collection.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Kothari Ramesh Shantilal
Consultant Microbiologist · Reg: 27670
Last reviewed: September 7, 2026
Overview
The EBNA IgG test is used to detect antibodies to the Epstein-Barr virus nuclear antigen, helping to confirm past infection with EBV, assess immune status, and differentiate from other infections with similar symptoms.
- Test Code
- 528
- Price
- ₹13,000
- Sample Type
- Serum
- Result Time
- Reports are typically available within 2-3 weeks after sample collection.
- Fasting Required
- No
- Method
- Immunoassay
Sample Collection
Ensure a duly filled Test Send Out Consent Form (Form 35) is completed and signed.
Method: Venipuncture
Laboratory Analysis
A blood sample will be drawn from a vein in your arm by a trained phlebotomist.
Report Delivery
Apply pressure to the puncture site with a cotton ball to prevent bruising and resume normal activities.
Timeline: Reports are typically available within 2-3 weeks after sample collection.
Patient Instructions
About This Test
Who Should Get This Test
The EBNA IgG test is used to detect antibodies to the Epstein-Barr virus nuclear antigen, helping to confirm past infection with EBV, assess immune status, and differentiate from other infections with similar symptoms.
How to Prepare
- Collect 2 mL serum from 1 SST tube (0.5 mL minimum)
- Ship samples refrigerated or frozen as per stability guidelines
- Duly filled Test Send Out Consent Form (Form 35) is mandatory
Doctor's Notes
Reviewed by Dr Kothari Ramesh Shantilal — MBBS, MD (Microbiology) · Reg. No. 27670
"The EBNA IgG test is essential for confirming past EBV infection and is recommended for patients with symptoms like fatigue or sore throat, or those at risk of complications."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or lipemic samples
- Insufficient sample volume
- Missing or incomplete consent form
Understanding Your Results
Positive
Indicates past EBV infection; antibodies are present, suggesting immune response to the virus.
Negative
No detectable EBNA IgG antibodies, suggesting no past infection or early infection stage before antibody development.
Equivocal
Borderline results may require repeat testing or correlation with other EBV antibody tests.
Consult a doctor if the test is positive and you have symptoms like persistent fatigue, or if symptoms persist despite a negative result, for further evaluation and management.
Limitations
- ⚠Cannot distinguish between active and past infection
- ⚠May be negative in early stages of EBV infection
- ⚠Results must be interpreted alongside clinical symptoms and other tests
Risks & Considerations
- ●Minor bruising or pain at the puncture site
- ●Rare risk of infection or fainting
- ●Dizziness during blood draw
Interfering Factors
- ●Hemolyzed or lipemic samples may affect accuracy
- ●Recent blood transfusion or immunoglobulin therapy
- ●Cross-reactivity with other herpes virus antibodies
Compare With Similar Tests
| Test | Epstein-Barr Virus Antibody to Nuclear Antigen (EBNA) IgG Test | EBV VCA IgG Test | EBV VCA IgM Test | Monospot Test | Complete Blood Count (CBC) |
|---|---|---|---|---|---|
| Comparison | Epstein-Barr Virus Antibody to Nuclear Antigen (EBNA) IgG Test | Detects antibodies to viral capsid antigen; rises early in infection, while EBNA IgG appears later. | Indicates recent or acute infection; EBNA IgG suggests past infection. | Rapid test for heterophile antibodies; less specific than EBNA IgG for EBV confirmation. | Supportive test showing lymphocytosis or atypical lymphocytes in EBV infection. |
Frequently Asked Questions
What is the EBNA IgG test?
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