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Folate (Folic Acid) RBC Test

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Folate (Folic Acid) RBC Test

Short Name: Folate RBC Test

Also known as: Folic Acid RBC Test, RBC Folate Assay

Folate (Folic Acid) RBC Test test available at DNA Labs India for ₹3,500. Uses Chemiluminescent Immunoassay on Whole Blood and Serum samples. Results in Results are typically available on the same day if the sample is received by 2 PM.. Free home collection in 300+ cities across India.

Blood TestAll Ages🏠 Home Collection

🩺 Medically Reviewed By

Overview

The primary purpose of the Folate RBC Test is to diagnose folate deficiency by measuring the concentration of folate in red blood cells. It is used in the evaluation of anemia, particularly megaloblastic anemia, and to monitor the effectiveness of folate supplementation therapy.

Test Code
621
ICD Code
D52.9
Price
₹3,500
Sample Type
Whole Blood and Serum
Result Time
Results are typically available on the same day if the sample is received by 2 PM.
Fasting Required
No
Method
Chemiluminescent Immunoassay
Step 1

Sample Collection

No special preparation is needed. However, inform your healthcare provider about any medications or supplements you are taking.

Method: Venipuncture

Step 2

Laboratory Analysis

A phlebotomist will clean the area and insert a needle into a vein in your arm to collect blood samples into specified tubes.

Step 3

Report Delivery

Pressure will be applied to the puncture site with a cotton ball or bandage to prevent bleeding.

Timeline: Results are typically available on the same day if the sample is received by 2 PM.

Patient Instructions

1
Before the Test:No specific preparation required. Stay hydrated and wear loose clothing for easy blood draw.
2
During the Test:The blood collection process takes only a few minutes. You may feel a slight pinch when the needle is inserted.
3
After the Test:You can leave immediately after the test. Avoid heavy lifting with the arm used for blood draw for a few hours.

About This Test

Who Should Get This Test

The primary purpose of the Folate RBC Test is to diagnose folate deficiency by measuring the concentration of folate in red blood cells. It is used in the evaluation of anemia, particularly megaloblastic anemia, and to monitor the effectiveness of folate supplementation therapy.

How to Prepare

  • Collect 2 mL of whole blood in an EDTA (lavender top) tube
  • Collect 2 mL of serum in an SST tube
  • Wrap tubes in aluminium foil immediately to protect from light
  • Ship samples refrigerated or frozen as per instructions

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"The Folate RBC Test is essential for detecting long-term folate deficiency, which can prevent serious health issues like anemia and neural tube defects in pregnancy."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeWhole Blood and Serum
Sample Volume2 mL whole blood and 2 mL serum
ContainerLavender Top (EDTA) tube and SST
Collection MethodVenipuncture

Sample Stability

Room TemperatureNot Applicable
Refrigerated (2-8°C)24 hours
Frozen (-20°C)6 weeks
Sample Rejection Criteria:
  • Sample not in correct tube
  • Insufficient sample volume
  • Sample exposed to light
  • Hemolyzed or clotted sample

Understanding Your Results

Interpretation of RBC folate levels is based on established reference ranges to assess folate status.
📊

Folate deficiency indicated

Action: Further evaluation and possible supplementation recommended

Level: Below 150 ng/mL

📊

Normal folate status

Action: No intervention needed unless symptomatic

Level: 150-600 ng/mL

📊

Elevated folate levels

Action: May indicate high intake; review with healthcare provider

Level: Above 600 ng/mL

⚠️ When to Consult a Doctor:

If your test results show deficiency or if you have symptoms like persistent fatigue, weakness, or changes in cognitive function, consult a healthcare provider promptly.

Limitations

  • Does not reflect acute changes in folate status
  • May be inaccurate in patients with reticulocytosis
  • Requires careful sample protection from light

Risks & Considerations

  • Minor pain or bruising at the needle site
  • Lightheadedness or dizziness
  • Very rare risk of infection or excessive bleeding

Interfering Factors

  • Medications such as anticonvulsants or sulfasalazine
  • Recent folate supplementation
  • Hemolytic conditions that alter RBC lifespan
  • Improper sample handling or exposure to light

Compare With Similar Tests

TestFolate (Folic Acid) RBC TestSerum Folate TestVitamin B12 TestComplete Blood Count (CBC)
ComparisonFolate (Folic Acid) RBC Test

Frequently Asked Questions

What is the Folate RBC Test?
It is a blood test that measures the level of folate in red blood cells, providing a long-term assessment of folate status in the body.
Why is the Folate RBC Test important?
It helps diagnose folate deficiency, which can lead to anemia, fatigue, and serious complications like neural tube defects in pregnancy.
What are the common symptoms of folate deficiency?
Symptoms include weakness, fatigue, shortness of breath, irritability, pale skin, and mouth sores.
How is the Folate RBC Test performed?
A blood sample is drawn from a vein in your arm and analyzed in a laboratory using chemiluminescent immunoassay.
What is the normal range for RBC folate?
The normal range is typically 150-600 ng/mL, but this can vary slightly between laboratories.
What does a low folate level indicate?
A low level indicates folate deficiency, which may require dietary changes, supplementation, or further medical investigation.
Is fasting required for the Folate RBC Test?
No, fasting is not required for this test. However, follow any specific instructions from your healthcare provider.
How much does the Folate RBC Test cost in India?
The cost at DNA Labs India is INR 3500, including home sample collection.
How long does it take to get the test results?
Results are usually available on the same day if the sample is processed promptly.
Are there any risks associated with the test?
The risks are minimal, including slight bruising or discomfort at the blood draw site.
Can folate deficiency be treated?
Yes, it can be treated with dietary adjustments, folic acid supplements, or addressing underlying conditions.
Where can I get the Folate RBC Test done?
DNA Labs India offers this test with home collection in numerous cities across India. Book online or contact us for more information.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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