FGF10 Gene LADD syndrome NGS Genetic Test
Short Name: FGF10 LADD NGS
Also known as: LADD syndrome genetic test, FGF10 gene mutation test, NGS genetic test for LADD syndrome
FGF10 Gene LADD syndrome NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Reports are typically available within 3 to 4 weeks after the sample reaches the laboratory.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of this test is to identify pathogenic mutations in the FGF10 gene that are associated with LADD syndrome. This helps in confirming a clinical diagnosis, enabling early intervention, and providing accurate genetic counseling for affected individuals and their families.
- Test Code
- 5816
- CPT Code
- 81407
- ICD Code
- Q87.8
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- Reports are typically available within 3 to 4 weeks after the sample reaches the laboratory.
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No special preparation is required. However, a genetic counseling session is recommended before the test to discuss the implications and obtain informed consent.
Method: Venipuncture or Fingerstick
Laboratory Analysis
Blood sample is collected by a trained phlebotomist using sterile techniques. For FTA card, a few drops of blood are placed on the card and allowed to dry.
Report Delivery
No specific precautions. The sample is transported to the laboratory at ambient temperature.
Timeline: Reports are typically available within 3 to 4 weeks after the sample reaches the laboratory.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to identify pathogenic mutations in the FGF10 gene that are associated with LADD syndrome. This helps in confirming a clinical diagnosis, enabling early intervention, and providing accurate genetic counseling for affected individuals and their families.
How to Prepare
- For blood sample: Use EDTA tube, mix gently.
- For FTA card: Apply blood drops to the designated circles, air dry for at least 30 minutes.
- Label the sample with patient's name, date, and unique ID.
- Transport to the lab within 24-48 hours at room temperature.
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"LADD syndrome is a rare autosomal dominant disorder. Early genetic confirmation is crucial for management and family counseling."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood sample
- Insufficient sample volume
- Improper labeling
- Sample received after prolonged delay without proper storage
Understanding Your Results
Positive for pathogenic variant
Confirms diagnosis of LADD syndrome. Genetic counseling and family screening recommended.
Negative for pathogenic variant
No mutation detected in FGF10. Clinical diagnosis may still be considered if symptoms are strong; consider testing other genes.
Variant of uncertain significance (VUS)
A genetic variant was found but its clinical significance is unknown. Further segregation analysis or functional studies may be needed.
If you or your child have symptoms suggestive of LADD syndrome, or if there is a family history, consult a clinical geneticist or pediatrician for evaluation and genetic testing.
Limitations
- ⚠NGS may not detect large deletions/duplications or deep intronic variants.
- ⚠Variant of uncertain significance (VUS) may be reported; further testing may be needed.
- ⚠This test only analyzes the FGF10 gene, not other genes associated with similar phenotypes.
- ⚠Genetic counseling is recommended to interpret results in the context of family history.
Risks & Considerations
- ●Minimal risk of bruising or infection at the blood draw site
- ●Psychological impact of receiving genetic results
- ●Potential for incidental findings
Interfering Factors
- ●Contamination of sample with foreign DNA
- ●Insufficient DNA quantity or quality
- ●Presence of maternal cell contamination in prenatal samples
- ●Recent blood transfusion (within 2 weeks) may dilute nucleated cells
Compare With Similar Tests
| Test | FGF10 Gene LADD syndrome NGS Genetic Test | Whole Exome Sequencing (WES) | Targeted FGF10 Sanger Sequencing |
|---|---|---|---|
| Comparison | FGF10 Gene LADD syndrome NGS Genetic Test |
Frequently Asked Questions
What is LADD syndrome?
How is LADD syndrome diagnosed?
What is the cost of the FGF10 gene NGS test in India?
What sample is required for the test?
How long does it take to get results?
Is fasting required before the test?
Can the test be done on children?
Is home sample collection available?
What does a positive result mean?
What if the result is negative?
Are there any risks associated with the test?
Is the test covered by insurance?
Related Tests
Amino Acids Qualitative Two Dimensional Urine Test
₹1,439Succinylacetone Urine Test
₹5,000RXFP2 Gene Cryptorchidism NGS Genetic Test
₹20,000EFNB1 Gene Craniofrontonasal syndrome NGS Genetic Test
₹20,000MNX1 Gene Currarino syndrome NGS Genetic Test
₹20,000FGFR1 Gene Craniosynostosis, FGFR1 related NGS Genetic Test
₹20,000Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
Book Your Test
Enter your details and we'll connect you within 15 minutes.