Factor V Mutation Screening (F5 - G1691A) Test
Short Name: Factor V Mutation Screening
Also known as: F5 G1691A Mutation Test, Factor V Leiden Mutation Screening
Factor V Mutation Screening (F5 - G1691A) Test test available at DNA Labs India for ₹6,000. Uses Real Time PCR on Peripheral blood samples. Results in 3-4 days. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of Factor V Mutation Screening is to detect the G1691A mutation in the Factor V gene, which is associated with an increased risk of venous thromboembolism. This test helps in diagnosing hereditary thrombophilia, guiding treatment decisions, and implementing preventive measures for at-risk individuals.
- Test Code
- 3000
- Price
- ₹6,000
- Sample Type
- Peripheral blood
- Result Time
- 3-4 days
- Fasting Required
- No
- Method
- Real Time PCR
Sample Collection
No specific preparation is required. Bring a doctor's prescription if applicable, and inform the healthcare provider about any medications or recent medical procedures.
Method: Venipuncture
Laboratory Analysis
A blood sample will be drawn from a vein in your arm using a needle. The process is quick and typically takes a few minutes.
Report Delivery
Apply pressure to the puncture site to prevent bleeding. You may resume normal activities immediately.
Timeline: 3-4 days
Patient Instructions
About This Test
Who Should Get This Test
The purpose of Factor V Mutation Screening is to detect the G1691A mutation in the Factor V gene, which is associated with an increased risk of venous thromboembolism. This test helps in diagnosing hereditary thrombophilia, guiding treatment decisions, and implementing preventive measures for at-risk individuals.
How to Prepare
- No fasting required for this test
- Bring a valid doctor's prescription if available, though it may not be required for certain cases like surgery or pregnancy planning
- Inform the phlebotomist about any recent blood transfusions or medications
- Stay hydrated and wear loose clothing for easy access to the arm
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"This test is crucial for individuals with a family history of blood clots or unexplained thrombotic events, aiding in early intervention and risk management."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood sample
- Incorrect sample type or container
- Insufficient sample volume
- Labeled incorrectly or missing patient information
Understanding Your Results
Mutation Detected
Indicates an increased risk of developing blood clots. Consult a doctor for further evaluation, lifestyle advice, and possible anticoagulant therapy.
No Mutation Detected
Suggests a lower genetic risk for Factor V Leiden-related thrombophilia, but other risk factors may still be present. Discuss with a healthcare provider for comprehensive assessment.
Consult a doctor if you have symptoms of blood clots (e.g., pain, swelling, chest pain), a family history of thrombophilia, or if you are planning surgery or pregnancy. Also, seek medical advice after receiving test results for personalized management.
Limitations
- ⚠This test only screens for the G1691A mutation and may not detect other rare Factor V mutations
- ⚠Does not assess other genetic or acquired causes of thrombophilia
- ⚠Results should be interpreted in conjunction with clinical history and other tests
Risks & Considerations
- ●Minor bruising or pain at the puncture site
- ●Rare risk of infection or excessive bleeding
- ●Fainting or dizziness in some individuals
Interfering Factors
- ●Recent blood transfusions or bone marrow transplants may interfere with test results
- ●Contamination of the sample
- ●Certain medications affecting DNA integrity
Compare With Similar Tests
| Test | Factor V Mutation Screening (F5 - G1691A) | Prothrombin Gene Mutation Test | Antithrombin III Activity Test | Protein C and S Assay |
|---|---|---|---|---|
| Comparison | Factor V Mutation Screening (F5 - G1691A) | Screens for the G20210A mutation in the prothrombin gene, another common cause of thrombophilia. | Measures antithrombin III levels, which if low, can increase clotting risk. | Evaluates protein C and S deficiencies, which are natural anticoagulants. |
Frequently Asked Questions
What is Factor V Mutation Screening?
Why is this test done?
How is the test performed?
What does a positive result mean?
What are the risks of the test?
How long does it take to get results?
Is fasting required for this test?
Can this test be done at home?
What is the cost of the test?
Is the test covered by insurance?
What should I do if I have a family history of blood clots?
How accurate is the test?
Related Tests
Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
Book Your Test
Enter your details and we'll connect you within 15 minutes.