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FLNA Gene Otopaladigital syndrome type 2 NGS Genetic Test

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FLNA Gene Otopaladigital syndrome type 2 NGS Genetic Test

Short Name: FLNA Gene OPD2 NGS Test

Also known as: Otopaladigital Syndrome Type 2, OPD2

FLNA Gene Otopaladigital syndrome type 2 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS, Next-Generation Sequencing on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3-4 weeks from sample receipt at the laboratory.. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To diagnose Otopaladigital Syndrome Type 2 by identifying mutations in the FLNA gene using NGS technology.

Test Code
2342
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3-4 weeks from sample receipt at the laboratory.
Fasting Required
No
Method
NGS, Next-Generation Sequencing
Step 1

Sample Collection

Genetic counseling session recommended to understand test implications and draw a pedigree chart of family history.

Method: Venipuncture

Step 2

Laboratory Analysis

Blood sample collected via venipuncture or alternative methods as specified, such as FTA card.

Step 3

Report Delivery

Sample processed for DNA extraction and NGS analysis in the laboratory.

Timeline: 3-4 weeks from sample receipt at the laboratory.

Patient Instructions

1
Before the Test:Genetic counseling session to review clinical history and family pedigree.
2
During the Test:Blood sample collection and laboratory processing for NGS analysis.
3
After the Test:Report generation, counseling session to discuss results, and management options.

About This Test

Who Should Get This Test

To diagnose Otopaladigital Syndrome Type 2 by identifying mutations in the FLNA gene using NGS technology.

How to Prepare

  • Ensure proper labeling of sample with patient details
  • Follow aseptic techniques during collection
  • Transport sample at specified ambient temperature if not using FTA card

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Consult a genetic counselor for personalized advice on OPD2 diagnosis and management."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Collection MethodVenipuncture

Sample Stability

Blood sample stable at room temperature for 24 hours
Extracted DNA stable at -20°C for long-term storage
FTA card samples stable at room temperature
Sample Rejection Criteria:
  • Hemolyzed or clotted sample
  • Insufficient volume or degraded DNA
  • Improper storage or labeling

Understanding Your Results

Results indicate the presence or absence of pathogenic variants in the FLNA gene, aiding in diagnosis of OPD2.
📊

Positive for pathogenic variant

Confirms diagnosis of Otopaladigital Syndrome Type 2. Genetic counseling and clinical management advised.

📊

Negative

No pathogenic variants detected in the FLNA gene. Clinical correlation recommended if symptoms persist.

📊

Variant of uncertain significance

Further testing, family studies, or functional analysis may be needed for clarification.

⚠️ When to Consult a Doctor:

If symptoms of OPD2 are present, such as skeletal anomalies or hearing loss, or if there is a family history of genetic disorders, consult a genetic specialist or healthcare provider.

Limitations

  • ⚠Cannot detect all types of mutations
  • ⚠May not identify mosaicism
  • ⚠Results may require confirmatory testing

Risks & Considerations

  • ●Minimal risk from blood draw, such as bruising or infection
  • ●Psychological impact of genetic results on patient and family

Interfering Factors

  • ●Poor sample quality
  • ●Contamination of DNA sample
  • ●Technical errors in sequencing

Frequently Asked Questions

What is the FLNA Gene Otopaladigital Syndrome Type 2 NGS Genetic Test?
It is a genetic test that uses Next-Generation Sequencing to analyze the FLNA gene for mutations causing OPD2, a rare skeletal disorder.
How much does the test cost at DNA Labs India?
The test costs INR 20000, with home sample collection available across India.
What are the common symptoms of Otopaladigital Syndrome Type 2?
Symptoms include scoliosis, short stature, polydactyly or syndactyly, hearing loss, and craniofacial abnormalities.
How is OPD2 inherited?
OPD2 follows an X-linked dominant inheritance pattern, meaning it can be passed from an affected mother to her children.
What sample types are accepted for the test?
Blood, extracted DNA, or one drop of blood on an FTA card are accepted.
How long does it take to receive the test results?
Results are typically available in 3-4 weeks from sample receipt.
Is home sample collection available for this test?
Yes, DNA Labs India offers free home sample collection for online bookings in numerous cities across India.
What is included in the test report?
The report includes clinical findings, raw data, FASTQ, and VCF files along with the conclusive genetic analysis.
How accurate is the NGS genetic test for OPD2?
NGS technology provides high accuracy in detecting gene mutations, but results may require clinical correlation and genetic counseling.
What should I do if I test positive for an FLNA mutation?
Consult a genetic counselor or specialist for personalized management and family planning advice.
Can children undergo this genetic test?
Yes, the test can be performed on individuals of all ages, including children, with appropriate consent and counseling.
Are there any risks associated with the test?
Risks are minimal, such as minor discomfort from blood draw, but genetic results may have psychological implications.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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