Skip to main content
DNA Labs India

ERF Gene Craniosynostosis type 4 NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

ERF Gene Craniosynostosis type 4 NGS Genetic Test

Short Name: ERF Craniosynostosis Type 4 Test

Also known as: ERF Gene Test for Craniosynostosis, Craniosynostosis Type 4 Genetic Test, ERF Mutation Analysis

ERF Gene Craniosynostosis type 4 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS, Next-Generation Sequencing on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3-4 weeks. Free home collection in 300+ cities across India.

NGS Genetic TestPediatric🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

The purpose of this test is to identify mutations in the ERF gene for the diagnosis of Craniosynostosis type 4, enabling early intervention and personalized treatment plans.

Test Code
2706
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3-4 weeks
Fasting Required
No
Method
NGS, Next-Generation Sequencing
Step 1

Sample Collection

No special preparation required. Bring a valid ID and any relevant medical records.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample will be drawn from a vein in the arm by a trained phlebotomist.

Step 3

Report Delivery

Apply pressure to the puncture site to stop bleeding. Resume normal activities.

Timeline: 3-4 weeks

Patient Instructions

1
Before the Test:Genetic counseling session to discuss family history and test implications.
2
During the Test:Blood sample collection and DNA extraction for NGS analysis.
3
After the Test:Report delivery and follow-up counseling based on results.

About This Test

Who Should Get This Test

The purpose of this test is to identify mutations in the ERF gene for the diagnosis of Craniosynostosis type 4, enabling early intervention and personalized treatment plans.

How to Prepare

  • Bring identification and doctor's prescription
  • Wear loose clothing for easy access to arm
  • Inform staff of any bleeding disorders or medications

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Early genetic testing for craniosynostosis can guide treatment decisions and improve long-term outcomes for affected children."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
ContainerEDTA tube for blood
Collection MethodVenipuncture

Sample Stability

Room temperature48 hours
Refrigerated7 days
Sample Rejection Criteria:
  • Hemolyzed sample
  • Insufficient volume
  • Contaminated sample
  • Incorrect labeling

Understanding Your Results

Results indicate the presence or absence of pathogenic variants in the ERF gene. A positive result confirms a genetic diagnosis, while a negative result may require further testing.
Positive: Pathogenic variant detected – consult a geneticist for management.
Negative: No pathogenic variants – consider other genetic or environmental causes.
Variant of uncertain significance – genetic counseling recommended for further evaluation.
⚠️ When to Consult a Doctor:

Consult a doctor if results are positive, if symptoms persist despite negative results, or for genetic counseling and family planning.

Limitations

  • ⚠May not detect all genetic variants
  • ⚠Requires genetic counseling for interpretation
  • ⚠Results are not diagnostic alone and should be correlated with clinical findings

Risks & Considerations

  • ●Minimal risk from blood draw, such as bruising or infection
  • ●Psychological impact of genetic results

Interfering Factors

  • ●Sample contamination
  • ●Degraded DNA
  • ●Hemolyzed blood sample
  • ●Incorrect sample storage

Compare With Similar Tests

TestERF Gene Craniosynostosis type 4 NGS Genetic TestFGFR Gene Craniosynostosis TestWhole Exome Sequencing
ComparisonERF Gene Craniosynostosis type 4 NGS Genetic Test

Frequently Asked Questions

What is the ERF Gene Craniosynostosis Type 4 NGS Genetic Test?
It is a genetic test that uses next-generation sequencing to identify mutations in the ERF gene, which causes Craniosynostosis type 4.
How is the test performed?
A blood sample is collected and analyzed using NGS technology to detect ERF gene mutations.
What is the cost of the test?
The test costs INR 20000, with free home sample collection available across India.
How long does it take to get results?
Results are typically available within 3-4 weeks after sample collection.
Is the test painful?
The test involves a standard blood draw, which may cause minor discomfort but is generally not painful.
Who should get this test?
Infants or children with symptoms of craniosynostosis, such as abnormal head shape, developmental delays, or seizures, and those with a family history.
What are the symptoms of Craniosynostosis type 4?
Symptoms include abnormal head shape, developmental delays, intellectual disability, and seizures.
Can this test detect other genetic conditions?
No, this test specifically targets the ERF gene for Craniosynostosis type 4.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for this test across India.
What should I do if the test is positive?
Consult a geneticist or pediatric specialist for further evaluation, treatment options, and genetic counseling.
Is genetic counseling required before the test?
Yes, a genetic counseling session is recommended to discuss family history, test implications, and interpretation of results.
How accurate is the NGS genetic test?
NGS technology is highly accurate for detecting genetic mutations, but results should be interpreted in conjunction with clinical findings.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

Related Tests

Amino Acids Qualitative Two Dimensional Urine Test

₹1,439

Succinylacetone Urine Test

₹5,000

RXFP2 Gene Cryptorchidism NGS Genetic Test

₹20,000

EFNB1 Gene Craniofrontonasal syndrome NGS Genetic Test

₹20,000

MNX1 Gene Currarino syndrome NGS Genetic Test

₹20,000

FGFR1 Gene Craniosynostosis, FGFR1 related NGS Genetic Test

₹20,000
For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

Book Your Test

Enter your details and we'll connect you within 15 minutes.

🧬

Quick Connect

Enter your mobile number and we’ll connect you with the team.

+91

✅ Connecting you now...

🔒 Your number is used to respond to this request.