Eukaryotic Transcriptome Sequencing and Reference Based Analysis-Including lncRNA Test
Short Name: Transcriptome Sequencing lncRNA
Also known as: Transcriptome Sequencing, RNA-seq with lncRNA Analysis, Whole Transcriptome Sequencing
Eukaryotic Transcriptome Sequencing and Reference Based Analysis-Including lncRNA Test test available at DNA Labs India for ₹48,000. Uses Next-Generation Sequencing (NGS), Reference-based transcriptome analysis, lncRNA annotation on Extracted RNA samples. Results in Results are typically available within 8 weeks after the sample reaches the laboratory.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of eukaryotic transcriptome sequencing with reference-based analysis is to comprehensively characterize the RNA landscape of a sample. This includes identifying differentially expressed genes, detecting alternative splicing events, and quantifying lncRNA expression. It is used in research to understand disease mechanisms, discover biomarkers, and identify therapeutic targets. In clinical settings, it can aid in the diagnosis of genetic disorders, particularly those involving splicing defects or aberrant gene expression.
- Test Code
- 6423
- CPT Code
- 81450
- ICD Code
- Z01.89
- Price
- ₹48,000
- Sample Type
- Extracted RNA
- Result Time
- Results are typically available within 8 weeks after the sample reaches the laboratory.
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS), Reference-based transcriptome analysis, lncRNA annotation
Sample Collection
No specific preparation required. However, inform your healthcare provider about any medications or supplements you are taking.
Method: Blood or tissue sample
Laboratory Analysis
A blood sample will be drawn from a vein in your arm. For tissue samples, a biopsy may be performed.
Report Delivery
You can resume normal activities immediately. The sample will be processed in the laboratory.
Timeline: Results are typically available within 8 weeks after the sample reaches the laboratory.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of eukaryotic transcriptome sequencing with reference-based analysis is to comprehensively characterize the RNA landscape of a sample. This includes identifying differentially expressed genes, detecting alternative splicing events, and quantifying lncRNA expression. It is used in research to understand disease mechanisms, discover biomarkers, and identify therapeutic targets. In clinical settings, it can aid in the diagnosis of genetic disorders, particularly those involving splicing defects or aberrant gene expression.
How to Prepare
- Ensure the sample is collected in the provided sterile container
- For blood samples, use EDTA tube
- For tissue samples, place in RNA later or snap-freeze
- Label the sample with patient ID and date
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"Transcriptome sequencing provides a dynamic view of gene expression, crucial for understanding disease mechanisms and identifying potential therapeutic targets."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed blood sample
- Insufficient quantity
- Improper labeling
- Sample not stored at appropriate temperature
Understanding Your Results
May indicate activation of a pathway or disease association
Potential biomarker or therapeutic target
May be involved in tumor suppression
Loss of function may contribute to oncogenesis
May produce altered protein
Could be pathogenic if it disrupts protein function
If you have a family history of genetic disorders or if your healthcare provider recommends transcriptome analysis for diagnostic purposes, consult a geneticist or specialist.
Limitations
- ⚠Reference-based analysis may miss novel transcripts not present in the reference
- ⚠Lowly expressed genes may not be detected due to sequencing depth
- ⚠Bioinformatics analysis requires expertise and may have false positives
- ⚠Clinical interpretation of lncRNA data is still evolving
Risks & Considerations
- ●Minimal risk of bleeding or infection at the blood draw site
- ●For tissue biopsy, there is a small risk of bleeding or infection
Interfering Factors
- ●RNA degradation due to improper sample handling
- ●Contamination with genomic DNA
- ●Low RNA yield or poor quality
- ●Batch effects in sequencing
- ●Reference genome mismatches
Compare With Similar Tests
| Test | Eukaryotic Transcriptome Sequencing and Reference Based Analysis-Including lncRNA | Whole Exome Sequencing | Microarray |
|---|---|---|---|
| Comparison | Eukaryotic Transcriptome Sequencing and Reference Based Analysis-Including lncRNA | WES focuses on protein-coding regions, while transcriptome sequencing captures all RNA, including non-coding. | Microarray measures known transcripts, while RNA-seq can detect novel transcripts and splice variants. |
Frequently Asked Questions
What is the cost of the test?
What sample is required?
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Is home sample collection available?
What is lncRNA?
Can this test diagnose cancer?
What is reference-based analysis?
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Is the test NABL accredited?
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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