Eukaryotic SmallRNA Sequencing and Analysis Test
Short Name: SmallRNA Seq
Also known as: Small RNA Sequencing, miRNA Sequencing, sRNA-Seq
Eukaryotic SmallRNA Sequencing and Analysis Test test available at DNA Labs India for ₹38,000. Uses Next-Generation Sequencing (NGS), Bioinformatics Analysis on Extracted DNA samples. Results in Reports are typically delivered within 8 weeks after sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
The primary purpose of eukaryotic smallRNA sequencing is to comprehensively profile small RNA molecules in a biological sample. This helps in understanding gene regulatory networks, identifying biomarkers for early disease detection, monitoring disease progression, and evaluating response to therapy. It is also used in research to discover novel small RNAs and study their functional roles.
- Test Code
- 6428
- CPT Code
- 81445
- ICD Code
- Z01.89
- Price
- ₹38,000
- Sample Type
- Extracted DNA
- Result Time
- Reports are typically delivered within 8 weeks after sample receipt.
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS), Bioinformatics Analysis
Sample Collection
No special preparation is required. However, inform your doctor about any medications or supplements you are taking. Avoid alcohol and strenuous exercise for 24 hours prior to sample collection.
Method: Blood draw or tissue biopsy
Laboratory Analysis
A blood sample will be drawn from a vein in your arm. If a tissue biopsy is required, it will be performed by a qualified professional. The procedure is quick and minimally invasive.
Report Delivery
You can resume normal activities immediately. There may be slight bruising at the puncture site, which is normal. Your sample will be processed in the laboratory.
Timeline: Reports are typically delivered within 8 weeks after sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
The primary purpose of eukaryotic smallRNA sequencing is to comprehensively profile small RNA molecules in a biological sample. This helps in understanding gene regulatory networks, identifying biomarkers for early disease detection, monitoring disease progression, and evaluating response to therapy. It is also used in research to discover novel small RNAs and study their functional roles.
How to Prepare
- Use RNAse-free collection tubes
- For blood, use EDTA or PAXgene tubes
- For tissue, place in RNA later or snap-freeze in liquid nitrogen
- Label the sample with patient ID and date
- Transport on dry ice if possible
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"Small RNA profiling is emerging as a powerful tool for early cancer detection and monitoring therapeutic response. This test provides comprehensive data that can guide personalized treatment strategies."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Sample with visible hemolysis
- Insufficient RNA quantity (< 100 ng)
- RNA integrity number (RIN) < 7
- Improper labeling or missing requisition form
Understanding Your Results
Upregulation of oncogenic miRNAs (e.g., miR-21)
May suggest active malignancy; further evaluation needed
Downregulation of tumor suppressor miRNAs (e.g., miR-34a)
Could indicate poor prognosis or aggressive disease
Presence of viral-encoded small RNAs
Suggests active viral infection
Novel small RNA candidates
May represent new biomarkers; requires validation
If you have received this test as part of a diagnostic workup, consult your referring physician to discuss the results. If you are experiencing symptoms such as unexplained weight loss, persistent fatigue, or neurological deficits, seek medical advice promptly.
Limitations
- ⚠Requires high-quality RNA; degraded samples may yield poor results
- ⚠Bioinformatics analysis may not detect very low abundance small RNAs
- ⚠Interpretation requires correlation with clinical findings
- ⚠Not a standalone diagnostic test; results should be used with other investigations
Risks & Considerations
- ●Minimal risk of bleeding or infection at the blood draw site
- ●Rare risk of nerve injury during blood draw
- ●For biopsy: risk of bleeding, infection, or organ damage (rare)
Interfering Factors
- ●RNA degradation due to improper handling
- ●Contamination with genomic DNA
- ●Hemolysis in blood samples
- ●Recent chemotherapy or radiation therapy
- ●Concurrent use of certain medications
Compare With Similar Tests
| Test | Eukaryotic SmallRNA Sequencing and Analysis | Whole Exome Sequencing | mRNA Sequencing | Microarray |
|---|---|---|---|---|
| Comparison | Eukaryotic SmallRNA Sequencing and Analysis |
Frequently Asked Questions
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Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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