GLB1 Gene GM1-gangliosidosis type 1 NGS Genetic Test
Short Name: GM1-gangliosidosis Type 1 NGS Test
Also known as: GLB1 Gene Sequencing Test, GM1-gangliosidosis Genetic Diagnosis, Lysosomal Storage Disorder Genetic Test
GLB1 Gene GM1-gangliosidosis type 1 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Reports are typically available within 3 to 4 weeks after sample collection.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of the GLB1 Gene GM1-gangliosidosis type 1 NGS Genetic Test is to identify mutations in the GLB1 gene for accurate diagnosis of GM1-gangliosidosis type 1, enabling early intervention, genetic counseling, and informed family planning decisions.
- Test Code
- 2061
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- Reports are typically available within 3 to 4 weeks after sample collection.
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
Genetic counseling is recommended before testing to discuss implications and obtain informed consent.
Method: Venipuncture
Laboratory Analysis
A blood sample is collected via venipuncture under aseptic conditions.
Report Delivery
The sample is labeled and transported to the laboratory for NGS analysis.
Timeline: Reports are typically available within 3 to 4 weeks after sample collection.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the GLB1 Gene GM1-gangliosidosis type 1 NGS Genetic Test is to identify mutations in the GLB1 gene for accurate diagnosis of GM1-gangliosidosis type 1, enabling early intervention, genetic counseling, and informed family planning decisions.
How to Prepare
- Ensure proper patient identification
- Use sterile equipment for venipuncture
- Collect blood in an EDTA tube
- Transport sample at room temperature within 24 hours
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Genetic testing for GM1-gangliosidosis type 1 is crucial for early diagnosis, allowing for better symptom management and genetic counseling for families. It helps in understanding inheritance patterns and planning for supportive care."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood sample
- Insufficient sample volume
- Improper labeling or contamination
Understanding Your Results
If symptoms of GM1-gangliosidosis type 1 are present, for genetic counseling before or after testing, or to discuss family planning and risk assessment.
Limitations
- ⚠May not detect all types of genetic mutations, such as large deletions or intronic variants
- ⚠Results should be interpreted in conjunction with clinical findings and family history
- ⚠Does not predict disease severity or progression
Risks & Considerations
- ●Minimal risk from blood draw, such as bruising or infection at the site
- ●Psychological impact of receiving genetic results
- ●Potential for variants of uncertain significance that may cause anxiety
Interfering Factors
- ●Sample contamination
- ●Degraded or insufficient DNA quality
Compare With Similar Tests
| Test | GLB1 Gene GM1-gangliosidosis type 1 NGS Genetic Test | Sanger Sequencing | Enzyme Activity Assay |
|---|---|---|---|
| Comparison | GLB1 Gene GM1-gangliosidosis type 1 NGS Genetic Test |
Frequently Asked Questions
What is GM1-gangliosidosis type 1?
How is GM1-gangliosidosis type 1 inherited?
What are the common symptoms of GM1-gangliosidosis type 1?
How is GM1-gangliosidosis type 1 diagnosed?
What does the GLB1 Gene NGS Genetic Test involve?
What is the cost of the GM1-gangliosidosis type 1 NGS Genetic Test in India?
How long does it take to get results from this test?
Is home sample collection available for this test?
What should I do before taking the test?
How accurate is the NGS test for GM1-gangliosidosis type 1?
Can this test be used for carrier testing?
What happens if the test result is positive?
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Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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