GJB3 Gene Deafness, autosomal dominant type 2B NGS Genetic Test
Short Name: GJB3 Deafness Type 2B NGS Test
Also known as: DFNA2B, GJB3-related hearing loss
GJB3 Gene Deafness, autosomal dominant type 2B NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Results are typically available within 3 to 4 weeks after sample collection.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
To detect pathogenic mutations in the GJB3 gene that cause autosomal dominant deafness type 2B, aiding in diagnosis, management, and genetic counseling for affected individuals and families.
- Test Code
- 2306
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- Results are typically available within 3 to 4 weeks after sample collection.
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No specific preparation is required. Genetic counseling is recommended to discuss test implications and draw a family pedigree chart.
Method: Blood draw or saliva collection
Laboratory Analysis
A small blood sample or saliva will be collected by a trained phlebotomist; the process is simple and painless.
Report Delivery
Apply pressure to the puncture site for a few minutes if blood was drawn. No specific restrictions after collection.
Timeline: Results are typically available within 3 to 4 weeks after sample collection.
Patient Instructions
About This Test
Who Should Get This Test
To detect pathogenic mutations in the GJB3 gene that cause autosomal dominant deafness type 2B, aiding in diagnosis, management, and genetic counseling for affected individuals and families.
How to Prepare
- No fasting required
- Bring a valid ID and prescription if available
- Inform the technician about any blood-thinning medications or health conditions
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Genetic testing for GJB3 mutations is essential for identifying the cause of autosomal dominant hearing loss, enabling early intervention, management, and family counseling."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Insufficient sample volume
- Hemolyzed or clotted samples
- Improperly labeled or contaminated samples
Understanding Your Results
Diagnosis of GJB3-related autosomal dominant deafness is supported. Genetic counseling and management plans should be initiated, including hearing assessments and family testing.
Further testing, family studies, or functional assays may be needed. Consult a geneticist for clarification and monitoring.
GJB3-related deafness is unlikely, and other genetic or non-genetic causes of hearing loss should be explored through additional evaluations.
If you have a family history of hearing loss, experience progressive hearing loss, or have unexplained hearing impairment, consult a geneticist or ENT specialist for evaluation and testing recommendations.
Limitations
- ⚠May not detect all genetic variants
- ⚠Not a diagnostic for all causes of hearing loss
- ⚠Results require genetic counseling for interpretation
Risks & Considerations
- ●Minimal risk from blood draw (e.g., bruising, infection)
- ●Psychological impact of test results, such as anxiety
- ●Possible detection of incidental findings not related to deafness
Interfering Factors
- ●Sample contamination
- ●Degraded DNA
- ●Hemolyzed blood samples
Compare With Similar Tests
| Test | GJB3 Gene Deafness, autosomal dominant type 2B NGS Genetic Test | GJB2 Gene Deafness Test | SLC26A4 Gene Test | TMC1 Gene Test | Comprehensive Hearing Loss Panel |
|---|---|---|---|---|---|
| Comparison | GJB3 Gene Deafness, autosomal dominant type 2B NGS Genetic Test |
Frequently Asked Questions
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₹20,000Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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