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ERCC5 Gene Xeroderma pigmentosum, group G NGS Genetic Test

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ERCC5 Gene Xeroderma pigmentosum, group G NGS Genetic Test

Also known as: XP-G Genetic Test, ERCC5 Gene Mutation Analysis

ERCC5 Gene Xeroderma pigmentosum, group G NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic TestAll Ages🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

The purpose of the ERCC5 Gene Xeroderma pigmentosum, group G NGS Genetic Test is to identify mutations in the ERCC5 gene for diagnosing Xeroderma pigmentosum, group G (XP-G), a rare genetic disorder. This test helps confirm the diagnosis in individuals with symptoms of XP, guides treatment and management strategies, and informs family planning through genetic counseling.

Test Code
5179
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

Clinical history review and genetic counseling session recommended to draw a pedigree chart of family members affected with Xeroderma pigmentosum.

Method: Blood draw or FTA card collection

Step 2

Laboratory Analysis

Sample collection via blood draw or one drop of blood on an FTA card, performed by a trained phlebotomist.

Step 3

Report Delivery

Sample is sent to the laboratory for next-generation sequencing analysis; results are available in 3 to 4 weeks.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Undergo genetic counseling and provide detailed clinical and family history. No fasting is required.
2
During the Test:A blood sample or FTA card collection will be taken by a healthcare professional.
3
After the Test:Wait for 3 to 4 weeks for results. Discuss findings with a geneticist or referring specialist for management guidance.

About This Test

Who Should Get This Test

The purpose of the ERCC5 Gene Xeroderma pigmentosum, group G NGS Genetic Test is to identify mutations in the ERCC5 gene for diagnosing Xeroderma pigmentosum, group G (XP-G), a rare genetic disorder. This test helps confirm the diagnosis in individuals with symptoms of XP, guides treatment and management strategies, and informs family planning through genetic counseling.

How to Prepare

  • Provide clinical history of the patient
  • Ensure genetic counseling session is completed
  • Collect blood sample or use FTA card as specified
  • Label samples correctly with patient details

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Collection MethodBlood draw or FTA card collection

Understanding Your Results

Results from the ERCC5 Gene Xeroderma pigmentosum, group G NGS Genetic Test indicate the presence or absence of mutations in the ERCC5 gene. Interpretation should be done by a qualified geneticist or healthcare provider.
📊

Positive for pathogenic ERCC5 mutation

Confirms diagnosis of Xeroderma pigmentosum, group G (XP-G). Recommend sun protection, regular skin cancer screening, and genetic counseling for family members.

📊

Negative for pathogenic ERCC5 mutation

No mutations detected in the ERCC5 gene. Does not rule out other forms of XP or genetic conditions; clinical correlation and further testing may be needed.

📊

Variant of uncertain significance (VUS)

A genetic variant was found but its clinical significance is unknown. Recommend follow-up testing, family studies, and consultation with a genetic specialist.

⚠️ When to Consult a Doctor:

Consult a dermatologist or genetic counselor if you or a family member experience symptoms of Xeroderma pigmentosum, such as severe sun sensitivity, blistering after sun exposure, or a history of skin cancer, to discuss the need for genetic testing.

Risks & Considerations

  • ●Minor bruising or discomfort at the blood collection site
  • ●Rare risk of infection at the puncture site

Frequently Asked Questions

What is the ERCC5 Gene Xeroderma pigmentosum, group G NGS Genetic Test?
This test uses next-generation sequencing to detect mutations in the ERCC5 gene, which causes Xeroderma pigmentosum, group G (XP-G), a rare genetic disorder affecting DNA repair.
What are the symptoms of Xeroderma pigmentosum, group G?
Symptoms include severe sun sensitivity, blistering and peeling of skin after sun exposure, freckling, eye problems like photophobia, and an increased risk of skin cancer.
How is the test performed?
The test analyzes blood or DNA samples using NGS technology to identify mutations in the ERCC5 gene.
What is the cost of the ERCC5 Gene test?
The cost is INR 20000, with free home sample collection available across India.
How long does it take to get results?
Results are typically available in 3 to 4 weeks after sample collection.
Is home sample collection available?
Yes, free home collection is offered for online bookings in numerous cities across India.
What should I do before the test?
Provide clinical history and undergo genetic counseling to draw a family pedigree chart. No fasting is required.
What do positive results mean?
Positive results confirm a diagnosis of XP-G, indicating mutations in the ERCC5 gene. This guides management like sun protection and cancer screening.
Are there any risks associated with the test?
Risks are minimal, such as minor bruising from blood draw. The test itself has no significant medical risks.
Is the test covered by insurance?
Coverage depends on your insurance plan; it is not universally covered. Check with your provider for details.
Who should consider this test?
Individuals with symptoms of XP, a family history of the disorder, or clinical suspicion based on dermatological evaluation should consider this test.
Where can I get this test done?
The test is available through DNA Labs India with home collection in cities like Mumbai, Delhi, Bangalore, and many others across India.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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